Remote ischaemic pre-conditioning reduces intestinal ischaemia reperfusion injury in a newborn rat
Remote ischaemic pre-conditioning reduces intestinal ischaemia reperfusion injury in a newborn rat
Highlights
Iscahaemia-reperfusion injury is a key part of the pathogenesis of various intestinal pathologies including necrotising enterocolitis.
Remote ischaemic conditioning has shown significant promise in other contexts.
These data show that remote ischaemic pre-conditioning reduces both the extent of intestinal injury in a newborn rat model.
These data show that remote ischaemic pre-conditioning reduces the severity of intestinal injury in a newborn rat model.
This technology could very easily be translated to clinical practice.
1389-1398
Jones, Ian Howard
b9a778f7-29ce-4d8a-ab2b-f7a466b3d670
Tao, Denise
1da0c257-e36f-4aab-b2c6-fc47e48502e4
Vagdama, Bhumita
f583efe7-6765-4948-90ac-707ab75596d6
Orford, Michael
63865dab-e7dc-477a-bb39-ff9931eb659d
Eaton, Simon
f359f82a-496d-47ec-9c5b-8e982a3035af
Collins, Jane
0fd67c99-fa4f-4085-9e53-4af9174d924d
Hall, Nigel
6919e8af-3890-42c1-98a7-c110791957cf
1 July 2023
Jones, Ian Howard
b9a778f7-29ce-4d8a-ab2b-f7a466b3d670
Tao, Denise
1da0c257-e36f-4aab-b2c6-fc47e48502e4
Vagdama, Bhumita
f583efe7-6765-4948-90ac-707ab75596d6
Orford, Michael
63865dab-e7dc-477a-bb39-ff9931eb659d
Eaton, Simon
f359f82a-496d-47ec-9c5b-8e982a3035af
Collins, Jane
0fd67c99-fa4f-4085-9e53-4af9174d924d
Hall, Nigel
6919e8af-3890-42c1-98a7-c110791957cf
Jones, Ian Howard, Tao, Denise, Vagdama, Bhumita, Orford, Michael, Eaton, Simon, Collins, Jane and Hall, Nigel
(2023)
Remote ischaemic pre-conditioning reduces intestinal ischaemia reperfusion injury in a newborn rat.
Journal of Pediatric Surgery, 58 (7), .
Abstract
Highlights
Iscahaemia-reperfusion injury is a key part of the pathogenesis of various intestinal pathologies including necrotising enterocolitis.
Remote ischaemic conditioning has shown significant promise in other contexts.
These data show that remote ischaemic pre-conditioning reduces both the extent of intestinal injury in a newborn rat model.
These data show that remote ischaemic pre-conditioning reduces the severity of intestinal injury in a newborn rat model.
This technology could very easily be translated to clinical practice.
Text
RIC Manuscript - further revised submission
- Accepted Manuscript
More information
Accepted/In Press date: 26 November 2022
e-pub ahead of print date: 6 December 2022
Published date: 1 July 2023
Identifiers
Local EPrints ID: 472982
URI: http://eprints.soton.ac.uk/id/eprint/472982
ISSN: 0022-3468
PURE UUID: 0f78edee-84d9-4f30-b53d-c5f2cba200eb
Catalogue record
Date deposited: 06 Jan 2023 17:35
Last modified: 24 Apr 2025 01:43
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Contributors
Author:
Ian Howard Jones
Author:
Denise Tao
Author:
Bhumita Vagdama
Author:
Michael Orford
Author:
Simon Eaton
Author:
Jane Collins
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