READ ME File For 'Locus Coeruleus in Alzheimer's Disease MRI Study data ARUK'

Dataset DOI: 10.5258/SOTON/D2443

ReadMe Author: Rebecca Claire Beardmore, University of Southampton 0000-0002-3708-8929 

This dataset supports the thesis entitled Neuropathology of the Locus Coeruleus in Alzheimer's Disease
AWARDED BY: University of Southampton
DATE OF AWARD: 2022

DESCRIPTION OF THE DATA
Data collected from AD and control participants consented and recruited at the Memory Assessment & Research Centre, Southern Health NHSFT. This data contains: Demographic details, medical history, current medications, cognitive and functional assessment scores, blood pressure readings following various tasks designed to elicit autonomic nervous system responses. MR Images obtained at University Hospital Southampton NHSFT and analysed using ImageJ to give Locus coeruleus signal data.  Pupil light response measures obtained at Department of Psychology, UoS.  SPSS required to view the data. 

Date of data collection: January 2017 until October 2018


Licence:

Related projects/Funders:
Alzheimers Research UK, ARUK-PPG2016A-6

Related publication:
Hou, R., Beardmore, R., Holmes, C., Osmond, C and Darekar, A. A case-control study of the Locus Coeruleus degeneration in Alzheimer’s Disease. European Neuropsychopharmacology 2021, 43: 153-159. 


Date that the file was created: November, 2022