Patient study ID
age and gender matched participants
group, mild or moderate
Mean baseline size of pupil luminance level 1
Mean difference in pupil size for luminance level 1
Mean time to max constriction lumincance level 1
Mean baseline size of pupil luminance level 2
Mean difference in pupil size for luminance level 2
Mean time to max constriction lumincance level 2
Mean baseline size of pupil luminance level 3
Mean difference in pupil size for luminance level 3
Mean time to max constriction lumincance level 3
Mean baseline size of pupil luminance level 4
Mean difference in pupil size for luminance level 4
Mean time to max constriction lumincance level 4
age at screen
age at MRI
Gender
Years of full time education
Patient's main occupation
Marital status
Ethnic origin
Years since stopping smoking
Alcohol units per week
Year of onset of memory problems
Duration of memory problems in years
Year of diagnosis
Family history of dementia?
Infections over last 5 years
Left or Right handedness
are they taking acetylcholinesterase inhibitors?
Current medication 1
Current medication 2
Current medication 3
Current medication 4
Current medication 5
Current medication 6
Current medication 7
Current medication 8
Current medication 9
Current medication 10
Current medication 11
Current medication 12
Medical history 1
Medical history 2
Medical history 3
Medical history 4
Medical history 5
Medical history 6
Medical history 7
Medical history 8
Medical history 9
Medical history 10
Medical history 11
Medical history 12
Hachinski Scale
Height in cm
Weight in Kg
BMI
BP after 3 mins supine systolic
BP after 3 mins supine diastolic
Resting Heart Rate
Tympanic temperature
BP on standing systolic
BP on standing diastolic
Heart rate on standing
difference in BP systolic on standing
difference in BP dystolic on standing
difference in HR on standing
BP standing plus 3 mins systolic
BP standing plus 3 mins diastolic
Heart rate after standing for 3 mins
BP sitting for 3 mins systolic
BP sitting for 3 mins diastolic
Heart rate after resting for 3 mins seated
BP after serial subtraction systolic
BP after serial subtraction diastolic
Heart rate after serial subtraction
BP after 3 mins sitting rest systolic
BP after 3 mins sitting rest diastolic
Heart rate after resting 2
BP after cold pressor test systolic
BP after cold pressor test diastolic
Heart rate after cold pressor test
ECG overall interpretation
If abnormal, description of abnormality
R-R interval (msec)
PR interval (msec)
QRS (msec)
QT interval (msec)
QTc interval (msec)
MMSE Orientation
MMSE Immediate recall
MMSE Attention score WORLD
MMSE Delayed Recall
MMSE Language
MMSE total score
MOCA visuospatial score
MOCA naming score
MOCA Attention score
MOCA Language score
MOCA Abstraction score
MOCA Delayed Recall score
MOCA Orientation score
MoCA total score
Semantic Fluency - Number of words generated
ADAS word recall score average incorrect across 3 trials
ADAS Commands score number incorrect
ADAS constructionalpraxis score, number incorrect
ADAS naming score
ADAS Ideational Praxis score number of incorrect components
ADAS Orientation score number of incorrect answers
ADAS Word Recognition score number of errors, max score 12
ADAS Remembering test instructions
ADAS Comprehension instructions
ADAS Word Finding Difficulty
ADAS Spoken Language ability
ADAS Total score
ADAS Delayed Recall score No of incorrect responses
ADAS Concentration score
ADAS Maze task score
ADAS Number Cancellation score No of correct targets
time gone to bed
time to fall asleep (min)
time gotten up
no. of hours sleep
cannot get to sleep within 30minutes
wake up in night or early morning
get up to use bathroom at night
cannot breathe comfortably
cough or snore loudly
feel too cold
feel too hot
had bad dreams
have pain
any other reason please describe
other reason score
rate sleep quality overall
need medication to sleep
trouble staying awake during activity
enough enthusiasm to get things done
do you have a bed partner or room mate
Loud snoring
Pauses between breaths while asleep
Legs twitching or jerking while asleep
Disorientation or confusion during sleep
other restlessness while asleep please describe
Other restless score
PSQI Duration of sleep
PSQI Sleep Disturbance
PSQI Sleep latency
PSQI Day dysfunction
PSQI Sleep Efficiency
PSQI Overall Sleep Quality
PSQI need meds to sleep
PSQI Total score
group control or AD
ADCSADL total score
ADCSADL don't know responses
Delusions Frequency
Delusions Severity
Delusions Carer Distress
Hallucinations Frequency
Hallucinations Severity
Hallucinations Carer Distress
Agitation / Agression Frequency
Agitation / Agression Severity
Agitation Carer Distress
Depression Frequency
Depression Severity
Depression Carer Distress
Anxiety Frequency
Anxiety Severity
Anxiety Carer Distress
Elation /Euphoria Frequency
Elation/Euphoria Severity
Elation Carer Distress
Apathy /Indifference Frequency
Apathy /Indifference Severity
Apathy Carer Distress
Disinhibition Frequency
Disinhibition Severity
Disinhibition Carer Distress
Irritability / Lability Frequency
Irritability / Lability Severity
Irritability Carer Distress
Aberrant Motor behaviour Frequency
Aberrant Motor behaviour Severity
Motor behaviour Carer Distress
Sleep Frequency
Sleep Severity
Sleep Carer Distress
Appetite Frequency
Appetite Severity
Appetite Carer Distress
NPI total score
NPI carer distress score
Blinded ID
Level 3 Pons Signal intensity
Level 3 LLC Signal intensity
Level 3 LLC contrast ratio
Level 3 RLC Signal intensity
Level 3 RLC contrast ratio
Level 3 Average LLC & RLC Signal intensity
Level 3 Average LLC & RLC Contrast ratio
Level 3 LLC maximum signal intensity
Level 3 LLC contrast ratio using max SI
Level 3 RLC Maximum signal intensity
Level 3 RLC contrast ratio using max SI
Level 3 Average LLC & RLC max signal intensity
Level 3 Average LLC & RLC CR using max SI
Level 2 Pons Signal intensity
Level 2 LLC Signal intensity
Level 2 LLC contrast ratio
Level 2 RLC Signal intensity
Level 2 RLC contrast ratio
Level 2 Average LLC & RLC Signal intensity
Level 2 Average LLC & RLC Contrast ratio
Level 2 LLC maximum signal intensity
Level 2 LLC contrast ratio using max SI
Level 2 RLC Maximum signal intensity
Level 2 RLC contrast ratio using max SI
Level 2 Average LLC & RLC max signal intensity
Level 2 Average LLC & RLC CR using max SI
Level 1 Pons Signal intensity
Level 1 LLC Signal intensity
Level 1 LLC contrast ratio
Level 1 RLC Signal intensity
Level 1 RLC contrast ratio
Level 1 Average LLC & RLC Signal intensity
Level 1 Average LLC & RLC Contrast ratio
Level 1 LLC maximum signal intensity
Level 1 LLC contrast ratio using max SI
Level 1 RLC Maximum signal intensity
Level 1 RLC contrast ratio using max SI
Level 1 Average LLC & RLC max signal intensity
Level 1 Average LLC & RLC CR using max SI
Level 4 Pons Signal intensity
Level 4 LLC Signal intensity
Level 4 LLC contrast ratio
Level 4 RLC Signal intensity
Level 4 RLC contrast ratio
Level 4 Average LLC & RLC Signal intensity
Level 4 Average LLC & RLC Contrast ratio
Brightest slice average Pons SI
Brightest slice average LLC SI
Brightest slice LLC contrast ratio
Brightest slice RLC Signal intensity
Brightest slice RLC Contrast ratio
Brightest slice average LLC & RLC signal intensity
Brightest slice average LLC & RLC contrast ratio
Brightest slice max LLC SI
Brightest slice max LLC contrast ratio
Brightest slice max RLC Signal intensity
Brightest slice max RLC contrast ratio
Brightest slice average LLC & RLC max SI
Brightest slice average max LLC & RLC contrast ratio
Average LC-CR for total LC
sum of contrast ratios for all levels
APOE4 ug/l
IL10
IL6
TNF
Had MRI before
Did anyone explain risks and benefits of the procedure
Did staff explain what would be done during the scan
Did a member of staff answer your questions about the procedure
I felt anxious about the scan beforehand
I felt calm whilst in the scanner
I felt panicked in the scanner
I felt safe whilst in the scanner
I felt claustrophobic in the scanner
I felt like my head was getting hot
I found the scanner to be too noisy
I had to force myself to manage the situation
I had difficulty breathing during the scan
I found the length of the scan to be acceptable
Did you feel the machine could be harming you?
I would have this MRI scan again if I needed to
Any other comments