Patient centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children
Patient centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children
While non-operative treatment has emerged as an alternative to surgery for the treatment of uncomplicated acute appendicitis in children, comparative patient-centred outcomes are not well documented. We investigated these in a feasibility randomised trial. Of 57 randomised participants, data were available for 26. Compared with appendicectomy, children allocated to non-operative treatment reported higher short-term quality of life scores, shorter duration of requiring analgesia, more rapid return to normal activities and shorter parental absence from work. These preliminary data suggest differences exist in recovery profile and quality of life between these treatments that are important to measure in a larger RCT. Trial registration number is ISRCTN15830435.
Hall, Nigel
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Sherratt, Frances C.
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Eaton, Simon
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Walker, Erin
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Chorozoglou, Mary
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Beasant, Lucy
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Stanton, Michael P.
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Corbett, Harriet J
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Rex, Dean
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Hutchings, Natalie J
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Dixon, Elizabeth
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Crawley, Esther
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Blazeby, Jane
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Young, Bridget
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Reading, Isabel
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Hall, Nigel
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Sherratt, Frances C.
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Eaton, Simon
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Walker, Erin
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Chorozoglou, Mary
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Beasant, Lucy
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Stanton, Michael P.
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Corbett, Harriet J
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Rex, Dean
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Hutchings, Natalie J
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Dixon, Elizabeth
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Crawley, Esther
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Blazeby, Jane
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Young, Bridget
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Reading, Isabel
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Hall, Nigel, Sherratt, Frances C., Eaton, Simon, Walker, Erin, Chorozoglou, Mary, Beasant, Lucy, Stanton, Michael P., Corbett, Harriet J, Rex, Dean, Hutchings, Natalie J, Dixon, Elizabeth, Crawley, Esther, Blazeby, Jane, Young, Bridget and Reading, Isabel
(2023)
Patient centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children.
BMJ Paediatrics Open, 7 (1).
(In Press)
Abstract
While non-operative treatment has emerged as an alternative to surgery for the treatment of uncomplicated acute appendicitis in children, comparative patient-centred outcomes are not well documented. We investigated these in a feasibility randomised trial. Of 57 randomised participants, data were available for 26. Compared with appendicectomy, children allocated to non-operative treatment reported higher short-term quality of life scores, shorter duration of requiring analgesia, more rapid return to normal activities and shorter parental absence from work. These preliminary data suggest differences exist in recovery profile and quality of life between these treatments that are important to measure in a larger RCT. Trial registration number is ISRCTN15830435.
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Accepted/In Press date: 12 January 2023
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Local EPrints ID: 474348
URI: http://eprints.soton.ac.uk/id/eprint/474348
PURE UUID: 4129d6d7-9bcc-4901-b527-214bd446aa38
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Date deposited: 20 Feb 2023 18:06
Last modified: 17 Mar 2024 03:24
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Contributors
Author:
Frances C. Sherratt
Author:
Simon Eaton
Author:
Erin Walker
Author:
Lucy Beasant
Author:
Michael P. Stanton
Author:
Harriet J Corbett
Author:
Dean Rex
Author:
Natalie J Hutchings
Author:
Elizabeth Dixon
Author:
Esther Crawley
Author:
Jane Blazeby
Author:
Bridget Young
Author:
Isabel Reading
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