Mapping in the sequencing era
Mapping in the sequencing era
The present phase of the Human Genome Project is concerned with sequencing. The shift of emphasis has left an impression that mapping is in some sense complete or finished. On the contrary, faced with the challenges of mapping genes for complex traits and efforts to understand recombination and other biological processes, the need for accurate integrated metric maps is greater than ever. Furthermore, sequencing could be regarded as merely a way of improving the map, since the most useful 'end product' of the sequencing effort must be the annotated sequence that gives precise physical coordinates for markers and expressed sequences. Integration of both location and functional information, the latter provided by homology, expression and other functional studies, is the main target for the future.
Genome databases, Linkage mapping, Map integration, Single nucleotide polymorphism
76-84
Collins, Andrew
7daa83eb-0b21-43b2-af1a-e38fb36e2a64
1 September 1999
Collins, Andrew
7daa83eb-0b21-43b2-af1a-e38fb36e2a64
Abstract
The present phase of the Human Genome Project is concerned with sequencing. The shift of emphasis has left an impression that mapping is in some sense complete or finished. On the contrary, faced with the challenges of mapping genes for complex traits and efforts to understand recombination and other biological processes, the need for accurate integrated metric maps is greater than ever. Furthermore, sequencing could be regarded as merely a way of improving the map, since the most useful 'end product' of the sequencing effort must be the annotated sequence that gives precise physical coordinates for markers and expressed sequences. Integration of both location and functional information, the latter provided by homology, expression and other functional studies, is the main target for the future.
This record has no associated files available for download.
More information
Published date: 1 September 1999
Keywords:
Genome databases, Linkage mapping, Map integration, Single nucleotide polymorphism
Identifiers
Local EPrints ID: 474912
URI: http://eprints.soton.ac.uk/id/eprint/474912
ISSN: 0001-5652
PURE UUID: e623b7b3-2772-4f12-a319-d683a43b3fec
Catalogue record
Date deposited: 07 Mar 2023 17:30
Last modified: 17 Mar 2024 02:38
Export record
Altmetrics
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
