Myopia control effect of defocus incorporated multiple segments (DIMS) spectacle lens in Chinese children: results of a 3-year follow-up study
Myopia control effect of defocus incorporated multiple segments (DIMS) spectacle lens in Chinese children: results of a 3-year follow-up study
Aims: To determine myopia progression in children who continued to wear the defocus incorporated multiple segments (DIMS) lenses or switched from single vision (SV) to DIMS lenses for a 1-year period following a 2-year myopia control trial.
Methods: 128 children participated in this study. The children who had worn DIMS lenses continued to wear DIMS lenses (DIMS group), and children who had worn SV lenses switched to wear DIMS lenses (Control-to-DIMS group). Cycloplegic spherical equivalent refraction (SER) and axial length (AL) were measured at 6-month interval. Historical controls were age matched to the DIMS group at 24 months and used for comparing the third-year changes.
Results: Over 3 years, SER and AL changes in the DIMS group (n=65) were-0.52±0.69D and 0.31±0.26 mm; these changes were not statistically significant over time (repeated measures analysis of variance, p>0.05). SER (-0.04±0. 38D) and AL (0.08±0.12 mm) changes in the Control-to-DIMS group (n=55) in the third year were less compared with the first (mean difference=0.45 ± 0.30D, 0.21±0.11 mm, p<0.001) and second (0.34±0.30D, 0.12±0.10 mm, p<0.001) years. Changes in SER and AL in both groups over that period were significantly less than in the historical control group (DIMS vs historical control: mean difference=-0.18±0.42D, p=0.012; 0.08±0.15 mm, p=0.001; Control-to-DIMS versus historical control: adjusted mean differences=-0.30±0.42D, p<0.001; 0.12±0.16 mm, p<0.001). Conclusions: Myopia control effect was sustained in the third year in children who had used the DIMS spectacles in the previous 2 years and was also shown in the children switching from SV to DIMS lenses.
Child, Child, Preschool, China/epidemiology, Disease Progression, Eyeglasses, Follow-Up Studies, Humans, Myopia/therapy, Refraction, Ocular
1110-1114
Lam, Carly S.Y.
a026fe18-9e48-4a25-99d9-80c0fa1dc5c8
Tang, Wing Chun
f85ea433-5e85-48b2-b3ac-2966a1862761
Lee, Paul H.
02620eab-ae7f-4a1c-bad1-8a50e7e48951
Zhang, Han Yu
760188f7-5c68-46ae-aa37-9038586dd3d7
Qi, Hua
3404a8db-7d28-4147-9b8a-121f2446c72d
Hasegawa, Keigo
1c027638-57b9-47da-85fa-0f4c997e1bd8
To, Chi Ho
e004ab8c-47be-4179-878a-b457a4c2039c
1 August 2022
Lam, Carly S.Y.
a026fe18-9e48-4a25-99d9-80c0fa1dc5c8
Tang, Wing Chun
f85ea433-5e85-48b2-b3ac-2966a1862761
Lee, Paul H.
02620eab-ae7f-4a1c-bad1-8a50e7e48951
Zhang, Han Yu
760188f7-5c68-46ae-aa37-9038586dd3d7
Qi, Hua
3404a8db-7d28-4147-9b8a-121f2446c72d
Hasegawa, Keigo
1c027638-57b9-47da-85fa-0f4c997e1bd8
To, Chi Ho
e004ab8c-47be-4179-878a-b457a4c2039c
Lam, Carly S.Y., Tang, Wing Chun, Lee, Paul H., Zhang, Han Yu, Qi, Hua, Hasegawa, Keigo and To, Chi Ho
(2022)
Myopia control effect of defocus incorporated multiple segments (DIMS) spectacle lens in Chinese children: results of a 3-year follow-up study.
British Journal of Ophthalmology, 106 (8), .
(doi:10.1136/bjophthalmol-2020-317664).
Abstract
Aims: To determine myopia progression in children who continued to wear the defocus incorporated multiple segments (DIMS) lenses or switched from single vision (SV) to DIMS lenses for a 1-year period following a 2-year myopia control trial.
Methods: 128 children participated in this study. The children who had worn DIMS lenses continued to wear DIMS lenses (DIMS group), and children who had worn SV lenses switched to wear DIMS lenses (Control-to-DIMS group). Cycloplegic spherical equivalent refraction (SER) and axial length (AL) were measured at 6-month interval. Historical controls were age matched to the DIMS group at 24 months and used for comparing the third-year changes.
Results: Over 3 years, SER and AL changes in the DIMS group (n=65) were-0.52±0.69D and 0.31±0.26 mm; these changes were not statistically significant over time (repeated measures analysis of variance, p>0.05). SER (-0.04±0. 38D) and AL (0.08±0.12 mm) changes in the Control-to-DIMS group (n=55) in the third year were less compared with the first (mean difference=0.45 ± 0.30D, 0.21±0.11 mm, p<0.001) and second (0.34±0.30D, 0.12±0.10 mm, p<0.001) years. Changes in SER and AL in both groups over that period were significantly less than in the historical control group (DIMS vs historical control: mean difference=-0.18±0.42D, p=0.012; 0.08±0.15 mm, p=0.001; Control-to-DIMS versus historical control: adjusted mean differences=-0.30±0.42D, p<0.001; 0.12±0.16 mm, p<0.001). Conclusions: Myopia control effect was sustained in the third year in children who had used the DIMS spectacles in the previous 2 years and was also shown in the children switching from SV to DIMS lenses.
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Accepted/In Press date: 20 February 2021
Published date: 1 August 2022
Additional Information:
Funding Information:
Funding This was a collaborative research project supported by HOYA, Tokyo, Japan (PolyU grant numbers ZG5N), other PolyU grants: ZVN1, ZVN2, ZE1A, 8-8475, and by an RGC Research Impact Fund: R5032-18. The sponsor also provided specially manufactured spectacle lenses and frames.
Funding Information:
Competing interests This collaborative research was supported by HOYA Corporation, Tokyo, Japan. Patents titled ’Spectacle Lens’ in China (CN104678572 B) and USA (US10268050 B2) were issued on 27 April 2018 and 23 April 2019 respectively.
Publisher Copyright:
© 2022 BMJ Publishing Group. All rights reserved.
Keywords:
Child, Child, Preschool, China/epidemiology, Disease Progression, Eyeglasses, Follow-Up Studies, Humans, Myopia/therapy, Refraction, Ocular
Identifiers
Local EPrints ID: 474929
URI: http://eprints.soton.ac.uk/id/eprint/474929
ISSN: 0007-1161
PURE UUID: 91ec1f73-dad4-427c-a9a1-b350a02582b6
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Date deposited: 07 Mar 2023 17:35
Last modified: 18 Mar 2024 04:08
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Contributors
Author:
Carly S.Y. Lam
Author:
Wing Chun Tang
Author:
Paul H. Lee
Author:
Han Yu Zhang
Author:
Hua Qi
Author:
Keigo Hasegawa
Author:
Chi Ho To
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