Recent Progress in Decarboxylative Oxidative Cross-Coupling for Biaryl Synthesis
Recent Progress in Decarboxylative Oxidative Cross-Coupling for Biaryl Synthesis
The beginning of the 21st century has seen tremendous growth in the field of decarboxylative activation. Benzoic acid derivatives are now recognised as atom-economic alternatives to traditional cross-coupling partners, and they also benefit from being inexpensive, readily available and shelf-stable reagents. In this microreview we discuss recent developments in the coupling of benzoic acid derivatives either with an arene or with a second benzoic acid derivative, a process often termed decarboxylative oxidative cross-coupling. These procedures offer great promise for the development of highly selective and atom-economic cross-couplings.
Biaryls, Cross-coupling, C–H activation, Decarboxylation, Oxidative Coupling
3517-3527
Perry, Gregory J.P.
766e7fc8-abf3-4d1e-9949-c1b3439a2185
Larrosa, Igor
6ab25161-9d87-4f15-8559-0c0e59810989
7 July 2017
Perry, Gregory J.P.
766e7fc8-abf3-4d1e-9949-c1b3439a2185
Larrosa, Igor
6ab25161-9d87-4f15-8559-0c0e59810989
Perry, Gregory J.P. and Larrosa, Igor
(2017)
Recent Progress in Decarboxylative Oxidative Cross-Coupling for Biaryl Synthesis.
European Journal of Organic Chemistry, 2017 (25), .
(doi:10.1002/ejoc.201700121).
Abstract
The beginning of the 21st century has seen tremendous growth in the field of decarboxylative activation. Benzoic acid derivatives are now recognised as atom-economic alternatives to traditional cross-coupling partners, and they also benefit from being inexpensive, readily available and shelf-stable reagents. In this microreview we discuss recent developments in the coupling of benzoic acid derivatives either with an arene or with a second benzoic acid derivative, a process often termed decarboxylative oxidative cross-coupling. These procedures offer great promise for the development of highly selective and atom-economic cross-couplings.
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Published date: 7 July 2017
Additional Information:
Funding Information:
We gratefully acknowledge the Engineering and Physical Sciences Research Council (EPSRC) (EP/L014017/2) for funding.
Publisher Copyright:
© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Keywords:
Biaryls, Cross-coupling, C–H activation, Decarboxylation, Oxidative Coupling
Identifiers
Local EPrints ID: 475279
URI: http://eprints.soton.ac.uk/id/eprint/475279
ISSN: 1434-193X
PURE UUID: 6a6d78d5-af31-4430-8943-cf416c2e7211
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Date deposited: 14 Mar 2023 18:01
Last modified: 18 Mar 2024 04:11
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Contributors
Author:
Gregory J.P. Perry
Author:
Igor Larrosa
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