Towards the prediction of antimicrobial efficacy for hydrogen bonded, self-associating Amphiphiles
Towards the prediction of antimicrobial efficacy for hydrogen bonded, self-associating Amphiphiles
The antimicrobial efficacy of 50 supramolecular self-associating salts (SSAs) and related compounds was established against MRSA and E. coli. In addition, 14 different physicochemical properties were determined experimentally for each compound within this library. From these data we identified relationships between compound structure, physiochemical property, and antimicrobial activity.
2193-2205
Allen, Nyasha
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White, Lisa J.
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Boles, Jessica E.
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Williams, George
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Chu, Dominique F.
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Ellaby, Rebecca J.
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Shepherd, Helena J.
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Ng, Kendrick K. L.
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Blackholly, Laura R.
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Wilson, Ben
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Mulvihill, Daniel P.
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Hiscock, Jennifer
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15 September 2020
Allen, Nyasha
340bcea8-ba6f-4500-b739-4d41b25bdcca
White, Lisa J.
66137725-b91a-4157-ba97-56607f2dbadf
Boles, Jessica E.
13ce5778-19eb-4276-8328-d865a86f3c2c
Williams, George
26810522-92ef-4b61-a766-582bf15be280
Chu, Dominique F.
07506191-c069-4788-a873-b3f4345752a8
Ellaby, Rebecca J.
0b21ccab-3a2d-441f-bb52-d71c3f936ba9
Shepherd, Helena J.
70664bbb-30b9-4f37-bc31-a8a0e2dc8894
Ng, Kendrick K. L.
7feaf1ab-f3e1-4b68-a5ac-a797adfa805f
Blackholly, Laura R.
c8063cc4-ec80-40e7-bdd6-af1dd40c43c1
Wilson, Ben
3698e23f-6697-46c8-a902-b1c2f4dcb797
Mulvihill, Daniel P.
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Hiscock, Jennifer
c748d645-c150-4751-97bd-54e376f87d01
Allen, Nyasha, White, Lisa J., Boles, Jessica E., Williams, George and Hiscock, Jennifer
,
et al.
(2020)
Towards the prediction of antimicrobial efficacy for hydrogen bonded, self-associating Amphiphiles.
ChemMedChem, 15 (22), .
(doi:10.1002/cmdc.202000533).
Abstract
The antimicrobial efficacy of 50 supramolecular self-associating salts (SSAs) and related compounds was established against MRSA and E. coli. In addition, 14 different physicochemical properties were determined experimentally for each compound within this library. From these data we identified relationships between compound structure, physiochemical property, and antimicrobial activity.
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Accepted/In Press date: 15 September 2020
Published date: 15 September 2020
Identifiers
Local EPrints ID: 475630
URI: http://eprints.soton.ac.uk/id/eprint/475630
ISSN: 1860-7179
PURE UUID: 06e9a6ea-098c-4df8-b5ab-2251ffc1e40f
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Date deposited: 22 Mar 2023 17:48
Last modified: 17 Mar 2024 04:17
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Contributors
Author:
Nyasha Allen
Author:
Lisa J. White
Author:
Jessica E. Boles
Author:
George Williams
Author:
Dominique F. Chu
Author:
Rebecca J. Ellaby
Author:
Helena J. Shepherd
Author:
Kendrick K. L. Ng
Author:
Laura R. Blackholly
Author:
Ben Wilson
Author:
Daniel P. Mulvihill
Author:
Jennifer Hiscock
Corporate Author: et al.
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