The University of Southampton
University of Southampton Institutional Repository

Identifying research priorities in breast cancer surgery: a UK priority setting partnership with the James Lind Alliance

Identifying research priorities in breast cancer surgery: a UK priority setting partnership with the James Lind Alliance
Identifying research priorities in breast cancer surgery: a UK priority setting partnership with the James Lind Alliance
Purpose: A James Lind Alliance priority setting partnership was developed to identify research priorities in breast cancer surgery from individuals with lived experience, at high genetic risk of breast cancer, and healthcare professionals (HCPs).
Methods: 'Uncertainties' were collected using an online survey. Following an evidence check and development of summary questions, an interim survey asked participants to rank their top 10 research priorities from the question list. Top-ranked questions from patient/carer, high-risk and professional groups were carried forward for discussion to a final online prioritisation workshop.
Results: 260 participants (101 patients/carers, 156 HCPs) submitted 940 uncertainties via the initial survey. These were analysed thematically into 128 summary questions in six topic areas. Following evidence checking, 59 questions were included in the interim survey which was completed by 572 respondents. Marked differences were seen in questions prioritised by patients/carers, HCPs and women at high-risk. The top eight priorities in patient/carer and professional groups and top two priorities for high-risk women were carried forward to the online workshop at which 22 participants discussed and agreed the final top 10. Key themes included de-escalation of breast and axillary surgery, factors impacting the development/detection of locoregional recurrence and optimal provision of support for informed treatment decision-making.
Conclusion: The top 10 research priorities in breast cancer surgery have been agreed. However, the observed differences in research priorities identified by patients and professional groups were not anticipated. Top priorities from both groups should inform future UK breast cancer surgical research, to ensure that it addresses questions that are important to breast cancer community as a whole.
Breast cancer surgery, Consensus, James Lind Alliance, Research priorities
0167-6806
39-49
Potter, Shelley
846066f0-1336-45e1-828b-dfdedfc5c1be
Fairhurst, Katherine
2e7ac11b-017b-4ee4-a777-90b9b1887cc4
Cowan, Katherine
fcc235c9-3a39-484b-9e5e-f310bf724071
Vincent, Simon
66efd12b-ecd3-4cc9-a153-5ebff9e2fdb6
Lewis, Ian
9a4bc401-38a4-4a92-a2b5-020a82f13d98
Cutress, Ramsey I
68ae4f86-e8cf-411f-a335-cdba51797406
Stobart, Hilary
70e14214-0454-464d-bb11-6a38206b99bf
Fairbrother, Patricia
137b0bd8-d286-42f0-b41a-71a084976cb0
Turner, Sophia
2ad1d2e8-2818-4f85-9f9c-c30a4b56623c
Davies-Crowley, Kayleigh
d3c98ec7-c07b-4647-a268-e54e4bc6dc68
Jeevan, Ranjeet
faa2d6cc-ee25-4b2c-96d3-da79931d3bf3
Rattay, Tim
0ff56298-6769-44bf-8a22-a1620486e256
O'Connell, Rachel
d177e9cb-660b-43b1-9dc5-8d20ff96543f
Bundred, Nigel
81763280-2028-45e7-82ac-d04f3c04c5dc
McIntosh, Stuart A
64e6b959-5e9c-4755-a352-4554f625ec2b
et al.
Potter, Shelley
846066f0-1336-45e1-828b-dfdedfc5c1be
Fairhurst, Katherine
2e7ac11b-017b-4ee4-a777-90b9b1887cc4
Cowan, Katherine
fcc235c9-3a39-484b-9e5e-f310bf724071
Vincent, Simon
66efd12b-ecd3-4cc9-a153-5ebff9e2fdb6
Lewis, Ian
9a4bc401-38a4-4a92-a2b5-020a82f13d98
Cutress, Ramsey I
68ae4f86-e8cf-411f-a335-cdba51797406
Stobart, Hilary
70e14214-0454-464d-bb11-6a38206b99bf
Fairbrother, Patricia
137b0bd8-d286-42f0-b41a-71a084976cb0
Turner, Sophia
2ad1d2e8-2818-4f85-9f9c-c30a4b56623c
Davies-Crowley, Kayleigh
d3c98ec7-c07b-4647-a268-e54e4bc6dc68
Jeevan, Ranjeet
faa2d6cc-ee25-4b2c-96d3-da79931d3bf3
Rattay, Tim
0ff56298-6769-44bf-8a22-a1620486e256
O'Connell, Rachel
d177e9cb-660b-43b1-9dc5-8d20ff96543f
Bundred, Nigel
81763280-2028-45e7-82ac-d04f3c04c5dc
McIntosh, Stuart A
64e6b959-5e9c-4755-a352-4554f625ec2b

Potter, Shelley, Fairhurst, Katherine, Cowan, Katherine, Vincent, Simon and Cutress, Ramsey I , et al. (2023) Identifying research priorities in breast cancer surgery: a UK priority setting partnership with the James Lind Alliance. Breast Cancer Research and Treatment, 197 (1), 39-49. (doi:10.1007/s10549-022-06756-4).

Record type: Review

Abstract

Purpose: A James Lind Alliance priority setting partnership was developed to identify research priorities in breast cancer surgery from individuals with lived experience, at high genetic risk of breast cancer, and healthcare professionals (HCPs).
Methods: 'Uncertainties' were collected using an online survey. Following an evidence check and development of summary questions, an interim survey asked participants to rank their top 10 research priorities from the question list. Top-ranked questions from patient/carer, high-risk and professional groups were carried forward for discussion to a final online prioritisation workshop.
Results: 260 participants (101 patients/carers, 156 HCPs) submitted 940 uncertainties via the initial survey. These were analysed thematically into 128 summary questions in six topic areas. Following evidence checking, 59 questions were included in the interim survey which was completed by 572 respondents. Marked differences were seen in questions prioritised by patients/carers, HCPs and women at high-risk. The top eight priorities in patient/carer and professional groups and top two priorities for high-risk women were carried forward to the online workshop at which 22 participants discussed and agreed the final top 10. Key themes included de-escalation of breast and axillary surgery, factors impacting the development/detection of locoregional recurrence and optimal provision of support for informed treatment decision-making.
Conclusion: The top 10 research priorities in breast cancer surgery have been agreed. However, the observed differences in research priorities identified by patients and professional groups were not anticipated. Top priorities from both groups should inform future UK breast cancer surgical research, to ensure that it addresses questions that are important to breast cancer community as a whole.

This record has no associated files available for download.

More information

Accepted/In Press date: 29 September 2022
Published date: January 2023
Additional Information: Funding Information: This work was funded by the Association of Breast Surgery. Shelley Potter is an NIHR Clinician Scientist (CS-2016–16-019), Katherine Fairhurst and Tim Rattay are NIHR Clinical Lecturers. The views expressed in this publication are those of the authors and not necessarily those of the NHS, the National Institute for Health and Care Research or the Department of Health and Social Care. Publisher Copyright: © 2022, The Author(s).
Keywords: Breast cancer surgery, Consensus, James Lind Alliance, Research priorities

Identifiers

Local EPrints ID: 475637
URI: http://eprints.soton.ac.uk/id/eprint/475637
ISSN: 0167-6806
PURE UUID: b3956214-66b6-437f-8d82-f5779ca92818

Catalogue record

Date deposited: 23 Mar 2023 17:31
Last modified: 16 Mar 2024 23:44

Export record

Altmetrics

Contributors

Author: Shelley Potter
Author: Katherine Fairhurst
Author: Katherine Cowan
Author: Simon Vincent
Author: Ian Lewis
Author: Hilary Stobart
Author: Patricia Fairbrother
Author: Sophia Turner
Author: Kayleigh Davies-Crowley
Author: Ranjeet Jeevan
Author: Tim Rattay
Author: Rachel O'Connell
Author: Nigel Bundred
Author: Stuart A McIntosh
Corporate Author: et al.

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×