Surface modified NiTi smart biomaterials: surface engineering and biological compatibility
Surface modified NiTi smart biomaterials: surface engineering and biological compatibility
NiTi metallic biomaterials have a broad spectrum of clinical applications from heart stents to orthopedic implants. Recently, the use of NiTi smart biomaterials has received growing attention due to their striking features, including a low elastic modulus, shape memory behavior and acceptable biocompatibility. However, leaching of Ni ions from the surface of NiTi, the need for decreased elastic modulus and the desire for improved biological properties, including better material-cell interactions, biomineralization, and antibacterial activity, have provided the driving force for a wide variety of surface-modification techniques to address these problems before using NiTi in vivo. Depending on the target application, both dry and wet coating techniques have been employed to deposit biocompatible and bioactive layers over NiTi smart biomaterials. The influence of such coatings on the biological characteristics of the NiTi is illustrated. R&D activities have proved fruitful but much work needs to be done before clinical use of coated-NiTi.
Saman Safavi, Mir
5c05e9ea-aa5a-470b-b0ed-77735a16fefc
Bordbar-Khiabani, Aydin
046144f5-3cd8-4bfa-bd39-e1b24b08d9aa
Walsh, Frank
309528e7-062e-439b-af40-9309bc91efb2
Mozafari, Masoud
51fe30f2-7b57-45ca-9410-a420c37c074e
Khalil-Allafi, Jafar
cab125ae-bf75-4d42-b80d-93de81ecab0e
12 December 2022
Saman Safavi, Mir
5c05e9ea-aa5a-470b-b0ed-77735a16fefc
Bordbar-Khiabani, Aydin
046144f5-3cd8-4bfa-bd39-e1b24b08d9aa
Walsh, Frank
309528e7-062e-439b-af40-9309bc91efb2
Mozafari, Masoud
51fe30f2-7b57-45ca-9410-a420c37c074e
Khalil-Allafi, Jafar
cab125ae-bf75-4d42-b80d-93de81ecab0e
Saman Safavi, Mir, Bordbar-Khiabani, Aydin, Walsh, Frank, Mozafari, Masoud and Khalil-Allafi, Jafar
(2022)
Surface modified NiTi smart biomaterials: surface engineering and biological compatibility.
Current Opinion in Biomedical Engineering, 25, [100429].
(doi:10.1016/j.cobme.2022.100429).
Abstract
NiTi metallic biomaterials have a broad spectrum of clinical applications from heart stents to orthopedic implants. Recently, the use of NiTi smart biomaterials has received growing attention due to their striking features, including a low elastic modulus, shape memory behavior and acceptable biocompatibility. However, leaching of Ni ions from the surface of NiTi, the need for decreased elastic modulus and the desire for improved biological properties, including better material-cell interactions, biomineralization, and antibacterial activity, have provided the driving force for a wide variety of surface-modification techniques to address these problems before using NiTi in vivo. Depending on the target application, both dry and wet coating techniques have been employed to deposit biocompatible and bioactive layers over NiTi smart biomaterials. The influence of such coatings on the biological characteristics of the NiTi is illustrated. R&D activities have proved fruitful but much work needs to be done before clinical use of coated-NiTi.
Text
Accepted NiTi Review Script
- Accepted Manuscript
More information
Accepted/In Press date: 6 November 2022
e-pub ahead of print date: 17 November 2022
Published date: 12 December 2022
Identifiers
Local EPrints ID: 475935
URI: http://eprints.soton.ac.uk/id/eprint/475935
PURE UUID: 79059311-9637-49c7-bbd1-d36dc0b7cea9
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Date deposited: 31 Mar 2023 16:37
Last modified: 17 Mar 2024 07:41
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Contributors
Author:
Mir Saman Safavi
Author:
Aydin Bordbar-Khiabani
Author:
Masoud Mozafari
Author:
Jafar Khalil-Allafi
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