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Six action steps to address global disparities in Parkinson Disease: a World Health Organization priority

Six action steps to address global disparities in Parkinson Disease: a World Health Organization priority
Six action steps to address global disparities in Parkinson Disease: a World Health Organization priority
Special CommunicationL
Importance: The Global Burden of Disease study conducted between 1990 and 2016, based on a global study of 195 countries and territories, identified Parkinson disease (PD) as the fastest growing neurological disorder when measured using death and disability. Most people affected by PD live in low- and middle-income countries (LMICs) and experience large inequalities in access to neurological care and essential medicines. This Special Communication describes 6 actions steps that are urgently needed to address global disparities in PD.
Observations: The adoption by the 73rd World Health Assembly (WHA) of resolution 73.10 to develop an intersectoral global action plan on epilepsy and other neurological disorders in consultation with member states was the stimulus to coordinate efforts and leverage momentum to advance the agenda of neurological conditions, such as PD. In April 2021, the Brain Health Unit at the World Health Organization convened a multidisciplinary, sex-balanced, international consultation workshop, which identified 6 workable avenues for action within the domains of disease burden; advocacy and awareness; prevention and risk reduction; diagnosis, treatment, and care; caregiver support; and research.
Conclusions and Relevance: The dramatic increase of PD cases in many world regions and the potential costs of PD-associated treatment will need to be addressed to prevent possible health service strain. Across the board, governments, multilateral agencies, donors, public health organizations, and health care professionals constitute potential stakeholders who are urged to make this a priority.
2168-6149
929-936
Schiess, Nicoline
72d6b63a-b884-4197-a0e2-03ed8dde866a
Cataldi, Rodrigo
674fc310-1974-4d99-a24c-64a69814d586
Okun, Michael S.
3fc18b1c-f1e1-4f37-8ac0-d14c189c7764
Fothergill-Misbah, Natasha
22e115ca-ec36-4468-86f1-c781dcaf2c51
Schiess, Nicoline
72d6b63a-b884-4197-a0e2-03ed8dde866a
Cataldi, Rodrigo
674fc310-1974-4d99-a24c-64a69814d586
Okun, Michael S.
3fc18b1c-f1e1-4f37-8ac0-d14c189c7764
Fothergill-Misbah, Natasha
22e115ca-ec36-4468-86f1-c781dcaf2c51

Schiess, Nicoline, Cataldi, Rodrigo, Okun, Michael S. and Fothergill-Misbah, Natasha (2022) Six action steps to address global disparities in Parkinson Disease: a World Health Organization priority. JAMA Neurology, 79 (9), 929-936. (doi:10.1001/jamaneurol.2022.1783).

Record type: Review

Abstract

Special CommunicationL
Importance: The Global Burden of Disease study conducted between 1990 and 2016, based on a global study of 195 countries and territories, identified Parkinson disease (PD) as the fastest growing neurological disorder when measured using death and disability. Most people affected by PD live in low- and middle-income countries (LMICs) and experience large inequalities in access to neurological care and essential medicines. This Special Communication describes 6 actions steps that are urgently needed to address global disparities in PD.
Observations: The adoption by the 73rd World Health Assembly (WHA) of resolution 73.10 to develop an intersectoral global action plan on epilepsy and other neurological disorders in consultation with member states was the stimulus to coordinate efforts and leverage momentum to advance the agenda of neurological conditions, such as PD. In April 2021, the Brain Health Unit at the World Health Organization convened a multidisciplinary, sex-balanced, international consultation workshop, which identified 6 workable avenues for action within the domains of disease burden; advocacy and awareness; prevention and risk reduction; diagnosis, treatment, and care; caregiver support; and research.
Conclusions and Relevance: The dramatic increase of PD cases in many world regions and the potential costs of PD-associated treatment will need to be addressed to prevent possible health service strain. Across the board, governments, multilateral agencies, donors, public health organizations, and health care professionals constitute potential stakeholders who are urged to make this a priority.

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More information

Accepted/In Press date: 12 April 2022
e-pub ahead of print date: 11 July 2022
Additional Information: Funding Information: Additional Contributions: We gratefully acknowledge the contributions of the Edmond J. Safra Foundation for their financial support of the WHO consultation workshop, “Addressing the Public Health Importance of Parkinson Disease.” Funding Information: received grants from Edmond J. Safra Foundation paid to her institution during the conduct of the study. Dr Okun serves as a consultant for the Parkinson’s Foundation; has received research grants from the National Institutes of Health (NR014852, R01NS096008, U01NS119562, UH3 NS18-023, R21NS072897, R25NS108939), the Parkinson’s Foundation, the Michael J. Fox Foundation, the Smallwood Foundation, the Tourette Syndrome Association of America, and the UF Foundation; has received royalties for book publications with Demos, Manson, Amazon, Smashwords, Books4Patients, Perseus, Robert Rose, Oxford, and Cambridge; is an Associate Editor for New England Journal of Medicine Journal Watch Neurology; and has participated in CME and educational activities on movement disorders sponsored by the Academy for Healthcare Learning, PeerView, Prime, WebMD/Medscape, Medicus, MedNet, American Academy of Neurology, Movement Disorders Society, and Vanderbilt University. Dr Dorsey has received personal fees from the American Academy of Neurology, American Neurological Association, Excellus BlueCross BlueShield, International Parkinson’s and Movement Disorders Society, National Multiple Sclerosis Society, Northwestern University, Physicians Education Resource, PRIME Education, Stanford University, Texas Neurological Society, and Weill Cornell Honoraria; consulting fees from Abbott, AbbVie, Acadia, Acorda, Bial-Biotech Investments, Biogen, Boehringer Ingelheim, California Pacific Medical Center, Caraway Therapeutics, Curasen Therapeutics, Denali Therapeutics, Eli Lilly, Genentech/Roche, Grand Rounds, Huntington Study Group, Informa Pharma Consulting, Karger Publications, LifeSciences Consultants, MCM Education, Mediflix, Medopad, Medrhythms, Merck, Michael J. Fox Foundation, North American Center for Continuing Medical Education, Neurocrine, NeuroDerm, National Institutes of Health, Novartis, Origent Data Sciences, Otsuka, Physician’s Education Resource, Praxis, PRIME Education, Roche, Brown, McCarthy & Gruber, Sanofi, Seminal Healthcare, Spark, Springer Healthcare, Sunovion Pharma, Theravance, Voyager, and WebMD; grants from Biogen, Biosensics, Burroughs Wellcome Fund, CuraSen, Greater Rochester Health Foundation, Huntington Study Group, Michael J. Fox Foundation, National Institutes of Health, Patient-Centered Outcomes Research Institute, Pfizer, PhotoPharmics, Safra Foundation, and Wave Life Sciences; has performed editorial services for Karger Publications; owns stock in Included Health and Mediflix; and has ownership interests in SemCap outside the submitted work. Dr Bloem has received grants and personal fees from UCB and Zambon paid to his institution; personal fees from Critical Path Institute, AbbVie, Biogen, Roche, GE Healthcare, Novartis, and Bial paid to his institution during the conduct of the study; grants from the Netherlands Organisation for Scientific Research, Michael J. Fox Foundation, Stichting Woelse Waard, Alkemade Keuls, Maag Lever Darm Stichting, ParkinsonNL, Davis Phinney Foundation, Parkinson’s Foundation, Verily, Horizon 2020, Nothing Impossible, and Parkinson Vereniging outside the submitted work. Dr Bhidayasiri has received grants from Thailand Science Research and Innovation, Thailand Research Fund, and Chulalongkorn University; personal fees from Royal Society of Thailand, Abbott Pharmaceuticals, Lundbeck Pharmaceuticals, Teva Pharmaceuticals, Eisai Pharmaceuticals, and Otsuka Pharmaceuticals outside the submitted work; and has patents for laser-guided walking stick issued to Chulalongkorn University, for laser-guided walking stick issued, for nocturnal monitoring device issued, for tremor analysis device issued, and for a Parkinson cup pending. Dr Chishimba has received personal fees from Northwestern Medicine outside the submitted work. Dr Chowdhary has received grants from Edmond J. Safra Foundation during the conduct of the study. Dr Fung has received grants from AbbVie and nonfinancial support from Merz outside the submitted work. Dr Gifford has received personal fees from Michael J. Fox Foundation, Parkinson Canada, and University of Rochester outside the submitted work; and is president and cofounder of PD Avengers. Dr Kühn has received personal fees from Medtronic, Boston Scientific, Teva, and Abbott outside the submitted work. Dr Lim has reeived personal fees from Medtronic outside the submitted work. Dr Okubadejo has received grants from Michael J. Fox Foundation outside the submitted work. Dr Dua has received grants from Edmond J. Safra Foundation during the conduct of the study. No other disclosures were reported. Publisher Copyright: © 2022 American Medical Association. All rights reserved.

Identifiers

Local EPrints ID: 475976
URI: http://eprints.soton.ac.uk/id/eprint/475976
ISSN: 2168-6149
PURE UUID: 1e27c8b2-9709-4970-b257-11e6e4f36995
ORCID for Natasha Fothergill-Misbah: ORCID iD orcid.org/0000-0002-1192-6250

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Date deposited: 03 Apr 2023 16:46
Last modified: 17 Mar 2024 04:09

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Contributors

Author: Nicoline Schiess
Author: Rodrigo Cataldi
Author: Michael S. Okun

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