Bias in bones: Integrating sex into skeletal health and research policy to improve public health
Bias in bones: Integrating sex into skeletal health and research policy to improve public health
Personalised medicine has a growing role to play in improving diagnoses of conditions and providing tailored treatments. It is therefore uniquely placed to address growing skeletal health inequalities identified through this research. We have identified that preclinical laboratory experiments favour only one sex, resulting in clinical biases where drugs studied and optimised for women are also given to men. If not addressed this bias will also negatively impact the progress and effectiveness of sex specific therapies for skeletal disease. Development of sex-specific medicines and therapy for bone health should also be supported by robust research policy to avoid exacerbating these inequalities.
Clarkin, Claire
05cd2a88-1127-41aa-a29b-7ac323b4f3c9
11 November 2022
Clarkin, Claire
05cd2a88-1127-41aa-a29b-7ac323b4f3c9
Claire Clarkin (Author)
(2022)
Bias in bones: Integrating sex into skeletal health and research policy to improve public health
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Abstract
Personalised medicine has a growing role to play in improving diagnoses of conditions and providing tailored treatments. It is therefore uniquely placed to address growing skeletal health inequalities identified through this research. We have identified that preclinical laboratory experiments favour only one sex, resulting in clinical biases where drugs studied and optimised for women are also given to men. If not addressed this bias will also negatively impact the progress and effectiveness of sex specific therapies for skeletal disease. Development of sex-specific medicines and therapy for bone health should also be supported by robust research policy to avoid exacerbating these inequalities.
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Published date: 11 November 2022
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Local EPrints ID: 476014
URI: http://eprints.soton.ac.uk/id/eprint/476014
PURE UUID: 6220dc5d-ac17-4b98-9308-35d46c3ebe9f
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Date deposited: 04 Apr 2023 16:43
Last modified: 17 Mar 2024 01:37
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