DNA programmable assembly of nanoparticles into three-dimensional superlattices and their optical properties
DNA programmable assembly of nanoparticles into three-dimensional superlattices and their optical properties
In the last decades, the ability to program the assembly of nanoparticles into hierarchical mesoscale structures, has attracted profound interest in the scientific community for the fabrication of intricate 2D or 3D structures involving unique attributes. Deoxyribonucleic acid (DNA) has proven to be an exceptional tool for the assembly of complex nanoparticle structures, due to its inherit high specificity and selectivity as well as ease of chemical functionalisation, allowing for the design of a wide range of tailored mesoscale structures.
In this thesis, the DNA programmable assembly of nanoparticles of various sizes and composition was conducted by employing a number of different DNA design strategies (Chapter 3 and Chapter 4). To endow the resulting nanoparticle assemblies with additional stability against DNA denaturing conditions and further functionality (light-responsive), the 3-cyanovinyl carbazole nucleobase was incorporated within the DNA sequences. In addition, the successful, ordered assembly of upconversion nanoparticle crystals as well as heterogeneous gold/upconversion nanoparticle superlattices (Chapter 4) is reported for the first time.
A multimodal hyperspectral imaging setup and numerical simulations were employed to investigate and report for the first time the optical responses of three-dimensional DNA programmable gold nanoparticle superlattices (comprised of 15 nm spherical gold nanoparticles), down to single crystals (Chapter 5). Lastly, optical studies of heterogeneous gold/upconversion superlattices were carried out, providing insight on how the varying percentages of the constituent nanoparticles within the crystalline assemblies affect their optical properties.
University of Southampton
Misatziou, Doxi
455cd8ac-4bb1-485d-b6dd-c8609882017c
2023
Misatziou, Doxi
455cd8ac-4bb1-485d-b6dd-c8609882017c
Muskens, Otto
2284101a-f9ef-4d79-8951-a6cda5bfc7f9
Kanaras, Antonios
667ecfdc-7647-4bd8-be03-a47bf32504c7
Misatziou, Doxi
(2023)
DNA programmable assembly of nanoparticles into three-dimensional superlattices and their optical properties.
University of Southampton, Doctoral Thesis, 251pp.
Record type:
Thesis
(Doctoral)
Abstract
In the last decades, the ability to program the assembly of nanoparticles into hierarchical mesoscale structures, has attracted profound interest in the scientific community for the fabrication of intricate 2D or 3D structures involving unique attributes. Deoxyribonucleic acid (DNA) has proven to be an exceptional tool for the assembly of complex nanoparticle structures, due to its inherit high specificity and selectivity as well as ease of chemical functionalisation, allowing for the design of a wide range of tailored mesoscale structures.
In this thesis, the DNA programmable assembly of nanoparticles of various sizes and composition was conducted by employing a number of different DNA design strategies (Chapter 3 and Chapter 4). To endow the resulting nanoparticle assemblies with additional stability against DNA denaturing conditions and further functionality (light-responsive), the 3-cyanovinyl carbazole nucleobase was incorporated within the DNA sequences. In addition, the successful, ordered assembly of upconversion nanoparticle crystals as well as heterogeneous gold/upconversion nanoparticle superlattices (Chapter 4) is reported for the first time.
A multimodal hyperspectral imaging setup and numerical simulations were employed to investigate and report for the first time the optical responses of three-dimensional DNA programmable gold nanoparticle superlattices (comprised of 15 nm spherical gold nanoparticles), down to single crystals (Chapter 5). Lastly, optical studies of heterogeneous gold/upconversion superlattices were carried out, providing insight on how the varying percentages of the constituent nanoparticles within the crystalline assemblies affect their optical properties.
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DNA programmable assembly of nanoparticles into three-dimensional superlattices and their optical properties
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Published date: 2023
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Local EPrints ID: 476643
URI: http://eprints.soton.ac.uk/id/eprint/476643
PURE UUID: 4d2a1049-42a2-41b9-8838-6a8335fcd17b
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Date deposited: 10 May 2023 17:03
Last modified: 17 Mar 2024 03:18
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