Loss of muscle mass in the immediate post-operative period is associated with inadequate dietary protein and energy intake
Loss of muscle mass in the immediate post-operative period is associated with inadequate dietary protein and energy intake
Despite the implementation of 'Enhanced Recovery After Surgery' (ERAS) protocols, major abdominal surgery is still associated with significant and detrimental losses of muscle mass and function in the post-operative period. Although ERAS protocols advocate both early mobility and dietary intake, dietary composition in the immediate post-operative period is poorly characterised, despite muscle losses being greatest in this period. Herein, we show in 15 patients (66 ± 6 y, 12:3 M:F) who lost ~10% m. vastus lateralis muscle mass in the 5 days after open colorectal resective surgery, mean energy intake was only ~25% of the minimum ESPEN recommendation of 25 kcal/kg/d and daily dietary protein intake was only ~12% of the ESPEN recommended guidelines of 1.5 g/kg/d. Given the known importance of nutrition for muscle mass maintenance, innovative dietary interventions are needed in the immediate post-operative period, accounting for specific patient dietary preference to maximise compliance (e.g., soft-textured foods).
503-505
Hardy, E.J.
e333fdb7-52a2-420a-8f38-578b37e4107e
Deane, C.S.
3320532e-f411-4ea8-9a14-4a9f248da898
Lund, J.N.
839cc3ee-a082-44fe-add9-0efc6d96684f
Phillips, B.E.
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April 2023
Hardy, E.J.
e333fdb7-52a2-420a-8f38-578b37e4107e
Deane, C.S.
3320532e-f411-4ea8-9a14-4a9f248da898
Lund, J.N.
839cc3ee-a082-44fe-add9-0efc6d96684f
Phillips, B.E.
49f2a996-d264-483c-8d01-cf209eb5a23d
Hardy, E.J., Deane, C.S., Lund, J.N. and Phillips, B.E.
(2023)
Loss of muscle mass in the immediate post-operative period is associated with inadequate dietary protein and energy intake.
European Journal of Clinical Nutrition, 77 (4), .
(doi:10.1038/s41430-023-01264-0).
Abstract
Despite the implementation of 'Enhanced Recovery After Surgery' (ERAS) protocols, major abdominal surgery is still associated with significant and detrimental losses of muscle mass and function in the post-operative period. Although ERAS protocols advocate both early mobility and dietary intake, dietary composition in the immediate post-operative period is poorly characterised, despite muscle losses being greatest in this period. Herein, we show in 15 patients (66 ± 6 y, 12:3 M:F) who lost ~10% m. vastus lateralis muscle mass in the 5 days after open colorectal resective surgery, mean energy intake was only ~25% of the minimum ESPEN recommendation of 25 kcal/kg/d and daily dietary protein intake was only ~12% of the ESPEN recommended guidelines of 1.5 g/kg/d. Given the known importance of nutrition for muscle mass maintenance, innovative dietary interventions are needed in the immediate post-operative period, accounting for specific patient dietary preference to maximise compliance (e.g., soft-textured foods).
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s41430-023-01264-0
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Accepted/In Press date: 12 January 2023
e-pub ahead of print date: 26 January 2023
Published date: April 2023
Additional Information:
Funding Information:
We would like to thank Ms. Anna Quinn and Ms. Emma Bergin for their help with data collection. This research was funded by the Medical Research Council and Versus Arthritis via the MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (MR/P021220/1) and BBSRC (BB/R010358/1). CSD was supported by a Medical Research Council Skills Development Fellowship (MR/T026014/1).
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© 2023, The Author(s).
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Local EPrints ID: 477336
URI: http://eprints.soton.ac.uk/id/eprint/477336
ISSN: 0954-3007
PURE UUID: d81a790f-d510-4a5d-a2ee-9ebf90d88be4
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Date deposited: 05 Jun 2023 16:35
Last modified: 17 Mar 2024 04:15
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Author:
E.J. Hardy
Author:
C.S. Deane
Author:
J.N. Lund
Author:
B.E. Phillips
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