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Asia-pacific consensus on osteoporotic fracture prevention in postmenopausal women with low bone mass or osteoporosis but no fragility fractures

Asia-pacific consensus on osteoporotic fracture prevention in postmenopausal women with low bone mass or osteoporosis but no fragility fractures
Asia-pacific consensus on osteoporotic fracture prevention in postmenopausal women with low bone mass or osteoporosis but no fragility fractures
Postmenopausal women are at significant risk for osteoporotic fractures due to their rapid bone loss. Half of all postmenopausal women will get an osteoporosis-related fracture over their lifetime, with 25% developing a spine deformity and 15% developing a hip fracture. By 2050, more than half of all osteoporotic fractures will occur in Asia, with postmenopausal women being the most susceptible. Early management can halt or even reverse the progression of osteoporosis. Consequently, on October 31, 2020, the Taiwanese Osteoporosis Association hosted the Asia-Pacific (AP) Postmenopausal Osteoporotic Fracture Prevention (POFP) consensus meeting, which was supported by the Asian Federation of Osteoporosis Societies (AFOS) and the Asia Pacific Osteoporosis Foundation (APOF). International and domestic experts developed ten applicable statements for the prevention of osteoporotic fractures in postmenopausal women with low bone mass or osteoporosis but no fragility fractures in the AP region. The experts advocated, for example, that postmenopausal women with a high fracture risk be reimbursed for pharmaceutical therapy to prevent osteoporotic fractures. More clinical experience and data are required to modify intervention tactics.
Asia–pacific, Consensus, Osteoporosis, Osteoporotic fracture, Postmenopausal women, Prevention
0929-6646
S14-S20
Huang, Chun-Feng
7818b233-a111-4c77-a86e-7b1aca8d8d4a
Chen, Jung-Fu
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Reid, Ian R.
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Chan, Wing P.
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Ebeling, Peter Robert
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Langdahl, Bente
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Tu, Shih-Te
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Matsumoto, Toshio
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Chan, Ding-Cheng
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Chung, Yoon-Sok
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Chen, Fang-Ping
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Lewiecki, E Michael
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Tsai, Keh-Sung
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Yang, Rong-Sen
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Ang, Seng Bin
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Huang, Ko-En
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Chang, Yin-Fan
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Chen, Chung-Hwan
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Lee, Joon-Kiong
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Ma, Hsin-I
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Xia, Weibo
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Mithal, Ambrish
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Kendler, David L.
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Cooper, Cyrus
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Hwang, Jawl-Shan
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Wu, Chih-Hsing
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Huang, Chun-Feng
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Chen, Jung-Fu
52279e30-ef3e-48b7-9f88-1115c66cc88e
Reid, Ian R.
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Chan, Wing P.
21c0feb4-e8df-441e-8ac7-3a75e911bc40
Ebeling, Peter Robert
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Langdahl, Bente
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Tu, Shih-Te
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Matsumoto, Toshio
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Chan, Ding-Cheng
139d2b9f-9b27-4f62-be2b-a7eb64bc3ca4
Chung, Yoon-Sok
65d79d30-73f7-43c3-bba5-d1cc9a36e241
Chen, Fang-Ping
96078690-b31e-474b-ac95-16afc1a88dcf
Lewiecki, E Michael
6ada4ad7-3093-460f-9ad4-bfce9ab0ec4c
Tsai, Keh-Sung
5e67d438-a4d0-43fd-9169-9e32336db28a
Yang, Rong-Sen
a2e36d23-78f5-41c9-9371-e779ac964909
Ang, Seng Bin
db42a488-097c-4ead-9f06-ee37a47436b4
Huang, Ko-En
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Chang, Yin-Fan
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Chen, Chung-Hwan
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Lee, Joon-Kiong
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Ma, Hsin-I
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Xia, Weibo
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Mithal, Ambrish
d33d89ea-229f-465a-9049-f16b50e2f60d
Kendler, David L.
690099b2-d237-483f-8fd3-1e421f5950cc
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Hwang, Jawl-Shan
324cf57e-5755-499b-b70a-8a6035c863e2
Wu, Chih-Hsing
3ced97e6-01ac-4ef6-aee4-08d8290b0b53

Huang, Chun-Feng, Chen, Jung-Fu, Reid, Ian R., Chan, Wing P., Ebeling, Peter Robert, Langdahl, Bente, Tu, Shih-Te, Matsumoto, Toshio, Chan, Ding-Cheng, Chung, Yoon-Sok, Chen, Fang-Ping, Lewiecki, E Michael, Tsai, Keh-Sung, Yang, Rong-Sen, Ang, Seng Bin, Huang, Ko-En, Chang, Yin-Fan, Chen, Chung-Hwan, Lee, Joon-Kiong, Ma, Hsin-I, Xia, Weibo, Mithal, Ambrish, Kendler, David L., Cooper, Cyrus, Hwang, Jawl-Shan and Wu, Chih-Hsing (2023) Asia-pacific consensus on osteoporotic fracture prevention in postmenopausal women with low bone mass or osteoporosis but no fragility fractures. Journal of the Formosan Medical Association = Taiwan yi zhi, 122, S14-S20. (doi:10.1016/j.jfma.2023.01.013).

Record type: Article

Abstract

Postmenopausal women are at significant risk for osteoporotic fractures due to their rapid bone loss. Half of all postmenopausal women will get an osteoporosis-related fracture over their lifetime, with 25% developing a spine deformity and 15% developing a hip fracture. By 2050, more than half of all osteoporotic fractures will occur in Asia, with postmenopausal women being the most susceptible. Early management can halt or even reverse the progression of osteoporosis. Consequently, on October 31, 2020, the Taiwanese Osteoporosis Association hosted the Asia-Pacific (AP) Postmenopausal Osteoporotic Fracture Prevention (POFP) consensus meeting, which was supported by the Asian Federation of Osteoporosis Societies (AFOS) and the Asia Pacific Osteoporosis Foundation (APOF). International and domestic experts developed ten applicable statements for the prevention of osteoporotic fractures in postmenopausal women with low bone mass or osteoporosis but no fragility fractures in the AP region. The experts advocated, for example, that postmenopausal women with a high fracture risk be reimbursed for pharmaceutical therapy to prevent osteoporotic fractures. More clinical experience and data are required to modify intervention tactics.

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Accepted/In Press date: 29 January 2023
e-pub ahead of print date: 10 February 2023
Published date: 4 October 2023
Additional Information: Funding Information: We appreciate the participation of our TOA members. We are also grateful for the support of the AFOS and APOF for this meeting. This work was partially supported by a research grant from the Taiwanese Osteoporosis Association, Taiwan. This study was also partially funded by research grant MOST 108-2314-B-006-043-MY2 from the Ministry of Science and Technology.
Keywords: Asia–pacific, Consensus, Osteoporosis, Osteoporotic fracture, Postmenopausal women, Prevention

Identifiers

Local EPrints ID: 477447
URI: http://eprints.soton.ac.uk/id/eprint/477447
ISSN: 0929-6646
PURE UUID: 58b1b242-4b2a-4ab6-88cb-f738f7d66139
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709

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Date deposited: 06 Jun 2023 17:05
Last modified: 14 Aug 2024 01:35

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Contributors

Author: Chun-Feng Huang
Author: Jung-Fu Chen
Author: Ian R. Reid
Author: Wing P. Chan
Author: Peter Robert Ebeling
Author: Bente Langdahl
Author: Shih-Te Tu
Author: Toshio Matsumoto
Author: Ding-Cheng Chan
Author: Yoon-Sok Chung
Author: Fang-Ping Chen
Author: E Michael Lewiecki
Author: Keh-Sung Tsai
Author: Rong-Sen Yang
Author: Seng Bin Ang
Author: Ko-En Huang
Author: Yin-Fan Chang
Author: Chung-Hwan Chen
Author: Joon-Kiong Lee
Author: Hsin-I Ma
Author: Weibo Xia
Author: Ambrish Mithal
Author: David L. Kendler
Author: Cyrus Cooper ORCID iD
Author: Jawl-Shan Hwang
Author: Chih-Hsing Wu

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