Post-synthetic DNA modification with porphyrins for DNA templated supramolecular assemblies
Post-synthetic DNA modification with porphyrins for DNA templated supramolecular assemblies
The use of azide-alkyne cycloaddition (“click chemistry”), both Cu-catalysed and Cu-free, was probed to attach different porphyrins onto oligodeoxynucleotides (ODNs), and the efficiency was compared to amide coupling reaction. Terminal attachment using the different methodologies provides porphyrin-ODNs in varying yields, and the porphyrin-ODNs can be transformed into multiporphyrin arrays using DNA templated assembly. These arrays show exciton coupling between the porphyrin units and thus demonstrate an efficient and alternative route to multiporphyrin assemblies.
DNA bio-nanotechnology, click chemistry, exciton coupling, porphyrin, supramolecular arrays
1330-1339
Nikolaou, Vasilis
f4adad8e-767d-40d6-a411-c2425610e7f5
Wood, James William
db9db54a-ccb8-400f-a444-972fcf9d0c20
Charalambidis, Georgios
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Coutsolelos, Athanassios G.
ee1dc69e-5f00-4f79-9eb5-e5dd741fc99f
Stulz, Eugen
9a6c04cf-32ca-442b-9281-bbf3d23c622d
1 October 2023
Nikolaou, Vasilis
f4adad8e-767d-40d6-a411-c2425610e7f5
Wood, James William
db9db54a-ccb8-400f-a444-972fcf9d0c20
Charalambidis, Georgios
80d88fad-20fb-4b40-989d-d25f05e678f5
Coutsolelos, Athanassios G.
ee1dc69e-5f00-4f79-9eb5-e5dd741fc99f
Stulz, Eugen
9a6c04cf-32ca-442b-9281-bbf3d23c622d
Nikolaou, Vasilis, Wood, James William, Charalambidis, Georgios, Coutsolelos, Athanassios G. and Stulz, Eugen
(2023)
Post-synthetic DNA modification with porphyrins for DNA templated supramolecular assemblies.
Journal of Porphyrins and Phthalocyanines, 27 (7-10), .
(doi:10.1142/S108842462350092X).
Abstract
The use of azide-alkyne cycloaddition (“click chemistry”), both Cu-catalysed and Cu-free, was probed to attach different porphyrins onto oligodeoxynucleotides (ODNs), and the efficiency was compared to amide coupling reaction. Terminal attachment using the different methodologies provides porphyrin-ODNs in varying yields, and the porphyrin-ODNs can be transformed into multiporphyrin arrays using DNA templated assembly. These arrays show exciton coupling between the porphyrin units and thus demonstrate an efficient and alternative route to multiporphyrin assemblies.
Text
jpp230061 JPP manuscript Stulz accepted
- Accepted Manuscript
More information
Accepted/In Press date: 5 April 2023
Published date: 1 October 2023
Additional Information:
Publisher Copyright:
© 2023 World Scientific Publishing Company.
Keywords:
DNA bio-nanotechnology, click chemistry, exciton coupling, porphyrin, supramolecular arrays
Identifiers
Local EPrints ID: 477610
URI: http://eprints.soton.ac.uk/id/eprint/477610
ISSN: 1099-1409
PURE UUID: 9124e15a-0a3a-4781-9080-5011715004bb
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Date deposited: 09 Jun 2023 16:50
Last modified: 17 Mar 2024 03:07
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Contributors
Author:
Vasilis Nikolaou
Author:
James William Wood
Author:
Georgios Charalambidis
Author:
Athanassios G. Coutsolelos
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