Variations in penile cancer management: results: from the global society of rare genitourinary tumors survey
Variations in penile cancer management: results: from the global society of rare genitourinary tumors survey
Introduction: there is paucity of evidence and consensus on various aspects of management of penile cancer (PeCa), which is intuitive considering the rarity of this disease. We present here the details of an online survey conducted by the Global Society of Rare Genito-urinary Tumors (GSRGT) with the aim of capturing the variations in PeCa care across different regions of the world.
Materials and methods: an online questionnaire was developed by experts within the GSRGT and then circulated via email in English and Spanish versions to clinicians dealing with PeCa. Respondents were allowed 8 weeks to reply.
Results: we received 102 responses; the majority of them were from South America (37.2%) followed by North America and Asia (17.6% each). Only 11.7% of the respondents treated more than 25 patients with PeCa annually. Total penectomy is performed by 21.5% of the respondents in >50% of their patients. Less than a fifth of the experts (19.6%) responded that >50% of their patients are clinically node-negative (cN0) at presentation. For intermediate-risk cN0 patients (T1 G2 cancer), about a third of the experts chose surveillance. For invasive inguinal staging, the options of Dynamic Sentinel Lymph Node Biopsy (DSNB), Modified Inguinal Lymph Node Dissection (MILD), Superficial Inguinal Lymph Node Dissection (SILD), and Video-Endoscopic Inguinal Lymphadenectomy (VEIL) were chosen by 28.4%, 26.4%, 31.3%, and 13.7% of the respondents respectively. Considerable variation was seen in the worldwide use of these techniques. For clinically node-positive patients, respondents were in favor of giving adjuvant chemotherapy instead of neoadjuvant chemotherapy, except for cN3 patients.
Conclusion: the results of this questionnaire objectified the variations in global practices in the management of PeCa. This serves as the baseline information which can help prioritize research areas for multinational collaborative efforts, a key mission of the GSRGT.
GSRGT, carcinoma, divergence, genital, penis, questionnaire, rare tumors
376-382
Prakash, Gagan
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Arora, Amandeep
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Bandini, Marco
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Basile, Giuseppe
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Pal, Mahendra
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Griffiths, Gareth
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Cornes, Robert
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Zhu, Yao
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Rodriguez, Alejandro
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Alberson, Maarten
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Necchi, Andrea
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Master, Viraj
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Pettaway, Curtis A
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Spiess, Philippe E
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June 2023
Prakash, Gagan
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Arora, Amandeep
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Bandini, Marco
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Basile, Giuseppe
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Pal, Mahendra
80cc4f13-4bbf-4552-ae95-01e71f17a4f1
Griffiths, Gareth
7fd300c0-d279-4ff6-842d-aa1f2b9b864d
Cornes, Robert
6fc3ae22-41d2-4f7a-b141-a650e0ee436f
Zhu, Yao
4510fd53-b2eb-43db-8843-7398b152a880
Rodriguez, Alejandro
a6471a5b-f559-403b-8cd4-d470874cae63
Alberson, Maarten
b632c0a5-966c-4374-b61b-fc2c235ffb88
Necchi, Andrea
fb44790a-f8fe-43b6-ad82-72cf5b9107d6
Master, Viraj
5b674d5c-edfc-4eac-90c6-f35f62209283
Pettaway, Curtis A
3d85598c-555c-443a-b851-90407492a5ca
Spiess, Philippe E
8f29efde-65cc-4d98-8080-cb099b9fd36e
Prakash, Gagan, Arora, Amandeep, Bandini, Marco, Basile, Giuseppe, Pal, Mahendra, Griffiths, Gareth, Cornes, Robert, Zhu, Yao, Rodriguez, Alejandro, Alberson, Maarten, Necchi, Andrea, Master, Viraj, Pettaway, Curtis A and Spiess, Philippe E
(2023)
Variations in penile cancer management: results: from the global society of rare genitourinary tumors survey.
Clinical Genitourinary Cancer, 21 (3), .
(doi:10.1016/j.clgc.2023.03.001).
Abstract
Introduction: there is paucity of evidence and consensus on various aspects of management of penile cancer (PeCa), which is intuitive considering the rarity of this disease. We present here the details of an online survey conducted by the Global Society of Rare Genito-urinary Tumors (GSRGT) with the aim of capturing the variations in PeCa care across different regions of the world.
Materials and methods: an online questionnaire was developed by experts within the GSRGT and then circulated via email in English and Spanish versions to clinicians dealing with PeCa. Respondents were allowed 8 weeks to reply.
Results: we received 102 responses; the majority of them were from South America (37.2%) followed by North America and Asia (17.6% each). Only 11.7% of the respondents treated more than 25 patients with PeCa annually. Total penectomy is performed by 21.5% of the respondents in >50% of their patients. Less than a fifth of the experts (19.6%) responded that >50% of their patients are clinically node-negative (cN0) at presentation. For intermediate-risk cN0 patients (T1 G2 cancer), about a third of the experts chose surveillance. For invasive inguinal staging, the options of Dynamic Sentinel Lymph Node Biopsy (DSNB), Modified Inguinal Lymph Node Dissection (MILD), Superficial Inguinal Lymph Node Dissection (SILD), and Video-Endoscopic Inguinal Lymphadenectomy (VEIL) were chosen by 28.4%, 26.4%, 31.3%, and 13.7% of the respondents respectively. Considerable variation was seen in the worldwide use of these techniques. For clinically node-positive patients, respondents were in favor of giving adjuvant chemotherapy instead of neoadjuvant chemotherapy, except for cN3 patients.
Conclusion: the results of this questionnaire objectified the variations in global practices in the management of PeCa. This serves as the baseline information which can help prioritize research areas for multinational collaborative efforts, a key mission of the GSRGT.
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Accepted/In Press date: 1 March 2023
e-pub ahead of print date: 21 March 2023
Published date: June 2023
Keywords:
GSRGT, carcinoma, divergence, genital, penis, questionnaire, rare tumors
Identifiers
Local EPrints ID: 477757
URI: http://eprints.soton.ac.uk/id/eprint/477757
ISSN: 1558-7673
PURE UUID: af137e68-3f09-4799-b647-439568d7877e
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Date deposited: 14 Jun 2023 16:35
Last modified: 17 Mar 2024 03:36
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Contributors
Author:
Gagan Prakash
Author:
Amandeep Arora
Author:
Marco Bandini
Author:
Giuseppe Basile
Author:
Mahendra Pal
Author:
Robert Cornes
Author:
Yao Zhu
Author:
Alejandro Rodriguez
Author:
Maarten Alberson
Author:
Andrea Necchi
Author:
Viraj Master
Author:
Curtis A Pettaway
Author:
Philippe E Spiess
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