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Impact of fragility fractures on activities of daily living and productivity in community-dwelling women: a multi-national study

Impact of fragility fractures on activities of daily living and productivity in community-dwelling women: a multi-national study
Impact of fragility fractures on activities of daily living and productivity in community-dwelling women: a multi-national study

Purpose: to estimate the impact of fragility fractures on activities of daily living (ADL), productivity loss and caregiver support in women with a recent fragility fracture.

Methods: this multi-centre cross-sectional study enrolled community-dwelling women aged ≥50 years in South Korea, Spain, Germany, Australia and the United States. The fragility fracture cohort consisted of women with an index fragility fracture in the past 12 months; the fracture free cohort consisted of women with no fracture in the 18 months prior to study enrolment. Study participants completed three validated questionnaires: Lawton Instrumental ADL (IADL), Physical Self Maintenance Scale (PSMS) and iMTA Productivity Cost Questionnaire (iPCQ).

Results: in total, 1,253 participants from 41 sites across the five countries were included. Compared with the fracture free cohorts, fragility fracture cohorts had significantly lower function and were more dependent on support (p<0.05 in all countries for Lawton IADL, and in South Korea, Spain, Australia and the United States for PSMS), significantly higher hours of paid absenteeism (p<0.05, Spain, Germany, Australia), significantly higher unpaid lost productivity (p<0.05, South Korea, Spain, Germany), significantly more days of paid help received in the home (p<0.05 South Korea, Spain and the United States), and significantly more days of unpaid help from family members or friends (p<0.05, all countries).

Conclusion: in this multi-national study, fragility fractures in community-dwelling ≥50 years women were associated with several outcomes indicating higher indirect burden and lower quality of life, including more difficulties performing ADL and higher levels of lost productivity and caregiver support.
0937-941X
Yeh, Eric
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Rajkovic-Hooley, Olivera
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Silvey, Mark
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Ambler, Will S.
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Milligan, Gary
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Pinedo Villaneuva, Rafael
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Harvey, Nicholas
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Moayyeri, Alireza
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Yeh, Eric
fc3af98d-30d1-48db-bba0-71eb1c1e767e
Rajkovic-Hooley, Olivera
8f5e9b49-f650-4295-a45a-12ca6546834d
Silvey, Mark
a6cbd58e-e9a3-4048-addc-7e2bd7cbcacb
Ambler, Will S.
baa3f0bc-8bd7-4cf9-aafc-dc15790f3c95
Milligan, Gary
812e2377-8fc1-4609-803c-3e70756341b3
Pinedo Villaneuva, Rafael
44ed6e22-7f08-471d-874c-0e6ca4554283
Harvey, Nicholas
ce487fb4-d360-4aac-9d17-9466d6cba145
Moayyeri, Alireza
009152af-0b2d-4d41-ad96-edaabd862080

Yeh, Eric, Rajkovic-Hooley, Olivera, Silvey, Mark, Ambler, Will S., Milligan, Gary, Pinedo Villaneuva, Rafael, Harvey, Nicholas and Moayyeri, Alireza (2023) Impact of fragility fractures on activities of daily living and productivity in community-dwelling women: a multi-national study. Osteoporosis International. (In Press)

Record type: Article

Abstract


Purpose: to estimate the impact of fragility fractures on activities of daily living (ADL), productivity loss and caregiver support in women with a recent fragility fracture.

Methods: this multi-centre cross-sectional study enrolled community-dwelling women aged ≥50 years in South Korea, Spain, Germany, Australia and the United States. The fragility fracture cohort consisted of women with an index fragility fracture in the past 12 months; the fracture free cohort consisted of women with no fracture in the 18 months prior to study enrolment. Study participants completed three validated questionnaires: Lawton Instrumental ADL (IADL), Physical Self Maintenance Scale (PSMS) and iMTA Productivity Cost Questionnaire (iPCQ).

Results: in total, 1,253 participants from 41 sites across the five countries were included. Compared with the fracture free cohorts, fragility fracture cohorts had significantly lower function and were more dependent on support (p<0.05 in all countries for Lawton IADL, and in South Korea, Spain, Australia and the United States for PSMS), significantly higher hours of paid absenteeism (p<0.05, Spain, Germany, Australia), significantly higher unpaid lost productivity (p<0.05, South Korea, Spain, Germany), significantly more days of paid help received in the home (p<0.05 South Korea, Spain and the United States), and significantly more days of unpaid help from family members or friends (p<0.05, all countries).

Conclusion: in this multi-national study, fragility fractures in community-dwelling ≥50 years women were associated with several outcomes indicating higher indirect burden and lower quality of life, including more difficulties performing ADL and higher levels of lost productivity and caregiver support.

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Indirect Burden OP Fracture_Revised Manuscript Post Acceptance CLEAN (003) - Accepted Manuscript
Restricted to Repository staff only until 1 June 2024.
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Accepted/In Press date: 1 June 2023

Identifiers

Local EPrints ID: 477899
URI: http://eprints.soton.ac.uk/id/eprint/477899
ISSN: 0937-941X
PURE UUID: 0be38d16-5900-4bee-93ae-c0ca72d54897
ORCID for Nicholas Harvey: ORCID iD orcid.org/0000-0002-8194-2512

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Date deposited: 16 Jun 2023 16:32
Last modified: 17 Mar 2024 02:59

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Contributors

Author: Eric Yeh
Author: Olivera Rajkovic-Hooley
Author: Mark Silvey
Author: Will S. Ambler
Author: Gary Milligan
Author: Rafael Pinedo Villaneuva
Author: Nicholas Harvey ORCID iD
Author: Alireza Moayyeri

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