A dual-core NMR system for field-cycling singlet assisted diffusion NMR
A dual-core NMR system for field-cycling singlet assisted diffusion NMR
Long-lived singlet spin order offers the possibility to extend the spin memory by more than an order of magnitude. This enhancement can be used, among other applications, to assist NMR diffusion experiments in porous media where the extended lifetime of singlet spin order can be used to gain information about structural features of the medium as well as the dynamics of the imbibed phase. Other than offering the possibility to explore longer diffusion times of the order of many minutes that, for example, gives unprecedented access to tortuosity in structures with interconnected pores, singlet order has the important advantage to be immune to the internal field gradients generated by magnetic susceptibility inhomogeneities. These inhomogeneities, however, are responsible for very short T
2 decay constants in high magnetic field and this precludes access to the singlet order in the first instance. To overcome this difficulty and take advantage of singlet order in diffusion experiments in porous media, we have here developed a dual-core system with radiofrequency and 3-axis pulsed field gradients facilities in low magnetic field, for preparation and manipulation of singlet order and a probe, in high magnetic field, for polarisation and detection. The system operates in field-cycling and can be used for a variety of NMR experiments including diffusion tensor imaging (both singlet assisted and not). In this paper we present and discuss the new hardware and its calibration, and demonstrate its capabilities through a variety of examples.
NMR equipment, diffusion NMR, field cycling NMR, long-lived spin order, singlet assisted diffusion NMR
Robertson, Thomas B.R.
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Bannister, Rose C.
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Cartlidge, Topaz A.A.
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Hugger, Thimo
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Breham, Sebastien
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Zick, Klaus
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Engelke, Frank
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Thompson, Sam
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Pileio, Giuseppe
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2023
Robertson, Thomas B.R.
957b392c-1212-4721-bd6d-d1e00ed50a09
Bannister, Rose C.
2c343d30-5ad3-43df-9ed1-e7de21db958e
Cartlidge, Topaz A.A.
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Hugger, Thimo
189e3e06-4bec-43ed-84bc-9b087844a75f
Breham, Sebastien
3937350a-efda-4517-ace4-56b2fba32866
Zick, Klaus
dd96442c-60b4-4889-aaf9-2d8fb5023446
Engelke, Frank
0a2e7b0b-12c2-454f-949a-48564362974f
Thompson, Sam
99b7e34e-fe24-401c-b7b0-64e56cbbbcb1
Pileio, Giuseppe
13f78e66-0707-4438-b9c9-6dbd3eb7d4e8
Robertson, Thomas B.R., Bannister, Rose C., Cartlidge, Topaz A.A., Hugger, Thimo, Breham, Sebastien, Zick, Klaus, Engelke, Frank, Thompson, Sam and Pileio, Giuseppe
(2023)
A dual-core NMR system for field-cycling singlet assisted diffusion NMR.
Frontiers in Chemistry, 11, [1229586].
(doi:10.3389/fchem.2023.1229586).
Abstract
Long-lived singlet spin order offers the possibility to extend the spin memory by more than an order of magnitude. This enhancement can be used, among other applications, to assist NMR diffusion experiments in porous media where the extended lifetime of singlet spin order can be used to gain information about structural features of the medium as well as the dynamics of the imbibed phase. Other than offering the possibility to explore longer diffusion times of the order of many minutes that, for example, gives unprecedented access to tortuosity in structures with interconnected pores, singlet order has the important advantage to be immune to the internal field gradients generated by magnetic susceptibility inhomogeneities. These inhomogeneities, however, are responsible for very short T
2 decay constants in high magnetic field and this precludes access to the singlet order in the first instance. To overcome this difficulty and take advantage of singlet order in diffusion experiments in porous media, we have here developed a dual-core system with radiofrequency and 3-axis pulsed field gradients facilities in low magnetic field, for preparation and manipulation of singlet order and a probe, in high magnetic field, for polarisation and detection. The system operates in field-cycling and can be used for a variety of NMR experiments including diffusion tensor imaging (both singlet assisted and not). In this paper we present and discuss the new hardware and its calibration, and demonstrate its capabilities through a variety of examples.
Text
A_two_magnetic_core_NMR_system_with_RF_and_3D_gradient_capabilities_in_low_field
- Accepted Manuscript
Text
fchem-11-1229586
- Version of Record
More information
Accepted/In Press date: 22 June 2023
e-pub ahead of print date: 5 July 2023
Published date: 2023
Additional Information:
Funding Information:
The Leverhulme Trust supported this project through the Research Project Grant RPG-2019-298; The EPSRC United Kingdom supported this project through the grant EP/N033558/1.
Publisher Copyright:
Copyright © 2023 Robertson, Bannister, Cartlidge, Hugger, Breham, Zick, Engelke, Thompson and Pileio.
Keywords:
NMR equipment, diffusion NMR, field cycling NMR, long-lived spin order, singlet assisted diffusion NMR
Identifiers
Local EPrints ID: 478739
URI: http://eprints.soton.ac.uk/id/eprint/478739
ISSN: 2296-2646
PURE UUID: b618ffd9-df0c-4898-b28e-2a4c1a434947
Catalogue record
Date deposited: 07 Jul 2023 16:47
Last modified: 28 Aug 2024 02:01
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Contributors
Author:
Rose C. Bannister
Author:
Topaz A.A. Cartlidge
Author:
Thimo Hugger
Author:
Sebastien Breham
Author:
Klaus Zick
Author:
Frank Engelke
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