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Is leucocyte ascorbic acid an unreliable estimate of vitamin C deficiency?

Is leucocyte ascorbic acid an unreliable estimate of vitamin C deficiency?
Is leucocyte ascorbic acid an unreliable estimate of vitamin C deficiency?

Leucocyte ascorbic acid levels failed to identify six of seven elderly patients shown to be deficient on an oral vitamin C saturation test. Compared to those with a normal saturation test, patients judged deficient had lower levels for triceps skinfold thickness, mean arm muscle circumference and Quetelet's index; there was a significant association with the habit of eating alone, and with a dietary intake of less than 30 mg of ascorbic acid daily (the recommended daily allowance in the U.K.).

No significant difference was found in the values for haemoglobin, serum albumin or potassium concentrations between the two groups, and no association shown between a deficient saturation test and smoking, season, sublingual varicosities or an abnormal bleeding time.

0002-0729
243-247
Thomas, Anita J.
ae43a944-df9f-4fd9-a84c-0248ea6e05df
Briggs, Roger S.
a6b65ef0-e90c-4c07-bf5b-b70130c128b3
Monro, P.
f81a575a-e247-4d98-ba6c-a84c92c7553e
Thomas, Anita J.
ae43a944-df9f-4fd9-a84c-0248ea6e05df
Briggs, Roger S.
a6b65ef0-e90c-4c07-bf5b-b70130c128b3
Monro, P.
f81a575a-e247-4d98-ba6c-a84c92c7553e

Thomas, Anita J., Briggs, Roger S. and Monro, P. (1984) Is leucocyte ascorbic acid an unreliable estimate of vitamin C deficiency? Age and Ageing, 13 (4), 243-247. (doi:10.1093/ageing/13.4.243).

Record type: Article

Abstract

Leucocyte ascorbic acid levels failed to identify six of seven elderly patients shown to be deficient on an oral vitamin C saturation test. Compared to those with a normal saturation test, patients judged deficient had lower levels for triceps skinfold thickness, mean arm muscle circumference and Quetelet's index; there was a significant association with the habit of eating alone, and with a dietary intake of less than 30 mg of ascorbic acid daily (the recommended daily allowance in the U.K.).

No significant difference was found in the values for haemoglobin, serum albumin or potassium concentrations between the two groups, and no association shown between a deficient saturation test and smoking, season, sublingual varicosities or an abnormal bleeding time.

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Published date: July 1984

Identifiers

Local EPrints ID: 479056
URI: http://eprints.soton.ac.uk/id/eprint/479056
ISSN: 0002-0729
PURE UUID: 2de55a1e-6496-4890-abfd-30d50afafbd8

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Date deposited: 19 Jul 2023 16:39
Last modified: 17 Mar 2024 03:36

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Contributors

Author: Anita J. Thomas
Author: Roger S. Briggs
Author: P. Monro

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