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Eyetracking-enhanced VEP for nystagmus

Eyetracking-enhanced VEP for nystagmus
Eyetracking-enhanced VEP for nystagmus
Visual evoked potential (VEP) testing is an essential first stage in the diagnostic workup of patients with infantile nystagmus (IN). VEPs are an important factor in the diagnosis of albinism, which accompanies IN in ~28% of cases, as well as chiasmal, optic nerve and neurometabolic disease that can all present with IN. VEPs are also used to assess prognostic visual ability in cases of retinal dystrophy and optic nerve disease. Despite being used regularly in those with IN, VEP testing requires patients to keep the eyes still; something that people with IN naturally cannot do. Fixation instability during VEP testing is believed to reduce VEP signal amplitude, and as a result, the reliability of VEP may be reduced in one of the patient groups that needs it the most. This study investigates whether VEP signal quality (amplitude) can be improved in people with IN, by triggering acquisition only during the foveating (slow) periods of the nystagmus waveform.
Carter, Perry
b330105f-f4ee-4cbf-88bb-d2c97b9aa126
Shawkat, Fatima
10bffac1-9300-43f6-832e-11c0f1feca36
Self, Jay
0f6efc58-ae24-4667-b8d6-6fafa849e389
Lee, Helena
5d36fd1e-9334-4db5-b201-034d147133fb
Keeling, Eloise
3207bbdb-d391-44af-8abc-a60c08dce45b
Dunn, Matt
fab9d2ea-2428-4c2d-8c72-7c07515b7dfc
Carter, Perry
b330105f-f4ee-4cbf-88bb-d2c97b9aa126
Shawkat, Fatima
10bffac1-9300-43f6-832e-11c0f1feca36
Self, Jay
0f6efc58-ae24-4667-b8d6-6fafa849e389
Lee, Helena
5d36fd1e-9334-4db5-b201-034d147133fb
Keeling, Eloise
3207bbdb-d391-44af-8abc-a60c08dce45b
Dunn, Matt
fab9d2ea-2428-4c2d-8c72-7c07515b7dfc

Carter, Perry, Shawkat, Fatima, Self, Jay, Lee, Helena, Keeling, Eloise and Dunn, Matt (2023) Eyetracking-enhanced VEP for nystagmus. 2023 ARVO Annual Meeting, New Orleans Ernest N. Morial Convention Center, New Orleans, United States. 23 Apr - 27 Jul 2023. 1 pp .

Record type: Conference or Workshop Item (Poster)

Abstract

Visual evoked potential (VEP) testing is an essential first stage in the diagnostic workup of patients with infantile nystagmus (IN). VEPs are an important factor in the diagnosis of albinism, which accompanies IN in ~28% of cases, as well as chiasmal, optic nerve and neurometabolic disease that can all present with IN. VEPs are also used to assess prognostic visual ability in cases of retinal dystrophy and optic nerve disease. Despite being used regularly in those with IN, VEP testing requires patients to keep the eyes still; something that people with IN naturally cannot do. Fixation instability during VEP testing is believed to reduce VEP signal amplitude, and as a result, the reliability of VEP may be reduced in one of the patient groups that needs it the most. This study investigates whether VEP signal quality (amplitude) can be improved in people with IN, by triggering acquisition only during the foveating (slow) periods of the nystagmus waveform.

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More information

Published date: April 2023
Venue - Dates: 2023 ARVO Annual Meeting, New Orleans Ernest N. Morial Convention Center, New Orleans, United States, 2023-04-23 - 2023-07-27

Identifiers

Local EPrints ID: 479415
URI: http://eprints.soton.ac.uk/id/eprint/479415
PURE UUID: c5183f77-ce38-462d-940d-7dfeb42ef0ce
ORCID for Jay Self: ORCID iD orcid.org/0000-0002-1030-9963
ORCID for Helena Lee: ORCID iD orcid.org/0000-0002-2573-9536
ORCID for Eloise Keeling: ORCID iD orcid.org/0000-0003-0399-359X

Catalogue record

Date deposited: 21 Jul 2023 16:52
Last modified: 16 Apr 2024 01:56

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Contributors

Author: Perry Carter
Author: Fatima Shawkat
Author: Jay Self ORCID iD
Author: Helena Lee ORCID iD
Author: Eloise Keeling ORCID iD
Author: Matt Dunn

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