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Parathyroid hormone and 25-hydroxyvitamin D concentrations in sick and normal elderly people

Parathyroid hormone and 25-hydroxyvitamin D concentrations in sick and normal elderly people
Parathyroid hormone and 25-hydroxyvitamin D concentrations in sick and normal elderly people

Serum 25-hydroxyvitamin D and immunoreactive parathyroid hormone concentrations were measured in normal elderly subjects living at home and in sick elderly patients in hospital. Normal old people tended to have high 25-hydroxyvitamin D and low parathyroid hormone concentrations; in the sick elderly this pattern was reversed. The raised serum parathyroid hormone concentrations in the sick elderly were not due to poor renal function and may have been a response to vitamin D deficiency. A high serum parathyroid hormone concentration in an elderly patient must be interpreted in the light of the patient's general health and nutritional state. Caution is needed in diagnosing primary hyperparathyroidism in this age group.

25-Hydroxyvitamin D 2, Aged, Alkaline Phosphatase/blood, Ergocalciferols/analogs & derivatives, Female, Humans, Hyperparathyroidism/diagnosis, Kidney Diseases/blood, Male, Middle Aged, Parathyroid Hormone/blood
0267-0623
521-523
Petersen, M M
c5ef83b4-01d1-4b4d-a77e-3606892462fd
Briggs, R S
a6b65ef0-e90c-4c07-bf5b-b70130c128b3
Ashby, M A
40d14902-a6ca-4ddd-8bc3-6937f8bee93c
Reid, R I
c419aea6-9f32-4df3-bac1-b7c9d466d41f
Hall, M R
68b97e3b-4f5d-4fc5-8910-d7a8d4e8ce9a
Wood, P J
10f4c486-720f-4979-b9aa-9abf15193bc5
Clayton, B E
5b1918f2-fb4b-4ced-8c6c-40234479745f
Petersen, M M
c5ef83b4-01d1-4b4d-a77e-3606892462fd
Briggs, R S
a6b65ef0-e90c-4c07-bf5b-b70130c128b3
Ashby, M A
40d14902-a6ca-4ddd-8bc3-6937f8bee93c
Reid, R I
c419aea6-9f32-4df3-bac1-b7c9d466d41f
Hall, M R
68b97e3b-4f5d-4fc5-8910-d7a8d4e8ce9a
Wood, P J
10f4c486-720f-4979-b9aa-9abf15193bc5
Clayton, B E
5b1918f2-fb4b-4ced-8c6c-40234479745f

Petersen, M M, Briggs, R S, Ashby, M A, Reid, R I, Hall, M R, Wood, P J and Clayton, B E (1983) Parathyroid hormone and 25-hydroxyvitamin D concentrations in sick and normal elderly people. British Medical Journal (Clinical research ed.), 287, 521-523. (doi:10.1136/bmj.287.6391.521).

Record type: Article

Abstract

Serum 25-hydroxyvitamin D and immunoreactive parathyroid hormone concentrations were measured in normal elderly subjects living at home and in sick elderly patients in hospital. Normal old people tended to have high 25-hydroxyvitamin D and low parathyroid hormone concentrations; in the sick elderly this pattern was reversed. The raised serum parathyroid hormone concentrations in the sick elderly were not due to poor renal function and may have been a response to vitamin D deficiency. A high serum parathyroid hormone concentration in an elderly patient must be interpreted in the light of the patient's general health and nutritional state. Caution is needed in diagnosing primary hyperparathyroidism in this age group.

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More information

Published date: 20 August 1983
Keywords: 25-Hydroxyvitamin D 2, Aged, Alkaline Phosphatase/blood, Ergocalciferols/analogs & derivatives, Female, Humans, Hyperparathyroidism/diagnosis, Kidney Diseases/blood, Male, Middle Aged, Parathyroid Hormone/blood

Identifiers

Local EPrints ID: 479552
URI: http://eprints.soton.ac.uk/id/eprint/479552
ISSN: 0267-0623
PURE UUID: 45ff69a8-4825-473c-b275-7a189b338a40

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Date deposited: 26 Jul 2023 16:37
Last modified: 17 Mar 2024 03:42

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Contributors

Author: M M Petersen
Author: R S Briggs
Author: M A Ashby
Author: R I Reid
Author: M R Hall
Author: P J Wood
Author: B E Clayton

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