The allocation of funding into blast injury related research and traumatic brain injury between 2000-2019: An analysis of global investments from public and philanthropic funders
The allocation of funding into blast injury related research and traumatic brain injury between 2000-2019: An analysis of global investments from public and philanthropic funders
Background: There is little systematic tracking or detailed analysis of investments in research and development for blast injury to support decision-making around research funding.
Methods: This study examined global investments into blast injury-related research from public and philanthropic funders across 2000-2019. Research databases were searched using keywords, and open data was extracted from funder websites. Data collected included study title, abstract, award amount, funder, and year. Individual awards were categorised to compare amounts invested into different blast injuries, the scientific approaches taken and analysis of research investment into traumatic brain injury (TBI).
Findings: A total of 806 awards were identified into blast injury-related research globally, equating to $902.1 million (m, USD). There was a general increase in year-on-year investment between 2003 and 2009 followed by a consistent decline in annual funding since 2010. Pre-clinical research received $671.3m (74%) of investment. Brain-related injury research received $427.7m (47%), orthopaedic injury $138.6m (15%), eye injury $63.7m (7%) and ear injury $60.5m (7%). TBI research received a total investment of $384.3m, representing 42.6% of all blast injury-related research. The US Department of Defense funded $719.3m (80%).
Interpretation: Investment data suggests that TBI research has received greater funding than other blast injury health areas. The funding pattern observed can be seen as reactive, driven by the response to the War on Terror, the rising profile of TBI and congressionally mandated research.
Funding Statement: The authors gratefully acknowledge support from: RAEng Frontiers of Development Seed Funding, EPSRC Doctoral Prize, The Global Challenges Research Fund (GCRF) and The Royal Academy of Engineering (RAEng) (award no. RF/130).
Declaration of Interests: No benefits in any form have been or will be received from a commercial party related directly or indirectly to the subject of this manuscript.
Denny, J.W.
f1d0bbfd-965a-471e-a05c-9961c6c2916c
Brown, R.J.
52cf28bf-5ccc-408f-b4b3-0b77cefc0979
Head, M.G.
67ce0afc-2fc3-47f4-acf2-8794d27ce69c
Batchelor, J.
e53c36c7-aa7f-4fae-8113-30bfbb9b36ee
Dickinson, A.S.
626ef76a-f4d0-4287-a830-d92851574b3b
20 October 2020
Denny, J.W.
f1d0bbfd-965a-471e-a05c-9961c6c2916c
Brown, R.J.
52cf28bf-5ccc-408f-b4b3-0b77cefc0979
Head, M.G.
67ce0afc-2fc3-47f4-acf2-8794d27ce69c
Batchelor, J.
e53c36c7-aa7f-4fae-8113-30bfbb9b36ee
Dickinson, A.S.
626ef76a-f4d0-4287-a830-d92851574b3b
Denny, J.W., Brown, R.J., Head, M.G., Batchelor, J. and Dickinson, A.S.
(2020)
The allocation of funding into blast injury related research and traumatic brain injury between 2000-2019: An analysis of global investments from public and philanthropic funders.
(doi:10.2139/ssrn.3688866).
Abstract
Background: There is little systematic tracking or detailed analysis of investments in research and development for blast injury to support decision-making around research funding.
Methods: This study examined global investments into blast injury-related research from public and philanthropic funders across 2000-2019. Research databases were searched using keywords, and open data was extracted from funder websites. Data collected included study title, abstract, award amount, funder, and year. Individual awards were categorised to compare amounts invested into different blast injuries, the scientific approaches taken and analysis of research investment into traumatic brain injury (TBI).
Findings: A total of 806 awards were identified into blast injury-related research globally, equating to $902.1 million (m, USD). There was a general increase in year-on-year investment between 2003 and 2009 followed by a consistent decline in annual funding since 2010. Pre-clinical research received $671.3m (74%) of investment. Brain-related injury research received $427.7m (47%), orthopaedic injury $138.6m (15%), eye injury $63.7m (7%) and ear injury $60.5m (7%). TBI research received a total investment of $384.3m, representing 42.6% of all blast injury-related research. The US Department of Defense funded $719.3m (80%).
Interpretation: Investment data suggests that TBI research has received greater funding than other blast injury health areas. The funding pattern observed can be seen as reactive, driven by the response to the War on Terror, the rising profile of TBI and congressionally mandated research.
Funding Statement: The authors gratefully acknowledge support from: RAEng Frontiers of Development Seed Funding, EPSRC Doctoral Prize, The Global Challenges Research Fund (GCRF) and The Royal Academy of Engineering (RAEng) (award no. RF/130).
Declaration of Interests: No benefits in any form have been or will be received from a commercial party related directly or indirectly to the subject of this manuscript.
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Published date: 20 October 2020
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Local EPrints ID: 479553
URI: http://eprints.soton.ac.uk/id/eprint/479553
PURE UUID: eaac0c2b-7187-471a-a61a-13ee6ed92c2c
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Date deposited: 26 Jul 2023 16:37
Last modified: 17 Mar 2024 03:37
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J.W. Denny
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R.J. Brown
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A.S. Dickinson
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