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Timolol in migraine prophylaxis

Timolol in migraine prophylaxis
Timolol in migraine prophylaxis
The literature on the use of beta-blocking drugs in migraine suggests that not all such agents are effective. A double-blind crossover study of timolol in migraine prophylaxis was undertaken with fourteen patients, in order to assess the value of this drug in particular, and also to elucidate further the reason for the varied response to different beta-blockers. Timolol significantly reduced the frequency of migraine attacks, and was preferred to placebo. This supports the contention that beta-blocking drugs without intrinsic sympathomimetic activity are effective in migraine prophylaxis.
Female, Humans, Male, Migraine Disorders/prevention & control, Propanolamines/therapeutic use, Timolol/administration & dosage
0017-8748
379-381
Briggs, R S
a6b65ef0-e90c-4c07-bf5b-b70130c128b3
Millac, P A
5836dbe3-2d9f-4957-b280-4f7cd5ded5be
Briggs, R S
a6b65ef0-e90c-4c07-bf5b-b70130c128b3
Millac, P A
5836dbe3-2d9f-4957-b280-4f7cd5ded5be

Briggs, R S and Millac, P A (1979) Timolol in migraine prophylaxis. Headache, 19 (7), 379-381. (doi:10.1111/j.1526-4610.1979.hed1907379.x).

Record type: Article

Abstract

The literature on the use of beta-blocking drugs in migraine suggests that not all such agents are effective. A double-blind crossover study of timolol in migraine prophylaxis was undertaken with fourteen patients, in order to assess the value of this drug in particular, and also to elucidate further the reason for the varied response to different beta-blockers. Timolol significantly reduced the frequency of migraine attacks, and was preferred to placebo. This supports the contention that beta-blocking drugs without intrinsic sympathomimetic activity are effective in migraine prophylaxis.

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More information

Published date: November 1979
Keywords: Female, Humans, Male, Migraine Disorders/prevention & control, Propanolamines/therapeutic use, Timolol/administration & dosage

Identifiers

Local EPrints ID: 479626
URI: http://eprints.soton.ac.uk/id/eprint/479626
DOI: doi:10.1111/j.1526-4610.1979.hed1907379.x
ISSN: 0017-8748
PURE UUID: f7019313-cf74-451c-af7d-7a781c4acf85

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Date deposited: 26 Jul 2023 16:42
Last modified: 17 Mar 2024 03:43

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Contributors

Author: R S Briggs
Author: P A Millac

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