The effect of flavoxate on uninhibited detrusor contractions and urinary incontinence in the elderly
The effect of flavoxate on uninhibited detrusor contractions and urinary incontinence in the elderly
The effect of flavoxate, a smooth muscle relaxant, was investigated in 6 elderly patients with uninhibited detrusor contractions associated with urinary incontinence. Cystometry was done initially to confirm the diagnosis, immediately after an intravenous injection of 100 mg. flavoxate and after 200 mg. flavoxate orally 4 times daily for 7 days. No consistent drug effect could be detected cystometrically and incontinence was unchanged clinically.
Aged, Dose-Response Relationship, Drug, Flavonoids/therapeutic use, Flavoxate/administration & dosage, Humans, Muscle Contraction/drug effects, Urinary Incontinence/drug therapy
665-666
Briggs, R S
a6b65ef0-e90c-4c07-bf5b-b70130c128b3
Castleden, C M
ace1cafc-d68f-4b09-ad97-e8cd3056600d
Asher, M J
4953e00f-f520-458e-aa3c-8e8617f5c7b0
May 1980
Briggs, R S
a6b65ef0-e90c-4c07-bf5b-b70130c128b3
Castleden, C M
ace1cafc-d68f-4b09-ad97-e8cd3056600d
Asher, M J
4953e00f-f520-458e-aa3c-8e8617f5c7b0
Briggs, R S, Castleden, C M and Asher, M J
(1980)
The effect of flavoxate on uninhibited detrusor contractions and urinary incontinence in the elderly.
The Journal of Urology, 123 (5), .
(doi:10.1016/s0022-5347(17)56078-4).
Abstract
The effect of flavoxate, a smooth muscle relaxant, was investigated in 6 elderly patients with uninhibited detrusor contractions associated with urinary incontinence. Cystometry was done initially to confirm the diagnosis, immediately after an intravenous injection of 100 mg. flavoxate and after 200 mg. flavoxate orally 4 times daily for 7 days. No consistent drug effect could be detected cystometrically and incontinence was unchanged clinically.
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Published date: May 1980
Keywords:
Aged, Dose-Response Relationship, Drug, Flavonoids/therapeutic use, Flavoxate/administration & dosage, Humans, Muscle Contraction/drug effects, Urinary Incontinence/drug therapy
Identifiers
Local EPrints ID: 479642
URI: http://eprints.soton.ac.uk/id/eprint/479642
ISSN: 0022-5347
PURE UUID: 7348cf7d-1301-4bcc-80ca-f8464cdfcb60
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Date deposited: 26 Jul 2023 16:43
Last modified: 17 Mar 2024 03:43
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Author:
R S Briggs
Author:
C M Castleden
Author:
M J Asher
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