Milk osmolality: does it matter?
Milk osmolality: does it matter?
High osmolality of infant feed reflects a high concentration of solute particles and has been implicated as a cause of necrotising enterocolitis. Evidence for direct intestinal mucosal injury as a result of hyperosmolar feeds is scant, and no good evidence has been found to support such an association. High osmolality of enteral substrate may, however, slow down gastric emptying. Osmolality of current infant feeds ranges from around 300 mOsm/kg in human breast milk to just more than 400 mOsm/kg in fully fortified breast milk. Addition of mineral and vitamin supplements to small volumes of milk can increase osmolality significantly and should be avoided if possible.
F166-169
Pearson, Freya
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Johnson, Mark J.
ce07b5dd-b12b-47df-a5df-cd3b9447c9ed
Leaf, Alison A.
380f75d8-ccbd-4538-a45a-c4912fd86fc3
19 September 2011
Pearson, Freya
1d52a3d9-8d84-481a-8274-81cbdccbc40a
Johnson, Mark J.
ce07b5dd-b12b-47df-a5df-cd3b9447c9ed
Leaf, Alison A.
380f75d8-ccbd-4538-a45a-c4912fd86fc3
Pearson, Freya, Johnson, Mark J. and Leaf, Alison A.
(2011)
Milk osmolality: does it matter?
Archives of Disease in Childhood - Fetal and Neonatal Edition, 98 (2), .
(doi:10.1136/adc.2011.300492).
Abstract
High osmolality of infant feed reflects a high concentration of solute particles and has been implicated as a cause of necrotising enterocolitis. Evidence for direct intestinal mucosal injury as a result of hyperosmolar feeds is scant, and no good evidence has been found to support such an association. High osmolality of enteral substrate may, however, slow down gastric emptying. Osmolality of current infant feeds ranges from around 300 mOsm/kg in human breast milk to just more than 400 mOsm/kg in fully fortified breast milk. Addition of mineral and vitamin supplements to small volumes of milk can increase osmolality significantly and should be avoided if possible.
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Accepted/In Press date: 9 August 2011
Published date: 19 September 2011
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Local EPrints ID: 479794
URI: http://eprints.soton.ac.uk/id/eprint/479794
ISSN: 1359-2998
PURE UUID: 06a3592e-690a-4120-9701-9a37ac77bd8c
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Date deposited: 26 Jul 2023 17:04
Last modified: 17 Mar 2024 03:52
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Author:
Freya Pearson
Author:
Mark J. Johnson
Author:
Alison A. Leaf
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