Cohort profile: rationale and methods of UK Biobank repeat imaging study eye measures to study dementia

Accepted/In Press date: 22 May 2023

e-pub ahead of print date: 23 June 2023

Published date: 23 June 2023

Additional Information: Funding Information: The study sponsor/funder was not involved in the design of the study; the collection, analysis and interpretation of data; writing the report; and did not impose any restrictions regarding the publication of the report. UK Biobank is funded by the Medical Research Council, Wellcome Trust, Department of Health, Scottish Government, the Welsh Assembly Government, British Heart Foundation, Cancer Research UK, NIHR and the Northwest Regional Development Agency. The UK Biobank Eye and Vision Consortium is supported by grants from Moorfields Eye Charity, the NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, the Alcon Research Institute and the International Glaucoma Association (UK). AK, AP, ZS, PJF and PJP receive salary support from the NIHR BRC at Moorfields Eye Hospital & UCL Institute of Ophthalmology. NA receives salary support from University of Oxford and UK Biobank. PJF receives support from the Desmond Foundation, London, UK. AK is supported by a UKRI Future Leaders Fellowship and an Alcon Research Institute Young Investigator Award. TM acknowledges support from NHS Lothian R&D and the Clinical Research Facility at the University of Edinburgh. The authors acknowledge a proportion of our financial support from the UK Department of Health through an award made by the National Institute for Health Research to Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology for a Biomedical Research Centre for Ophthalmology. Funding Information: PJF reports personal fees from Allergan, Carl Zeiss, Google/DeepMind and Santen, a grant from Alcon, outside the submitted work. PJP reports grants from Topcon Inc, outside the scope of the current report. AK reports personal fees from Abbvie, Aerie, Google Health, Novartis, Reichert, Santen and Thea, outside the submitted work. AP reports grant support for remyelination trials in multiple sclerosis to the Amsterdam University Medicam Centre, Department of Neurology, MS Centre (RESTORE trial) and UCL, London RECOVER trial; Fight for Sight (nimodipine in optic neuritis trial); royalties or licenses from Up-to-Date (Wolters Kluver) on a book chapter; speaker fees for the Heidelberg Academy; participation on Advisory Board SC Zeiss OCTA Angi-Network, SC Novartis OCTiMS study; equipment: OCTA from Zeiss (Plex Elite). Funding Information: The study sponsor/funder was not involved in the design of the study; the collection, analysis and interpretation of data; writing the report; and did not impose any restrictions regarding the publication of the report. UK Biobank is funded by the Medical Research Council, Wellcome Trust, Department of Health, Scottish Government, the Welsh Assembly Government, British Heart Foundation, Cancer Research UK, NIHR and the Northwest Regional Development Agency. The UK Biobank Eye and Vision Consortium is supported by grants from Moorfields Eye Charity, the NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, the Alcon Research Institute and the International Glaucoma Association (UK). AK, AP, ZS, PJF and PJP receive salary support from the NIHR BRC at Moorfields Eye Hospital & UCL Institute of Ophthalmology. NA receives salary support from University of Oxford and UK Biobank. PJF receives support from the Desmond Foundation, London, UK. AK is supported by a UKRI Future Leaders Fellowship and an Alcon Research Institute Young Investigator Award. TM acknowledges support from NHS Lothian R&D and the Clinical Research Facility at the University of Edinburgh. The authors acknowledge a proportion of our financial support from the UK Department of Health through an award made by the National Institute for Health Research to Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology for a Biomedical Research Centre for Ophthalmology. Publisher Copyright: © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.

Keywords: dementia, epidemiology, ophthalmology

Local EPrints ID: 479805

URI: http://eprints.soton.ac.uk/id/eprint/479805

DOI: doi:10.1136/bmjopen-2022-069258

ISSN: 2044-6055

PURE UUID: e961c389-fe97-4fe2-97a8-951734de8122

ORCID for Andrew Lotery: orcid.org/0000-0001-5541-4305

Date deposited: 26 Jul 2023 17:12

Last modified: 06 Jun 2024 01:41