Eyetracking-enhanced VEP for nystagmus
Eyetracking-enhanced VEP for nystagmus
Visual evoked potential (VEP) testing is an essential first stage in the diagnostic workup of patients with infantile nystagmus (IN). VEPs are an important factor in the diagnosis of albinism, which accompanies IN in ~28% of cases, as well as chiasmal, optic nerve and neurometabolic disease that can all present with IN. VEPs are also used to assess prognostic visual ability in cases of retinal dystrophy and optic nerve disease. Despite being used regularly in those with IN, VEP testing requires patients to keep the eyes still; something that people with IN naturally cannot do. Fixation instability during VEP testing is believed to reduce VEP signal amplitude, and as a result, the reliability of VEP may be reduced in one of the patient groups that needs it the most. This study investigates whether VEP signal quality (amplitude) can be improved in people with IN, by triggering acquisition only during the foveating (slow) periods of the nystagmus waveform.
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Carter, Perry
b330105f-f4ee-4cbf-88bb-d2c97b9aa126
Shawkat, Fatima
10bffac1-9300-43f6-832e-11c0f1feca36
Self, Jay
0f6efc58-ae24-4667-b8d6-6fafa849e389
Lee, Helena
5d36fd1e-9334-4db5-b201-034d147133fb
Keeling, Eloise
3207bbdb-d391-44af-8abc-a60c08dce45b
Dunn, Matt
fab9d2ea-2428-4c2d-8c72-7c07515b7dfc
20 June 2023
Carter, Perry
b330105f-f4ee-4cbf-88bb-d2c97b9aa126
Shawkat, Fatima
10bffac1-9300-43f6-832e-11c0f1feca36
Self, Jay
0f6efc58-ae24-4667-b8d6-6fafa849e389
Lee, Helena
5d36fd1e-9334-4db5-b201-034d147133fb
Keeling, Eloise
3207bbdb-d391-44af-8abc-a60c08dce45b
Dunn, Matt
fab9d2ea-2428-4c2d-8c72-7c07515b7dfc
Carter, Perry, Shawkat, Fatima, Self, Jay, Lee, Helena, Keeling, Eloise and Dunn, Matt
(2023)
Eyetracking-enhanced VEP for nystagmus.
Investigative Ophthalmology & Visual Science, 64 (8), .
Abstract
Visual evoked potential (VEP) testing is an essential first stage in the diagnostic workup of patients with infantile nystagmus (IN). VEPs are an important factor in the diagnosis of albinism, which accompanies IN in ~28% of cases, as well as chiasmal, optic nerve and neurometabolic disease that can all present with IN. VEPs are also used to assess prognostic visual ability in cases of retinal dystrophy and optic nerve disease. Despite being used regularly in those with IN, VEP testing requires patients to keep the eyes still; something that people with IN naturally cannot do. Fixation instability during VEP testing is believed to reduce VEP signal amplitude, and as a result, the reliability of VEP may be reduced in one of the patient groups that needs it the most. This study investigates whether VEP signal quality (amplitude) can be improved in people with IN, by triggering acquisition only during the foveating (slow) periods of the nystagmus waveform.
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e-pub ahead of print date: 20 June 2023
Published date: 20 June 2023
Identifiers
Local EPrints ID: 479845
URI: http://eprints.soton.ac.uk/id/eprint/479845
ISSN: 0146-0404
PURE UUID: a830ccd6-9496-4d7d-bc53-2c9c89aeff98
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Date deposited: 27 Jul 2023 16:02
Last modified: 18 Mar 2024 03:02
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Contributors
Author:
Perry Carter
Author:
Fatima Shawkat
Author:
Eloise Keeling
Author:
Matt Dunn
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