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Vibrational spectroscopy for rapid bedside medical diagnosis

Vibrational spectroscopy for rapid bedside medical diagnosis
Vibrational spectroscopy for rapid bedside medical diagnosis
Vibrational spectroscopy, in the form of Raman and Mid-IR spectroscopies, is a powerful, label-free technique that can identify and quantify individual components of a complex chemical mixture which makes it ideal for analysis of biosamples. Vibrational spectroscopic measurements are quick, simple and easy to perform, making the screening rapid and can be employed for the diagnosis of multiple conditions at once. We explore the use of vibrational spectroscopy for rapid point of care diagnosis. As an example, we study the diagnosis of neonatal respiratory distress syndrome of preterm babies. We are developing on-chip spectroscopy using low-cost and highly sensitive disposable chips. Together with machine learning, it will further simplify biomarker detection in the critical care for rapid and early diagnosis of disease.
Veluthandath, Aneesh Vincent
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Ahmed, Waseem
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Osborne, Eleanor
e4b069c7-c295-45d2-a802-12a35f4fc9ad
Dushianthan, Ahilanandan
013692a2-cf26-4278-80bd-9d8fcdb17751
Madsen, Jens
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Clark, Howard W.
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Postle, Anthony
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Wilkinson, James S
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Murugan, Ganapathy Senthil
a867686e-0535-46cc-ad85-c2342086b25b
Veluthandath, Aneesh Vincent
6a183413-e10f-4374-bc64-a33bf7fd9cfa
Ahmed, Waseem
bd8069b9-786f-4dd1-b3f0-cf94d828a3b2
Osborne, Eleanor
e4b069c7-c295-45d2-a802-12a35f4fc9ad
Dushianthan, Ahilanandan
013692a2-cf26-4278-80bd-9d8fcdb17751
Madsen, Jens
3a6a1da5-83bd-4fdb-9786-bfd46aed8b1d
Clark, Howard W.
d237bb0a-ab8f-4b97-8ad2-bbfe73314260
Postle, Anthony
0fa17988-b4a0-4cdc-819a-9ae15c5dad66
Wilkinson, James S
73483cf3-d9f2-4688-9b09-1c84257884ca
Murugan, Ganapathy Senthil
a867686e-0535-46cc-ad85-c2342086b25b

Veluthandath, Aneesh Vincent, Ahmed, Waseem, Osborne, Eleanor, Dushianthan, Ahilanandan, Madsen, Jens, Clark, Howard W., Postle, Anthony, Wilkinson, James S and Murugan, Ganapathy Senthil (2023) Vibrational spectroscopy for rapid bedside medical diagnosis. Photonics 2023, Indian Institute of Science, Bangalore, India. 05 - 08 Jul 2023. 4 pp .

Record type: Conference or Workshop Item (Paper)

Abstract

Vibrational spectroscopy, in the form of Raman and Mid-IR spectroscopies, is a powerful, label-free technique that can identify and quantify individual components of a complex chemical mixture which makes it ideal for analysis of biosamples. Vibrational spectroscopic measurements are quick, simple and easy to perform, making the screening rapid and can be employed for the diagnosis of multiple conditions at once. We explore the use of vibrational spectroscopy for rapid point of care diagnosis. As an example, we study the diagnosis of neonatal respiratory distress syndrome of preterm babies. We are developing on-chip spectroscopy using low-cost and highly sensitive disposable chips. Together with machine learning, it will further simplify biomarker detection in the critical care for rapid and early diagnosis of disease.

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More information

Published date: 5 July 2023
Additional Information: Invited Talk
Venue - Dates: Photonics 2023, Indian Institute of Science, Bangalore, India, 2023-07-05 - 2023-07-08
Learn more about the Zepler Institute for Photonics and Nanoelectronics Learn more about the Zepler Institute for Photonics and Nanoelectronics

Identifiers

Local EPrints ID: 480595
URI: http://eprints.soton.ac.uk/id/eprint/480595
PURE UUID: 28af8796-eddf-4c6d-94f8-eb554b7db183
ORCID for Aneesh Vincent Veluthandath: ORCID iD orcid.org/0000-0003-4306-6723
ORCID for Waseem Ahmed: ORCID iD orcid.org/0000-0001-7172-264X
ORCID for Eleanor Osborne: ORCID iD orcid.org/0000-0003-0347-6891
ORCID for Ahilanandan Dushianthan: ORCID iD orcid.org/0000-0002-0165-3359
ORCID for Anthony Postle: ORCID iD orcid.org/0000-0001-7361-0756
ORCID for James S Wilkinson: ORCID iD orcid.org/0000-0003-4712-1697
ORCID for Ganapathy Senthil Murugan: ORCID iD orcid.org/0000-0002-2733-3273

Catalogue record

Date deposited: 07 Aug 2023 16:40
Last modified: 12 Mar 2026 03:15

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Contributors

Author: Aneesh Vincent Veluthandath ORCID iD
Author: Waseem Ahmed ORCID iD
Author: Eleanor Osborne ORCID iD
Author: Ahilanandan Dushianthan ORCID iD
Author: Jens Madsen
Author: Howard W. Clark
Author: Anthony Postle ORCID iD
Author: James S Wilkinson ORCID iD
Author: Ganapathy Senthil Murugan ORCID iD

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