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Vibrational spectroscopy for rapid bedside medical diagnosis

Vibrational spectroscopy for rapid bedside medical diagnosis
Vibrational spectroscopy for rapid bedside medical diagnosis
Vibrational spectroscopy, in the form of Raman and Mid-IR spectroscopies, is a powerful, label-free technique that can identify and quantify individual components of a complex chemical mixture which makes it ideal for analysis of biosamples. Vibrational spectroscopic measurements are quick, simple and easy to perform, making the screening rapid and can be employed for the diagnosis of multiple conditions at once. We explore the use of vibrational spectroscopy for rapid point of care diagnosis. As an example, we study the diagnosis of neonatal respiratory distress syndrome of preterm babies. We are developing on-chip spectroscopy using low-cost and highly sensitive disposable chips. Together with machine learning, it will further simplify biomarker detection in the critical care for rapid and early diagnosis of disease.
Veluthandath, Aneesh Vincent
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Ahmed, Waseem
4326b5dd-ca37-4ea0-bd27-294f2ef011e6
Osborne, Eleanor Louisa
02a010d9-0022-4886-9862-84317076adc2
Dushianthan, Ahilanandan
013692a2-cf26-4278-80bd-9d8fcdb17751
Madsen, Jens
3a6a1da5-83bd-4fdb-9786-bfd46aed8b1d
Clark, Howard W.
d237bb0a-ab8f-4b97-8ad2-bbfe73314260
Postle, Anthony
0fa17988-b4a0-4cdc-819a-9ae15c5dad66
Wilkinson, James S
73483cf3-d9f2-4688-9b09-1c84257884ca
Murugan, Ganapathy Senthil
a867686e-0535-46cc-ad85-c2342086b25b
Veluthandath, Aneesh Vincent
6a183413-e10f-4374-bc64-a33bf7fd9cfa
Ahmed, Waseem
4326b5dd-ca37-4ea0-bd27-294f2ef011e6
Osborne, Eleanor Louisa
02a010d9-0022-4886-9862-84317076adc2
Dushianthan, Ahilanandan
013692a2-cf26-4278-80bd-9d8fcdb17751
Madsen, Jens
3a6a1da5-83bd-4fdb-9786-bfd46aed8b1d
Clark, Howard W.
d237bb0a-ab8f-4b97-8ad2-bbfe73314260
Postle, Anthony
0fa17988-b4a0-4cdc-819a-9ae15c5dad66
Wilkinson, James S
73483cf3-d9f2-4688-9b09-1c84257884ca
Murugan, Ganapathy Senthil
a867686e-0535-46cc-ad85-c2342086b25b

Veluthandath, Aneesh Vincent, Ahmed, Waseem, Osborne, Eleanor Louisa, Dushianthan, Ahilanandan, Madsen, Jens, Clark, Howard W., Postle, Anthony, Wilkinson, James S and Murugan, Ganapathy Senthil (2023) Vibrational spectroscopy for rapid bedside medical diagnosis. Photonics 2023, Indian Institute of Science, Bangalore, India. 05 - 08 Jul 2023. 4 pp .

Record type: Conference or Workshop Item (Paper)

Abstract

Vibrational spectroscopy, in the form of Raman and Mid-IR spectroscopies, is a powerful, label-free technique that can identify and quantify individual components of a complex chemical mixture which makes it ideal for analysis of biosamples. Vibrational spectroscopic measurements are quick, simple and easy to perform, making the screening rapid and can be employed for the diagnosis of multiple conditions at once. We explore the use of vibrational spectroscopy for rapid point of care diagnosis. As an example, we study the diagnosis of neonatal respiratory distress syndrome of preterm babies. We are developing on-chip spectroscopy using low-cost and highly sensitive disposable chips. Together with machine learning, it will further simplify biomarker detection in the critical care for rapid and early diagnosis of disease.

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More information

Published date: 5 July 2023
Venue - Dates: Photonics 2023, Indian Institute of Science, Bangalore, India, 2023-07-05 - 2023-07-08

Identifiers

Local EPrints ID: 480595
URI: http://eprints.soton.ac.uk/id/eprint/480595
PURE UUID: 28af8796-eddf-4c6d-94f8-eb554b7db183
ORCID for Aneesh Vincent Veluthandath: ORCID iD orcid.org/0000-0003-4306-6723
ORCID for Ahilanandan Dushianthan: ORCID iD orcid.org/0000-0002-0165-3359
ORCID for Anthony Postle: ORCID iD orcid.org/0000-0001-7361-0756
ORCID for James S Wilkinson: ORCID iD orcid.org/0000-0003-4712-1697
ORCID for Ganapathy Senthil Murugan: ORCID iD orcid.org/0000-0002-2733-3273

Catalogue record

Date deposited: 07 Aug 2023 16:40
Last modified: 27 Feb 2024 03:07

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Contributors

Author: Aneesh Vincent Veluthandath ORCID iD
Author: Waseem Ahmed
Author: Eleanor Louisa Osborne
Author: Ahilanandan Dushianthan ORCID iD
Author: Jens Madsen
Author: Howard W. Clark
Author: Anthony Postle ORCID iD
Author: Ganapathy Senthil Murugan ORCID iD

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