READ ME File For 'Summary statistics for Fathers’ preconception smoking and offspring DNA methylation: A two generation study'

Dataset DOI: 10.5258/SOTON/D2566

Date that the file was created: March, 2023

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GENERAL INFORMATION
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ReadMe Author: Dr. Negusse Tadesse Kitaba, University of Southampton 0000-0001-7518-9096

Date of data production: 17/3/2023


Related projects: RHINESSA Study
https://helse-bergen.no/fag-og-forsking/forsking/rhinessa/rhinessa-english


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SHARING/ACCESS INFORMATION
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Licenses/restrictions placed on the data, or limitations of reuse: CC-BY

Recommended citation for the data:

This dataset supports the publication:
AUTHORS:Negusse T Kitaba1*, Gerd Toril Mørkve Knudsen2,3*, Ane Johannessen4, Faisal I. Rezwan5, Andrei Malinovschi6, Anna Oudin7, Bryndis Benediktsdottir8,9, David Martino10, Francisco Javier Callejas González11, Leopoldo Palacios Gómez12, Mathias Holm13, Nils Oskar Jõgi2,3, Shyamali C Dharmage14, Svein Magne Skulstad3, Sarah H Watkins15, Matthew Suderman15, Francisco Gómez-Real2,16, Vivi Schlünssen17,18, Cecilie Svanes3,4, John W. Holloway1
TITLE:‘Fathers’ preconception smoking and offspring DNA methylation: A two generation study’
JOURNAL:Clinical Epigenetics
PAPER DOI IF KNOWN:


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DATA & FILE OVERVIEW
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This dataset contains:

1.	father_smoke15_preconception.xlsx 
Summary statistics for Epigenome association study for 304 Rhinessa offspring to comparing father’s start smoking before 15(N=64) vs never smoked(N=240). 

2.	fathersmoke_preconception.xlsx
Summary statistics for Epigenome Association Study for 875 Rhinessa offspring to comparing father preconception smoked (N=547) vs never smoked(N=328). 

3.	mother_smoking.xlsx
Summary statistics for Epigenome Association Study for 875 Rhinessa offspring to comparing mother preconception smoked (N=263) vs never smoked(N=612). 

4.	Personal_offsmoking.xlsx
Summary statistics for Epigenome Association Study for 875 Rhinessa offspring to comparing offspring own smoked (N=240) vs never smoked(N=635). 

METHODOLOGICAL INFORMATION

All methodological information is described in the methodology part of the manuscript.