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MULTI-X, a State-of-the-Art Cloud-Based Ecosystem for biomedical research

MULTI-X, a State-of-the-Art Cloud-Based Ecosystem for biomedical research
MULTI-X, a State-of-the-Art Cloud-Based Ecosystem for biomedical research

With the exponential growth of clinical data, and the fast development of AI technologies, researchers are facing unprecedented challenges in managing data storage, scalable processing, and analysis capabilities for heterogeneous multisourced datasets. Beyond the complexity of executing data-intensive workflows over large-scale distributed data, the reproducibility of computed results is of paramount importance to validate scientific discoveries. In this paper, we present MULTIX, a cross-domain research-oriented platform, designed for collaborative and reproducible science. This cloud-based framework simplifies the logistical challenges of implementing data analytics and AI solutions by providing pre-configured environments with ad-hoc scalable computing resources and secure distributed storage, to efficiently build, test, share and reproduce scientific pipelines. An exemplary use-case in the area of cardiac image analysis will be presented together with the practical application of the platform for the analysis of 20.000 subjects of the UK-Biobank database.

biomedical informatics, cloud computing, population analysis, precision medicine
1726-1733
IEEE
De Vila, Milton Hoz
a0b66415-5016-48c2-ada3-841bb5582789
Attar, Rahman
f5efd538-042a-4647-9d46-1370d3049b72
Pereanez, Marco
c050686a-fe7d-4eb7-8ee7-54b2e993d590
Frangi, Alejandro F.
35127be7-3586-4fff-a4a2-bb79cc228141
Schmidt, Harald
Griol, David
Wang, Haiying
Baumbach, Jan
Zheng, Huiru
Callejas, Zoraida
Hu, Xiaohua
Dickerson, Julie
Zhang, Le
De Vila, Milton Hoz
a0b66415-5016-48c2-ada3-841bb5582789
Attar, Rahman
f5efd538-042a-4647-9d46-1370d3049b72
Pereanez, Marco
c050686a-fe7d-4eb7-8ee7-54b2e993d590
Frangi, Alejandro F.
35127be7-3586-4fff-a4a2-bb79cc228141
Schmidt, Harald
Griol, David
Wang, Haiying
Baumbach, Jan
Zheng, Huiru
Callejas, Zoraida
Hu, Xiaohua
Dickerson, Julie
Zhang, Le

De Vila, Milton Hoz, Attar, Rahman, Pereanez, Marco and Frangi, Alejandro F. (2019) MULTI-X, a State-of-the-Art Cloud-Based Ecosystem for biomedical research. Schmidt, Harald, Griol, David, Wang, Haiying, Baumbach, Jan, Zheng, Huiru, Callejas, Zoraida, Hu, Xiaohua, Dickerson, Julie and Zhang, Le (eds.) In Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. IEEE. pp. 1726-1733 . (doi:10.1109/BIBM.2018.8621317).

Record type: Conference or Workshop Item (Paper)

Abstract

With the exponential growth of clinical data, and the fast development of AI technologies, researchers are facing unprecedented challenges in managing data storage, scalable processing, and analysis capabilities for heterogeneous multisourced datasets. Beyond the complexity of executing data-intensive workflows over large-scale distributed data, the reproducibility of computed results is of paramount importance to validate scientific discoveries. In this paper, we present MULTIX, a cross-domain research-oriented platform, designed for collaborative and reproducible science. This cloud-based framework simplifies the logistical challenges of implementing data analytics and AI solutions by providing pre-configured environments with ad-hoc scalable computing resources and secure distributed storage, to efficiently build, test, share and reproduce scientific pipelines. An exemplary use-case in the area of cardiac image analysis will be presented together with the practical application of the platform for the analysis of 20.000 subjects of the UK-Biobank database.

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More information

Published date: 21 January 2019
Additional Information: Funding Information: VIII. ACKNOWLEDGMENT This work was supported in part by the European Research Council (Back-UP, ID 777090). Our thanks to Amazon Company for funding this research through AWS Research Grant (2018-2019). Publisher Copyright: © 2018 IEEE.
Venue - Dates: 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018, , Madrid, Spain, 2018-12-03 - 2018-12-06
Keywords: biomedical informatics, cloud computing, population analysis, precision medicine

Identifiers

Local EPrints ID: 480716
URI: http://eprints.soton.ac.uk/id/eprint/480716
PURE UUID: 07ae98a8-5001-45ca-a7f9-f2e18ee50e5f

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Date deposited: 08 Aug 2023 16:55
Last modified: 17 Mar 2024 13:18

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Contributors

Author: Milton Hoz De Vila
Author: Rahman Attar
Author: Marco Pereanez
Author: Alejandro F. Frangi
Editor: Harald Schmidt
Editor: David Griol
Editor: Haiying Wang
Editor: Jan Baumbach
Editor: Huiru Zheng
Editor: Zoraida Callejas
Editor: Xiaohua Hu
Editor: Julie Dickerson
Editor: Le Zhang

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