Content of Health Economics Analysis Plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey
Content of Health Economics Analysis Plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey
Objectives: Health Economics Analysis Plans (HEAPs) currently lack consistency, with uncertainty surrounding appropriate content. We aimed to develop a list of essential items that should be included in HEAPs for economic evaluations conducted alongside randomized trials.
Methods: a list of potential items for inclusion was developed by examining existing HEAPs. An electronic Delphi survey was conducted among professional health economists. Respondents were asked to rate potential items from 1 (least important) to 9 (most important), suggest additional items, and comment on proposed items (round 1). A second survey (round 2) was emailed to participants, including the participant's own scores from round 1 along with summary results from the whole panel; participants were asked to rerate each item. Consensus criteria for inclusion in the final list were predefined as >70% of participants rating an item 7-9 and <15% rating it 1-3 after round 2. A final item selection meeting was held to scrutinize the results and adjudicate on items lacking consensus.
Results: 62 participants completed round 1 of the survey. The initial list included 72 potential items; all 72 were carried forward to round 2, and no new items were added. 48 round 1 respondents (77.4%) completed round 2 and reached consensus on 53 items. At the final meeting, the expert panel (n = 9) agreed that 58 items should be included in the essential list, moved 9 items to an optional list, and dropped 5 items.
Conclusions: via expert consensus opinion, this study identified 58 items that are considered essential in a HEAP.
Consensus, Cost-Benefit Analysis/methods, Delphi Technique, Economics, Humans, Randomized Controlled Trials as Topic, Surveys and Questionnaires
539-547
Thorn, Joanna C.
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Brookes, Sara T.
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Noble, Sian M.
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Dritsaki, Melina
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Gray, Ewan
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Hughes, Dyfrig A.
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Mihaylova, Borislava
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Petrou, Stavros
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Ridyard, Colin
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Sach, Tracey
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Wilson, Edward C.F.
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Wordsworth, Sarah
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Hollingworth, William
404d4c1e-3911-4e9f-8be1-1436b4b98713
Thorn, Joanna C.
e09abbe6-3317-4966-9d95-865b5c95d469
Brookes, Sara T.
ffd7dc65-ac9a-456e-bc9c-dfee06239835
Noble, Sian M.
d795f66c-53ef-4f4d-9d35-d4fe2a4484a0
Dritsaki, Melina
85694ebb-89c1-4c1e-8107-26c3d7b96e4b
Gray, Ewan
640f76cd-997b-4a8d-8690-081ffdcd7d01
Hughes, Dyfrig A.
2f167dac-52de-4dd8-ad9e-24688b09f629
Mihaylova, Borislava
aacfabe0-8ad6-4134-b9ed-fa90ba2f7fda
Petrou, Stavros
5ee930f5-99db-4fb8-b401-95584cff0e20
Ridyard, Colin
d7f38103-02ec-4034-b331-dd57bd36147a
Sach, Tracey
5c09256f-ebed-4d14-853a-181f6c92d6f2
Wilson, Edward C.F.
aa0c5c9e-1464-4be2-850c-17a51cc4bcd9
Wordsworth, Sarah
d061a0ab-fad7-4842-96af-26e9efe20fb1
Hollingworth, William
404d4c1e-3911-4e9f-8be1-1436b4b98713
Thorn, Joanna C., Davies, Charlotte F., Brookes, Sara T., Noble, Sian M., Dritsaki, Melina, Gray, Ewan, Hughes, Dyfrig A., Mihaylova, Borislava, Petrou, Stavros, Ridyard, Colin, Sach, Tracey, Wilson, Edward C.F., Wordsworth, Sarah and Hollingworth, William
(2020)
Content of Health Economics Analysis Plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey.
Value in Health, 24 (4), .
(doi:10.1016/j.jval.2020.10.002).
Abstract
Objectives: Health Economics Analysis Plans (HEAPs) currently lack consistency, with uncertainty surrounding appropriate content. We aimed to develop a list of essential items that should be included in HEAPs for economic evaluations conducted alongside randomized trials.
Methods: a list of potential items for inclusion was developed by examining existing HEAPs. An electronic Delphi survey was conducted among professional health economists. Respondents were asked to rate potential items from 1 (least important) to 9 (most important), suggest additional items, and comment on proposed items (round 1). A second survey (round 2) was emailed to participants, including the participant's own scores from round 1 along with summary results from the whole panel; participants were asked to rerate each item. Consensus criteria for inclusion in the final list were predefined as >70% of participants rating an item 7-9 and <15% rating it 1-3 after round 2. A final item selection meeting was held to scrutinize the results and adjudicate on items lacking consensus.
Results: 62 participants completed round 1 of the survey. The initial list included 72 potential items; all 72 were carried forward to round 2, and no new items were added. 48 round 1 respondents (77.4%) completed round 2 and reached consensus on 53 items. At the final meeting, the expert panel (n = 9) agreed that 58 items should be included in the essential list, moved 9 items to an optional list, and dropped 5 items.
Conclusions: via expert consensus opinion, this study identified 58 items that are considered essential in a HEAP.
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PIIS1098301520344442
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e-pub ahead of print date: 28 November 2020
Additional Information:
Copyright © 2020 ISPOR–The Professional Society for Health Economics and Outcomes Research. Published by Elsevier Inc. All rights reserved.
Keywords:
Consensus, Cost-Benefit Analysis/methods, Delphi Technique, Economics, Humans, Randomized Controlled Trials as Topic, Surveys and Questionnaires
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Local EPrints ID: 480855
URI: http://eprints.soton.ac.uk/id/eprint/480855
ISSN: 1098-3015
PURE UUID: 970f8957-0a7b-4efe-81ef-baabf95e81a8
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Date deposited: 10 Aug 2023 16:39
Last modified: 10 Sep 2024 02:07
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Contributors
Author:
Joanna C. Thorn
Author:
Charlotte F. Davies
Author:
Sara T. Brookes
Author:
Sian M. Noble
Author:
Melina Dritsaki
Author:
Ewan Gray
Author:
Dyfrig A. Hughes
Author:
Borislava Mihaylova
Author:
Stavros Petrou
Author:
Colin Ridyard
Author:
Tracey Sach
Author:
Edward C.F. Wilson
Author:
Sarah Wordsworth
Author:
William Hollingworth
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