Cost-effectiveness of a preferred intensity exercise programme for young people with depression compared with treatment as usual: an economic evaluation alongside a clinical trial in the UK
Cost-effectiveness of a preferred intensity exercise programme for young people with depression compared with treatment as usual: an economic evaluation alongside a clinical trial in the UK
OBJECTIVES: To assess the cost-effectiveness of preferred intensity exercise programme for young people with depression compared with a treatment as usual control group.
DESIGN: A 'within trial' cost-effectiveness and cost-utility analysis conducted alongside a randomised controlled trial. The perspective of the analysis was the UK National Health Service and social services.
SETTING: The intervention was provided in a community leisure centre setting.
PARTICIPANTS: 86 young people aged 14-17 years attending Tier 2 and Tier 3 CAMHS (Child and Adolescent Mental Health Services) outpatient services presenting with depression.
INTERVENTIONS: The intervention comprised 12 separate sessions of circuit training over a 6-week period. Sessions were supervised by a qualified exercise therapist. Participants also received treatment as usual. The comparator group received treatment as usual.
RESULTS: We found improvements in the Children's Depression Inventory-2 (CDI-2) and estimated cost-effectiveness at £61 per point improvement in CDI-2 for the exercise group compared with control. We found no evidence that the exercise intervention led to differences in quality-adjusted life years (QALY). QALYs were estimated using the EQ-5D-5L (5-level version of EuroQol-5 dimension).
CONCLUSIONS: There is evidence that exercise can be an effective intervention for adolescents with depression and the current study shows that preferred intensity exercise could also represent a cost-effective intervention in terms of the CDI-2.
TRIAL REGISTRATION NUMBER: NCT01474837.
Adolescent, Cost-Benefit Analysis, Depression/therapy, Exercise Therapy/economics, Female, Humans, Male, Quality of Life, Quality-Adjusted Life Years, Single-Blind Method, United Kingdom
Turner, David
407ea6bc-44cc-4afd-927d-ea953190e60a
Carter, Tim
26d1e2f4-7118-42ee-ae2f-8f36d83198d3
Sach, Tracey
5c09256f-ebed-4d14-853a-181f6c92d6f2
Guo, Boliang
7d5abf87-3b9a-46e8-a028-814f2e7a5324
Callaghan, Patrick
cb5bb94e-19bf-47ca-bfc3-d676ac81dea8
26 November 2017
Turner, David
407ea6bc-44cc-4afd-927d-ea953190e60a
Carter, Tim
26d1e2f4-7118-42ee-ae2f-8f36d83198d3
Sach, Tracey
5c09256f-ebed-4d14-853a-181f6c92d6f2
Guo, Boliang
7d5abf87-3b9a-46e8-a028-814f2e7a5324
Callaghan, Patrick
cb5bb94e-19bf-47ca-bfc3-d676ac81dea8
Turner, David, Carter, Tim, Sach, Tracey, Guo, Boliang and Callaghan, Patrick
(2017)
Cost-effectiveness of a preferred intensity exercise programme for young people with depression compared with treatment as usual: an economic evaluation alongside a clinical trial in the UK.
BMJ Open, 7 (11), [e016211].
(doi:10.1136/bmjopen-2017-016211).
Abstract
OBJECTIVES: To assess the cost-effectiveness of preferred intensity exercise programme for young people with depression compared with a treatment as usual control group.
DESIGN: A 'within trial' cost-effectiveness and cost-utility analysis conducted alongside a randomised controlled trial. The perspective of the analysis was the UK National Health Service and social services.
SETTING: The intervention was provided in a community leisure centre setting.
PARTICIPANTS: 86 young people aged 14-17 years attending Tier 2 and Tier 3 CAMHS (Child and Adolescent Mental Health Services) outpatient services presenting with depression.
INTERVENTIONS: The intervention comprised 12 separate sessions of circuit training over a 6-week period. Sessions were supervised by a qualified exercise therapist. Participants also received treatment as usual. The comparator group received treatment as usual.
RESULTS: We found improvements in the Children's Depression Inventory-2 (CDI-2) and estimated cost-effectiveness at £61 per point improvement in CDI-2 for the exercise group compared with control. We found no evidence that the exercise intervention led to differences in quality-adjusted life years (QALY). QALYs were estimated using the EQ-5D-5L (5-level version of EuroQol-5 dimension).
CONCLUSIONS: There is evidence that exercise can be an effective intervention for adolescents with depression and the current study shows that preferred intensity exercise could also represent a cost-effective intervention in terms of the CDI-2.
TRIAL REGISTRATION NUMBER: NCT01474837.
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Published date: 26 November 2017
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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Keywords:
Adolescent, Cost-Benefit Analysis, Depression/therapy, Exercise Therapy/economics, Female, Humans, Male, Quality of Life, Quality-Adjusted Life Years, Single-Blind Method, United Kingdom
Identifiers
Local EPrints ID: 480859
URI: http://eprints.soton.ac.uk/id/eprint/480859
ISSN: 2044-6055
PURE UUID: 238c8afd-7e3b-4f00-8ab8-b6990db6828f
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Date deposited: 10 Aug 2023 16:39
Last modified: 17 Mar 2024 04:20
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Contributors
Author:
David Turner
Author:
Tim Carter
Author:
Tracey Sach
Author:
Boliang Guo
Author:
Patrick Callaghan
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