All-fiberized 1840-nm femtosecond thulium fiber laser for label-free nonlinear microscopy
All-fiberized 1840-nm femtosecond thulium fiber laser for label-free nonlinear microscopy
We report an all-fiberized 1840-nm thulium-fiber-laser source, comprising a dissipative-soliton mode-locked seed laser and a chirped-pulse-amplification system for label-free biological imaging through nonlinear microscopy. The mode-locked thulium fiber laser generated dissipative-soliton pulses with a pre-chirped duration of 7 ps and pulse energy of 1 nJ. A chirped-pulse fiber-amplification system employing an in-house-fabricated, short-length, single-mode, high-absorption, thulium fiber delivered pulses with energies up to 105 nJ. The pulses were capable of being compressed to 416 fs by passing through a grating pair. Imaging of mouse tissue and human bone samples was demonstrated using this source via third-harmonic generation microscopy.
4520-4530
Xu, Duanyang
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Bourdakos, Konstantinos
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Crisford, Anna
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Johnson, Peter B.
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Abughazaleh, Ibrahim
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Srisamran, Panuwat
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Oreffo, Richard
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Mahajan, Sumeet
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Richardson, David
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Xu, Lin
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1 September 2023
Xu, Duanyang
fa113964-baa4-41c9-b11f-b4879d001cf9
Bourdakos, Konstantinos
83f6fc3a-db12-476b-9a78-4aad8756f82f
Crisford, Anna
135675e1-a172-4d93-989b-93d1efb022c3
Johnson, Peter B.
01e8bf5b-9ab6-4403-8281-93879dfdf084
Abughazaleh, Ibrahim
73ee2e1a-fdf0-473c-8657-675ae7d73885
Srisamran, Panuwat
5b98bcfa-e3a3-415d-89a4-a2fc90cef328
Oreffo, Richard
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Mahajan, Sumeet
b131f40a-479e-4432-b662-19d60d4069e9
Richardson, David
ebfe1ff9-d0c2-4e52-b7ae-c1b13bccdef3
Xu, Lin
b887cecd-d21e-49f4-9b45-6909a7369e84
Xu, Duanyang, Bourdakos, Konstantinos, Crisford, Anna, Johnson, Peter B., Abughazaleh, Ibrahim, Srisamran, Panuwat, Oreffo, Richard, Mahajan, Sumeet, Richardson, David and Xu, Lin
(2023)
All-fiberized 1840-nm femtosecond thulium fiber laser for label-free nonlinear microscopy.
Biomedical Optics Express, 14 (9), .
(doi:10.1364/BOE.495879).
Abstract
We report an all-fiberized 1840-nm thulium-fiber-laser source, comprising a dissipative-soliton mode-locked seed laser and a chirped-pulse-amplification system for label-free biological imaging through nonlinear microscopy. The mode-locked thulium fiber laser generated dissipative-soliton pulses with a pre-chirped duration of 7 ps and pulse energy of 1 nJ. A chirped-pulse fiber-amplification system employing an in-house-fabricated, short-length, single-mode, high-absorption, thulium fiber delivered pulses with energies up to 105 nJ. The pulses were capable of being compressed to 416 fs by passing through a grating pair. Imaging of mouse tissue and human bone samples was demonstrated using this source via third-harmonic generation microscopy.
Text
boe-14-9-4520
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More information
Accepted/In Press date: 1 August 2023
e-pub ahead of print date: 9 August 2023
Published date: 1 September 2023
Additional Information:
Funding Information:
Funding. Engineering and Physical Sciences Research Council (EP/P030181/1, EP/T020997/1, EP/V038036/1).
Publisher Copyright:
© 2023 OSA - The Optical Society. All rights reserved.
Identifiers
Local EPrints ID: 481532
URI: http://eprints.soton.ac.uk/id/eprint/481532
ISSN: 2156-7085
PURE UUID: 4418d44f-3150-4904-b6bd-1fdd8a4fac78
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Date deposited: 31 Aug 2023 16:52
Last modified: 18 Mar 2024 03:32
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Contributors
Author:
Duanyang Xu
Author:
Konstantinos Bourdakos
Author:
Peter B. Johnson
Author:
Ibrahim Abughazaleh
Author:
Panuwat Srisamran
Author:
Lin Xu
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