The association of DNA methylation at birth with adolescent asthma is mediated by atopy

Accepted/In Press date: 17 August 2023

e-pub ahead of print date: 28 August 2023

Published date: November 2023

Additional Information: Funding Information: This study was supported by the National Institutes of Health research fund R01AI121226 (MPI: H Zhang and JW Holloway). The methylation data generation in newborns was supported by R01HL132321 (PI: W Karmaus). The Isle of Wight Birth Cohort assessments have been supported by the National Institutes of Health USA (Grant no. R01 HL082925, H. Arshad), Asthma UK (Grant no. 364. S.H. Arshad), and the David Hide Asthma and Allergy Research Trust. None of the sponsors were involved in study design; collection, analysis, and interpretation of data; the writing of the manuscript; and the decision to submit the manuscript for publication. The authors are thankful to all the IOWBC participants and greatly appreciate the support of High‐Performance Computing facility at the University of Memphis. The UK Medical Research Council and Wellcome (Grant ref: 217065/Z/19/Z) and the University of Bristol provided core support for ALSPAC. A comprehensive list of grant funding is available on the ALSPAC website ( http://www.bristol.ac.uk/alspac/external/documents/grant‐acknowledgements.pdf (accessed on 12 August 2019). The generation of methylation array data was specifically funded by NIH R01AI121226, R01AI091905, BBSRC BBI025751/1 and BB/I025263/1, MRC MC_UU_12013/1, MC_UU_12013/2, and MC_UU_12013/8. Funding Information: This study was supported by the National Institutes of Health research fund R01AI121226 (MPI: H Zhang and JW Holloway). The methylation data generation in newborns was supported by R01HL132321 (PI: W Karmaus). The Isle of Wight Birth Cohort assessments have been supported by the National Institutes of Health USA (Grant no. R01 HL082925, H. Arshad), Asthma UK (Grant no. 364. S.H. Arshad), and the David Hide Asthma and Allergy Research Trust. None of the sponsors were involved in study design; collection, analysis, and interpretation of data; the writing of the manuscript; and the decision to submit the manuscript for publication. The authors are thankful to all the IOWBC participants and greatly appreciate the support of High-Performance Computing facility at the University of Memphis. The UK Medical Research Council and Wellcome (Grant ref: 217065/Z/19/Z) and the University of Bristol provided core support for ALSPAC. A comprehensive list of grant funding is available on the ALSPAC website (http://www.bristol.ac.uk/alspac/external/documents/grant-acknowledgements.pdf (accessed on 12 August 2019). The generation of methylation array data was specifically funded by NIH R01AI121226, R01AI091905, BBSRC BBI025751/1 and BB/I025263/1, MRC MC_UU_12013/1, MC_UU_12013/2, and MC_UU_12013/8.

Local EPrints ID: 481590

URI: http://eprints.soton.ac.uk/id/eprint/481590

DOI: doi:10.1111/cea.14386

ISSN: 0954-7894

PURE UUID: 231b1a22-8acd-44ef-bd7f-fcc14ac4f7dd

ORCID for John W. Holloway: orcid.org/0000-0001-9998-0464

Date deposited: 04 Sep 2023 16:47

Last modified: 18 Mar 2024 02:47