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Liquid metal-based amalgamation-assisted lithography for fabrication of complex channels with diverse structures and configurations

Liquid metal-based amalgamation-assisted lithography for fabrication of complex channels with diverse structures and configurations
Liquid metal-based amalgamation-assisted lithography for fabrication of complex channels with diverse structures and configurations

Numerous lab-on-a-chip applications benefit from channels with complex structures and configurations in the areas of tissue engineering and clinical diagnostics. The current fabrication approaches require time-consuming, complicated processes and bulky, expensive facilities. In this work, we propose a novel method for the fabrication of complex channels with the assistance of amalgamation of liquid metal with copper tape. This new technique enables the rapid fabrication of liquid metal molds with various dimensions and diverse structures. Two proof-of-concept experiments were conducted to verify the utilization of this method. First, the channel replicated from the liquid metal mold is used to enhance the mixing performance of liquids flowing through the channel. Second, a channel with a semicircular cross-section is fabricated to achieve 3D focusing in a simple way. This proposed technique can be readily used for fabricating complex channels for a wide range of applications.

1473-0197
785-792
Yan, Sheng
1cf2968c-1639-4c47-a90b-481b86c441cb
Li, Yuxing
5e0dfa2f-1857-4c16-b79e-7becedb5eb55
Zhao, Qianbin
4e956b7f-4fb6-42fa-9a3b-b9a7c3703493
Yuan, Dan
76b9b77e-dda5-4682-8db0-75bfad1d1258
Yun, Guolin
240c3dc9-c224-41c0-8740-de165d1eb90b
Zhang, Jun
a4628c00-1e1c-4729-8d8a-e7619a2c1edf
Wen, Weijia
8077209d-a633-4e3c-b0b6-16ddddb7a153
Tang, Shi Yang
1d0f15c6-2a3e-4bad-a3d8-fc267db93ed4
Li, Weihua
e2555036-0e48-425a-afeb-db6ffba5238e
Yan, Sheng
1cf2968c-1639-4c47-a90b-481b86c441cb
Li, Yuxing
5e0dfa2f-1857-4c16-b79e-7becedb5eb55
Zhao, Qianbin
4e956b7f-4fb6-42fa-9a3b-b9a7c3703493
Yuan, Dan
76b9b77e-dda5-4682-8db0-75bfad1d1258
Yun, Guolin
240c3dc9-c224-41c0-8740-de165d1eb90b
Zhang, Jun
a4628c00-1e1c-4729-8d8a-e7619a2c1edf
Wen, Weijia
8077209d-a633-4e3c-b0b6-16ddddb7a153
Tang, Shi Yang
1d0f15c6-2a3e-4bad-a3d8-fc267db93ed4
Li, Weihua
e2555036-0e48-425a-afeb-db6ffba5238e

Yan, Sheng, Li, Yuxing, Zhao, Qianbin, Yuan, Dan, Yun, Guolin, Zhang, Jun, Wen, Weijia, Tang, Shi Yang and Li, Weihua (2018) Liquid metal-based amalgamation-assisted lithography for fabrication of complex channels with diverse structures and configurations. Lab on a Chip, 18 (5), 785-792. (doi:10.1039/c8lc00047f).

Record type: Article

Abstract

Numerous lab-on-a-chip applications benefit from channels with complex structures and configurations in the areas of tissue engineering and clinical diagnostics. The current fabrication approaches require time-consuming, complicated processes and bulky, expensive facilities. In this work, we propose a novel method for the fabrication of complex channels with the assistance of amalgamation of liquid metal with copper tape. This new technique enables the rapid fabrication of liquid metal molds with various dimensions and diverse structures. Two proof-of-concept experiments were conducted to verify the utilization of this method. First, the channel replicated from the liquid metal mold is used to enhance the mixing performance of liquids flowing through the channel. Second, a channel with a semicircular cross-section is fabricated to achieve 3D focusing in a simple way. This proposed technique can be readily used for fabricating complex channels for a wide range of applications.

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More information

Published date: 7 March 2018
Additional Information: Funding Information: Dr. Sheng Yan is the recipient of the 2018 Endeavour Research Fellowship funded by the Australian Department of Education and Training. Dr. Shi-Yang Tang is the recipient of the Vice-Chancellor's Postdoctoral Research Fellowship funded by the University of Wollongong. Publisher Copyright: © 2018 The Royal Society of Chemistry.

Identifiers

Local EPrints ID: 481695
URI: http://eprints.soton.ac.uk/id/eprint/481695
ISSN: 1473-0197
PURE UUID: 987ad0f8-e81c-4fa3-a294-1eca9b53e6d2
ORCID for Shi Yang Tang: ORCID iD orcid.org/0000-0002-3079-8880

Catalogue record

Date deposited: 06 Sep 2023 16:49
Last modified: 06 Jun 2024 02:18

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Contributors

Author: Sheng Yan
Author: Yuxing Li
Author: Qianbin Zhao
Author: Dan Yuan
Author: Guolin Yun
Author: Jun Zhang
Author: Weijia Wen
Author: Shi Yang Tang ORCID iD
Author: Weihua Li

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