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Blood Triglyceride Monitoring with Smartphone as Electrochemical Analyzer for Cardiovascular Disease Prevention

Blood Triglyceride Monitoring with Smartphone as Electrochemical Analyzer for Cardiovascular Disease Prevention
Blood Triglyceride Monitoring with Smartphone as Electrochemical Analyzer for Cardiovascular Disease Prevention

Nowadays, cardiovascular diseases have become one of the most risks threating human being's life in the world. The early screening and efficient management of cardiovascular diseases are critically important to extend the patients' life. Blood lipid level is a key biochemical factor used to estimate the cardiovascular disease in clinical situation. Triglyceride as one important blood lipid plays an indispensable role in the blood test. On the other hand, smartphone has unprecedentedly large scale users since the last decade, which paves the wide avenue for the dissemination of smartphone-associated medical devices. In this paper, we integrated the smartphone with the Triglyceride (TG) sensory module to monitor the finger pricked whole blood TG at the point of care scale. The miniaturized electrochemical analyzer was immobilized on the main board of the smartphone which enables the smartphone work as the blood TG analyzer incorporating with the disposable electrochemical TG test strip. The blood TG measured by the medical smartphone was compared to the results obtained from the conventional bulky biochemical analyzer with acceptable accuracy, which demonstrated that the proposed medical smartphone is capable of providing a point of care analytical device for blood TC monitoring at the medical level. Its potential in cardiovascular disease prevention and management was believed to be great, since the proposed system is ultracompact, smart, cost effective, reliable, and flexible with medical data acquisition.

Cardiovascular disease estimation, electrochemical sensor, medical smartphone, point of care test, triglyceride monitoring
2168-2194
66-71
Wang, Jian
010afd88-adf6-442d-8329-64912c031eed
Huang, Xiwei
ee904345-5092-4592-b116-a2cef1a114f3
Tang, Shi Yang
1d0f15c6-2a3e-4bad-a3d8-fc267db93ed4
Shi, Gong Ming
d674d1f1-00d6-40f7-b784-026a485b3df1
Ma, Xing
e33cecd7-1a4c-4ebf-87d2-d1496a44bdd7
Guo, Jinhong
d65d7044-32c8-4028-a6b3-d221ad8bf006
Wang, Jian
010afd88-adf6-442d-8329-64912c031eed
Huang, Xiwei
ee904345-5092-4592-b116-a2cef1a114f3
Tang, Shi Yang
1d0f15c6-2a3e-4bad-a3d8-fc267db93ed4
Shi, Gong Ming
d674d1f1-00d6-40f7-b784-026a485b3df1
Ma, Xing
e33cecd7-1a4c-4ebf-87d2-d1496a44bdd7
Guo, Jinhong
d65d7044-32c8-4028-a6b3-d221ad8bf006

Wang, Jian, Huang, Xiwei, Tang, Shi Yang, Shi, Gong Ming, Ma, Xing and Guo, Jinhong (2019) Blood Triglyceride Monitoring with Smartphone as Electrochemical Analyzer for Cardiovascular Disease Prevention. IEEE Journal of Biomedical and Health Informatics, 23 (1), 66-71, [8377993]. (doi:10.1109/JBHI.2018.2845860).

Record type: Article

Abstract

Nowadays, cardiovascular diseases have become one of the most risks threating human being's life in the world. The early screening and efficient management of cardiovascular diseases are critically important to extend the patients' life. Blood lipid level is a key biochemical factor used to estimate the cardiovascular disease in clinical situation. Triglyceride as one important blood lipid plays an indispensable role in the blood test. On the other hand, smartphone has unprecedentedly large scale users since the last decade, which paves the wide avenue for the dissemination of smartphone-associated medical devices. In this paper, we integrated the smartphone with the Triglyceride (TG) sensory module to monitor the finger pricked whole blood TG at the point of care scale. The miniaturized electrochemical analyzer was immobilized on the main board of the smartphone which enables the smartphone work as the blood TG analyzer incorporating with the disposable electrochemical TG test strip. The blood TG measured by the medical smartphone was compared to the results obtained from the conventional bulky biochemical analyzer with acceptable accuracy, which demonstrated that the proposed medical smartphone is capable of providing a point of care analytical device for blood TC monitoring at the medical level. Its potential in cardiovascular disease prevention and management was believed to be great, since the proposed system is ultracompact, smart, cost effective, reliable, and flexible with medical data acquisition.

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More information

Published date: January 2019
Additional Information: Funding Information: Manuscript received January 12, 2018; revised May 14, 2018; accepted June 6, 2018. Date of publication June 10, 2018; date of current version January 2, 2019. This work was financially supported by Shenzhen Peacock Innovation Project (KQJSCX20170726104623185). (Corresponding authors: Xing Ma; Jinhong Guo.) J. Wang is with School of Communication and Information Engineering, University of Electronic Science and Technology of China, Chengdu 611731, China (e-mail:,wangjian3630@uestc.edu.cn). Publisher Copyright: © 2013 IEEE.
Keywords: Cardiovascular disease estimation, electrochemical sensor, medical smartphone, point of care test, triglyceride monitoring

Identifiers

Local EPrints ID: 481709
URI: http://eprints.soton.ac.uk/id/eprint/481709
ISSN: 2168-2194
PURE UUID: 7ebb1af0-a5d7-4323-8bf4-ca9ffc76d3a6
ORCID for Shi Yang Tang: ORCID iD orcid.org/0000-0002-3079-8880

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Date deposited: 06 Sep 2023 16:50
Last modified: 18 Mar 2024 04:13

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Contributors

Author: Jian Wang
Author: Xiwei Huang
Author: Shi Yang Tang ORCID iD
Author: Gong Ming Shi
Author: Xing Ma
Author: Jinhong Guo

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