Liquid metal droplet robot
Liquid metal droplet robot
Liquid metal (LM) droplets made from gallium-based alloys exhibit excellent biomimetic locomotion and deformation capabilities under external stimulating fields and have presented potentials in a variety of applications. However, its application in robotics is presently hampered by limited maneuverability in two-dimensional (2D) space and weak cargo carrying capacity. Here, we propose a composite liquid metal droplet robot (LMDR) which appears as a LM droplet but exhibits an extraordinary actuating performance in 3D space. The LMDR is fabricated by assembling a hollow and spherical-shaped magnetic internal framework (IF) into a LM droplet, and the IF can be disassembled from the LM droplet with the application of an external magnetic field. The maneuver of the LMDR is realized using the interplay of electric and magnetic fields, and complex actuation especially jumping to avoid obstacles, climbing steep slopes, and rotating its body to the desired posture can be achieved. The hollow IF within the LMDR has a cargo carrying capacity and we demonstrate a proof-of-concept experiment to show the transportation and controlled release of a chemical indicator using the LMDR. More importantly, an in vitro targeted drug delivery and therapy trial to treat breast cancer cells (4T1) with a drug loaded LMDR is also successfully performed. The demonstrated capabilities of the LMDR present a promising potential in developing future targeted drug delivery and soft robotic systems with high controllability and multi-functionalities.
3D actuation, EGaIn, Liquid metal, Soft robotics, Targeted drug delivery
Li, Fangxia
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Shu, Jian
10c82f94-8f99-4785-b33f-fa20484344fd
Zhang, Leran
ad0a5941-c87f-46ba-9f4b-badd4784bdbc
Yang, Nailin
c5544724-9421-4b75-ba17-a5d34db3589c
Xie, Jie
95f5ab65-2bf0-4a5d-b0e5-1bfa27e1cb34
Li, Xiangpeng
73f32905-ad7c-4ce3-93a4-78237b98f4fb
Cheng, Liang
3e5c1edf-17d3-4f54-9130-995bc16dd880
Kuang, Shaolong
9661f7da-26f6-4d10-85ef-8e0d1204548b
Tang, Shi Yang
1d0f15c6-2a3e-4bad-a3d8-fc267db93ed4
Zhang, Shiwu
da008f91-71fa-42fb-879e-68b91429e1d6
Li, Weihua
e2555036-0e48-425a-afeb-db6ffba5238e
Sun, Lining
e4660e06-1315-4059-985f-2cb1e50c5fc8
Sun, Dong
31f20fcf-e383-441d-8a91-41f96adce55b
June 2020
Li, Fangxia
a3d24e25-2342-4b61-92f7-6afc1ae815ce
Shu, Jian
10c82f94-8f99-4785-b33f-fa20484344fd
Zhang, Leran
ad0a5941-c87f-46ba-9f4b-badd4784bdbc
Yang, Nailin
c5544724-9421-4b75-ba17-a5d34db3589c
Xie, Jie
95f5ab65-2bf0-4a5d-b0e5-1bfa27e1cb34
Li, Xiangpeng
73f32905-ad7c-4ce3-93a4-78237b98f4fb
Cheng, Liang
3e5c1edf-17d3-4f54-9130-995bc16dd880
Kuang, Shaolong
9661f7da-26f6-4d10-85ef-8e0d1204548b
Tang, Shi Yang
1d0f15c6-2a3e-4bad-a3d8-fc267db93ed4
Zhang, Shiwu
da008f91-71fa-42fb-879e-68b91429e1d6
Li, Weihua
e2555036-0e48-425a-afeb-db6ffba5238e
Sun, Lining
e4660e06-1315-4059-985f-2cb1e50c5fc8
Sun, Dong
31f20fcf-e383-441d-8a91-41f96adce55b
Li, Fangxia, Shu, Jian, Zhang, Leran, Yang, Nailin, Xie, Jie, Li, Xiangpeng, Cheng, Liang, Kuang, Shaolong, Tang, Shi Yang, Zhang, Shiwu, Li, Weihua, Sun, Lining and Sun, Dong
(2020)
Liquid metal droplet robot.
Applied Materials Today, 19, [100597].
(doi:10.1016/j.apmt.2020.100597).
Abstract
Liquid metal (LM) droplets made from gallium-based alloys exhibit excellent biomimetic locomotion and deformation capabilities under external stimulating fields and have presented potentials in a variety of applications. However, its application in robotics is presently hampered by limited maneuverability in two-dimensional (2D) space and weak cargo carrying capacity. Here, we propose a composite liquid metal droplet robot (LMDR) which appears as a LM droplet but exhibits an extraordinary actuating performance in 3D space. The LMDR is fabricated by assembling a hollow and spherical-shaped magnetic internal framework (IF) into a LM droplet, and the IF can be disassembled from the LM droplet with the application of an external magnetic field. The maneuver of the LMDR is realized using the interplay of electric and magnetic fields, and complex actuation especially jumping to avoid obstacles, climbing steep slopes, and rotating its body to the desired posture can be achieved. The hollow IF within the LMDR has a cargo carrying capacity and we demonstrate a proof-of-concept experiment to show the transportation and controlled release of a chemical indicator using the LMDR. More importantly, an in vitro targeted drug delivery and therapy trial to treat breast cancer cells (4T1) with a drug loaded LMDR is also successfully performed. The demonstrated capabilities of the LMDR present a promising potential in developing future targeted drug delivery and soft robotic systems with high controllability and multi-functionalities.
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Published date: June 2020
Additional Information:
Funding Information:
This work is supported in part by grants from the National Natural Science Foundation of China under Grant Nos. 61703294 , 61873339 , 61503270 , 51828503 , a grant from National Science Foundation of Jiangsu Province under Grant No. BK20170342 , BK20190096 , a grant from China Postdoctoral Science Foundation under Grant No. 2016M590497 , and supported by the State Key Laboratory of Applied Optics . Dr. Shi-Yang Tang is the recipient of the Vice-Chancellor’s Postdoctoral Research Fellowship funded by the University of Wollongong .
Publisher Copyright:
© 2020 Elsevier Ltd
Keywords:
3D actuation, EGaIn, Liquid metal, Soft robotics, Targeted drug delivery
Identifiers
Local EPrints ID: 481721
URI: http://eprints.soton.ac.uk/id/eprint/481721
ISSN: 2352-9407
PURE UUID: 47ae3a20-5985-4a6a-9d24-ea1a9a67076d
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Date deposited: 06 Sep 2023 16:50
Last modified: 06 Jun 2024 02:18
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Contributors
Author:
Fangxia Li
Author:
Jian Shu
Author:
Leran Zhang
Author:
Nailin Yang
Author:
Jie Xie
Author:
Xiangpeng Li
Author:
Liang Cheng
Author:
Shaolong Kuang
Author:
Shi Yang Tang
Author:
Shiwu Zhang
Author:
Weihua Li
Author:
Lining Sun
Author:
Dong Sun
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