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Modular and integrated systems for nanoparticle and microparticle synthesis - a review

Modular and integrated systems for nanoparticle and microparticle synthesis - a review
Modular and integrated systems for nanoparticle and microparticle synthesis - a review

Nanoparticles (NPs) and microparticles (MPs) have been widely used in different areas of research such as materials science, energy, and biotechnology. On-demand synthesis of NPs and MPs with desired chemical and physical properties is essential for different applications. However, most of the conventional methods for producing NPs/MPs require bulky and expensive equipment, which occupies large space and generally need complex operation with dedicated expertise and labour. These limitations hinder inexperienced researchers to harness the advantages of NPs and MPs in their fields of research. When problems individual researchers accumulate, the overall interdisciplinary innovations for unleashing a wider range of directions are undermined. In recent years, modular and integrated systems are developed for resolving the ongoing dilemma. In this review, we focus on the development of modular and integrated systems that assist the production of NPs and MPs. We categorise these systems into two major groups: systems for the synthesis of (1) NPs and (2) MPs; systems for producing NPs are further divided into two sections based on top-down and bottom-up approaches. The mechanisms of each synthesis method are explained, and the properties of produced NPs/MPs are compared. Finally, we discuss existing challenges and outline the potentials for the development of modular and integrated systems.

integrated systems, microfluidics, microparticles, modularisation, nanoparticles, synthesis
0265-928X
Lu, Hongda
731b3c09-82ae-408b-8218-95b0de29f2dd
Tang, Shi Yang
1d0f15c6-2a3e-4bad-a3d8-fc267db93ed4
Yun, Guolin
240c3dc9-c224-41c0-8740-de165d1eb90b
Li, Haiyue
302d0ed3-f5fc-44cb-82cd-e003e8db07a6
Zhang, Yuxin
f858a4e3-2841-46cb-a6d7-a5230e25f467
Qiao, Ruirui
cf0ce629-af33-47c2-81c5-6d62ccf80f7e
Li, Weihua
e2555036-0e48-425a-afeb-db6ffba5238e
Lu, Hongda
731b3c09-82ae-408b-8218-95b0de29f2dd
Tang, Shi Yang
1d0f15c6-2a3e-4bad-a3d8-fc267db93ed4
Yun, Guolin
240c3dc9-c224-41c0-8740-de165d1eb90b
Li, Haiyue
302d0ed3-f5fc-44cb-82cd-e003e8db07a6
Zhang, Yuxin
f858a4e3-2841-46cb-a6d7-a5230e25f467
Qiao, Ruirui
cf0ce629-af33-47c2-81c5-6d62ccf80f7e
Li, Weihua
e2555036-0e48-425a-afeb-db6ffba5238e

Lu, Hongda, Tang, Shi Yang, Yun, Guolin, Li, Haiyue, Zhang, Yuxin, Qiao, Ruirui and Li, Weihua (2020) Modular and integrated systems for nanoparticle and microparticle synthesis - a review. Biosensors, 10 (11), [165]. (doi:10.3390/BIOS10110165).

Record type: Review

Abstract

Nanoparticles (NPs) and microparticles (MPs) have been widely used in different areas of research such as materials science, energy, and biotechnology. On-demand synthesis of NPs and MPs with desired chemical and physical properties is essential for different applications. However, most of the conventional methods for producing NPs/MPs require bulky and expensive equipment, which occupies large space and generally need complex operation with dedicated expertise and labour. These limitations hinder inexperienced researchers to harness the advantages of NPs and MPs in their fields of research. When problems individual researchers accumulate, the overall interdisciplinary innovations for unleashing a wider range of directions are undermined. In recent years, modular and integrated systems are developed for resolving the ongoing dilemma. In this review, we focus on the development of modular and integrated systems that assist the production of NPs and MPs. We categorise these systems into two major groups: systems for the synthesis of (1) NPs and (2) MPs; systems for producing NPs are further divided into two sections based on top-down and bottom-up approaches. The mechanisms of each synthesis method are explained, and the properties of produced NPs/MPs are compared. Finally, we discuss existing challenges and outline the potentials for the development of modular and integrated systems.

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More information

Published date: November 2020
Additional Information: Publisher Copyright: © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
Keywords: integrated systems, microfluidics, microparticles, modularisation, nanoparticles, synthesis

Identifiers

Local EPrints ID: 481723
URI: http://eprints.soton.ac.uk/id/eprint/481723
ISSN: 0265-928X
PURE UUID: b9b63002-b7cc-42f4-90d4-c47c2b44a47f
ORCID for Shi Yang Tang: ORCID iD orcid.org/0000-0002-3079-8880

Catalogue record

Date deposited: 06 Sep 2023 16:51
Last modified: 18 Mar 2024 04:13

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Contributors

Author: Hongda Lu
Author: Shi Yang Tang ORCID iD
Author: Guolin Yun
Author: Haiyue Li
Author: Yuxin Zhang
Author: Ruirui Qiao
Author: Weihua Li

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