Heart rate variability in children and adolescents with autism, ADHD and co-occurring autism and ADHD, during passive and active experimental conditions
Heart rate variability in children and adolescents with autism, ADHD and co-occurring autism and ADHD, during passive and active experimental conditions
Despite overlaps in clinical symptomatology, autism and ADHD may be associated with opposite autonomic arousal profiles which might partly explain altered cognitive and global functioning. We investigated autonomic arousal in 106 children/adolescents with autism, ADHD, co-occurring autism/ADHD, and neurotypical controls. Heart rate variability was recorded during resting-state, a ‘passive’ auditory oddball task and an ‘active’ response conflict task. Autistic children showed hyper-arousal during the active task, while those with ADHD showed hypo-arousal during resting-state and the passive task. Irrespective of diagnosis, children characterised by hyper-arousal showed more severe autistic symptomatology, increased anxiety and reduced global functioning than those displaying hypo-arousal, suggesting the importance of considering individual autonomic arousal profiles for differential diagnosis of autism/ADHD and when developing personalised interventions.
ADHD, Autism, Autonomic nervous system, Heart rate variability, Comorbidity, Cognitive function
4679-4691
Bellato, Alessio
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Arora, Iti
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Kochhar, Puja
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Ropar, Danielle
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Hollis, Chris
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Groom, Madeleine J.
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Bellato, Alessio
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Arora, Iti
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Kochhar, Puja
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Ropar, Danielle
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Hollis, Chris
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Groom, Madeleine J.
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Bellato, Alessio, Arora, Iti, Kochhar, Puja, Ropar, Danielle, Hollis, Chris and Groom, Madeleine J.
(2022)
Heart rate variability in children and adolescents with autism, ADHD and co-occurring autism and ADHD, during passive and active experimental conditions.
Journal of Autism and Developmental Disorders, 52 (11), .
(doi:10.1007/s10803-021-05244-w).
Abstract
Despite overlaps in clinical symptomatology, autism and ADHD may be associated with opposite autonomic arousal profiles which might partly explain altered cognitive and global functioning. We investigated autonomic arousal in 106 children/adolescents with autism, ADHD, co-occurring autism/ADHD, and neurotypical controls. Heart rate variability was recorded during resting-state, a ‘passive’ auditory oddball task and an ‘active’ response conflict task. Autistic children showed hyper-arousal during the active task, while those with ADHD showed hypo-arousal during resting-state and the passive task. Irrespective of diagnosis, children characterised by hyper-arousal showed more severe autistic symptomatology, increased anxiety and reduced global functioning than those displaying hypo-arousal, suggesting the importance of considering individual autonomic arousal profiles for differential diagnosis of autism/ADHD and when developing personalised interventions.
Text
s10803-021-05244-w
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Accepted/In Press date: 13 August 2021
e-pub ahead of print date: 30 November 2022
Keywords:
ADHD, Autism, Autonomic nervous system, Heart rate variability, Comorbidity, Cognitive function
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Local EPrints ID: 482009
URI: http://eprints.soton.ac.uk/id/eprint/482009
ISSN: 0162-3257
PURE UUID: 80ff59be-4f9b-4551-a1eb-ce52a642c564
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Date deposited: 15 Sep 2023 16:32
Last modified: 18 Mar 2024 04:16
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Contributors
Author:
Alessio Bellato
Author:
Iti Arora
Author:
Puja Kochhar
Author:
Danielle Ropar
Author:
Chris Hollis
Author:
Madeleine J. Groom
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