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The Validity and Applicability of the Revised Delirium Rating Scale (DRS-R98) for Delirium Severity Assessment in a Critical Care Setting

The Validity and Applicability of the Revised Delirium Rating Scale (DRS-R98) for Delirium Severity Assessment in a Critical Care Setting
The Validity and Applicability of the Revised Delirium Rating Scale (DRS-R98) for Delirium Severity Assessment in a Critical Care Setting

Background: delirium is a neuropsychiatric syndrome common in critical illness. Worsening delirium severity is associated with poorer clinical outcomes, yet its assessment remains under-reported with most severity assessment tools not validated for critical care. The DRS-R98 is a widely applied and validated tool. The aim of this project is to report the validation and utility of the DRS-R98 in critical illness. 

Methods: this prospective, cohort study was conducted in adults with delirium admitted to a critical care unit and predicted to stay for ≥ 24 h. We excluded patients with severe neurological or communication barriers that would have interfered with the DRS-R98 assessment. Patients were screened using a delirium detection algorithm and the Confusion Assessment Method for the Intensive Care Unit. Eligible patient informations were collected and reported to qualified assessor/s before visiting clinical areas, confirming delirium presence and undertaking DRS- R98 assessments. To assess the tool's construct validity, an intensivist completed the Clinical Global Impression-Scale (CGI-S). To calculate the inter-rater reliability (IRR) a subset of patients were simultaneously evaluated by two assessors. 

Results: we assessed 22 patients, 73% were male, with a median age of 65 years (IQR14). The DRS -R98 mean (SD) severity score was 24 (+/-7.7), total scale was 29 (+/18.0), and CGI-S 3.5 (+/11.5). Assessment duration was 90 min (+/-55) and 15 min (+/-5) for record data extraction and clinical assessment respectively. The CGI-S significantly correlated with DRS-R98 severity (r = 0.626) and total (r = 0.628) scales. The DRS-R98 Cronbach's alpha was 0.896 for severity scale and 0.886 for total scale. The inter-rater reliability (IRR) was assessed in six patients and reported an inter-correlation coefficient of 0.505 (p = 0.124) and 0.565 (p = 0.93) for the severity and total scale respectively. 

Conclusions: in critical care, the Delirium Rating Scale R98 had good construct validity, excellent internal consistency, and moderate inter-rater reliability.

critical care, delirium, intensive care, severity, validation
0885-0666
240-249
Almuhairi, Eiman Saeed
98b98f53-6995-4fc6-ae42-8897b6e216b0
Badejo, Monica
e638dc4d-a1cc-445c-a210-acd82a7d3a3a
Peer, Aneesa
f9781b2a-3674-4dc0-9d1a-4a4e63ec2346
Pitkanen, Mervi
8e63dfb1-745f-44c9-8711-c4866be3a5ea
McKenzie, Cathrine A.
ec344dee-5777-49c5-970e-6326e82c9f8c
Almuhairi, Eiman Saeed
98b98f53-6995-4fc6-ae42-8897b6e216b0
Badejo, Monica
e638dc4d-a1cc-445c-a210-acd82a7d3a3a
Peer, Aneesa
f9781b2a-3674-4dc0-9d1a-4a4e63ec2346
Pitkanen, Mervi
8e63dfb1-745f-44c9-8711-c4866be3a5ea
McKenzie, Cathrine A.
ec344dee-5777-49c5-970e-6326e82c9f8c

Almuhairi, Eiman Saeed, Badejo, Monica, Peer, Aneesa, Pitkanen, Mervi and McKenzie, Cathrine A. (2023) The Validity and Applicability of the Revised Delirium Rating Scale (DRS-R98) for Delirium Severity Assessment in a Critical Care Setting. Journal of Intensive Care Medicine, 39 (3), 240-249. (doi:10.1177/08850666231199986).

Record type: Article

Abstract

Background: delirium is a neuropsychiatric syndrome common in critical illness. Worsening delirium severity is associated with poorer clinical outcomes, yet its assessment remains under-reported with most severity assessment tools not validated for critical care. The DRS-R98 is a widely applied and validated tool. The aim of this project is to report the validation and utility of the DRS-R98 in critical illness. 

Methods: this prospective, cohort study was conducted in adults with delirium admitted to a critical care unit and predicted to stay for ≥ 24 h. We excluded patients with severe neurological or communication barriers that would have interfered with the DRS-R98 assessment. Patients were screened using a delirium detection algorithm and the Confusion Assessment Method for the Intensive Care Unit. Eligible patient informations were collected and reported to qualified assessor/s before visiting clinical areas, confirming delirium presence and undertaking DRS- R98 assessments. To assess the tool's construct validity, an intensivist completed the Clinical Global Impression-Scale (CGI-S). To calculate the inter-rater reliability (IRR) a subset of patients were simultaneously evaluated by two assessors. 

Results: we assessed 22 patients, 73% were male, with a median age of 65 years (IQR14). The DRS -R98 mean (SD) severity score was 24 (+/-7.7), total scale was 29 (+/18.0), and CGI-S 3.5 (+/11.5). Assessment duration was 90 min (+/-55) and 15 min (+/-5) for record data extraction and clinical assessment respectively. The CGI-S significantly correlated with DRS-R98 severity (r = 0.626) and total (r = 0.628) scales. The DRS-R98 Cronbach's alpha was 0.896 for severity scale and 0.886 for total scale. The inter-rater reliability (IRR) was assessed in six patients and reported an inter-correlation coefficient of 0.505 (p = 0.124) and 0.565 (p = 0.93) for the severity and total scale respectively. 

Conclusions: in critical care, the Delirium Rating Scale R98 had good construct validity, excellent internal consistency, and moderate inter-rater reliability.

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almuhairi-et-al-2023-the-validity-and-applicability-of-the-revised-delirium-rating-scale-(drs-r98)-for-delirium - Version of Record
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e-pub ahead of print date: 5 September 2023
Keywords: critical care, delirium, intensive care, severity, validation

Identifiers

Local EPrints ID: 482304
URI: http://eprints.soton.ac.uk/id/eprint/482304
ISSN: 0885-0666
PURE UUID: 9546c61f-7a34-4dd0-8dbb-ab53158836bc
ORCID for Cathrine A. McKenzie: ORCID iD orcid.org/0000-0002-5190-9711

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Date deposited: 26 Sep 2023 16:41
Last modified: 30 Oct 2024 03:07

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Contributors

Author: Eiman Saeed Almuhairi
Author: Monica Badejo
Author: Aneesa Peer
Author: Mervi Pitkanen
Author: Cathrine A. McKenzie ORCID iD

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