Iterative synthetic strategies and gene deletant experiments enable the first identification of polysulfides in: Saccharomyces cerevisiae
Iterative synthetic strategies and gene deletant experiments enable the first identification of polysulfides in: Saccharomyces cerevisiae
New evidence on the role of H2S as a gasotransmitter suggests that the true signalling effectors are polysulfides. Both oxidized polysulfides and hydropolysulfides were synthesized and their presence in S. cerevisiae was observed for the first time. A single gene-deletant approach allowed observation of the modulation of polysulfide species and levels.
8868-8871
Pilkington, Lisa I.
1fe79f49-c605-406e-ad73-86ee0cf9a77d
Deed, Rebecca C.
6344c0da-181d-4c59-9ac4-4fb066d05493
Parish-Virtue, Katie
0ec5907e-8434-4419-bb5c-cbb07898fa80
Huang, Chien Wei
0d5b4c1c-21bc-4576-82c5-700903147c3f
Walker, Michelle E.
5e8a98ce-9e08-409a-99e4-a0b96a490940
Jiranek, Vladimir
8e5a8dfd-f5b2-43e3-928b-11dff324abc7
Barker, David
d42caf4b-8511-43ad-8316-e6e888f0bc22
Fedrizzi, Bruno
f6937102-e02d-4404-8820-bc564201822a
19 June 2019
Pilkington, Lisa I.
1fe79f49-c605-406e-ad73-86ee0cf9a77d
Deed, Rebecca C.
6344c0da-181d-4c59-9ac4-4fb066d05493
Parish-Virtue, Katie
0ec5907e-8434-4419-bb5c-cbb07898fa80
Huang, Chien Wei
0d5b4c1c-21bc-4576-82c5-700903147c3f
Walker, Michelle E.
5e8a98ce-9e08-409a-99e4-a0b96a490940
Jiranek, Vladimir
8e5a8dfd-f5b2-43e3-928b-11dff324abc7
Barker, David
d42caf4b-8511-43ad-8316-e6e888f0bc22
Fedrizzi, Bruno
f6937102-e02d-4404-8820-bc564201822a
Pilkington, Lisa I., Deed, Rebecca C., Parish-Virtue, Katie, Huang, Chien Wei, Walker, Michelle E., Jiranek, Vladimir, Barker, David and Fedrizzi, Bruno
(2019)
Iterative synthetic strategies and gene deletant experiments enable the first identification of polysulfides in: Saccharomyces cerevisiae.
Chemical Communications, 55 (60), .
(doi:10.1039/c9cc03020d).
Abstract
New evidence on the role of H2S as a gasotransmitter suggests that the true signalling effectors are polysulfides. Both oxidized polysulfides and hydropolysulfides were synthesized and their presence in S. cerevisiae was observed for the first time. A single gene-deletant approach allowed observation of the modulation of polysulfide species and levels.
This record has no associated files available for download.
More information
Accepted/In Press date: 18 June 2019
Published date: 19 June 2019
Additional Information:
Funding Information:
We thank the Faculty Research and Development Fund from The University of Auckland for supporting this research.
Publisher Copyright:
© 2019 The Royal Society of Chemistry.
Identifiers
Local EPrints ID: 482678
URI: http://eprints.soton.ac.uk/id/eprint/482678
ISSN: 1359-7345
PURE UUID: 7f56c27a-08b7-4bac-9932-43e4313f128e
Catalogue record
Date deposited: 11 Oct 2023 16:51
Last modified: 18 Mar 2024 04:12
Export record
Altmetrics
Contributors
Author:
Lisa I. Pilkington
Author:
Rebecca C. Deed
Author:
Katie Parish-Virtue
Author:
Chien Wei Huang
Author:
Michelle E. Walker
Author:
Vladimir Jiranek
Author:
David Barker
Author:
Bruno Fedrizzi
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics