Induction heating for the removal of liquid metal-based implant mimics: a proof-of-concept
Induction heating for the removal of liquid metal-based implant mimics: a proof-of-concept
Eutectic alloys have long been investigated for their unique properties such as single point melting temperature, homogenous structures, and uniform distribution of phases. In this work, we synthesized and characterized two low melting temperature liquid metal alloys. Eutectic alloys of indium-tin-bismuth (Field's metal) and Field's metal-like alloy with traces of zinc (0.4 wt%) were studied through a series of structural, thermal, microstructural, and mechanical tests. The in vitro biocompatibility of the alloys was assessed to investigate their potential application as bioimplants. These low melting point alloys (∼62 °C and ∼60 °C for Field's metal and the alloy with zinc, respectively) were utilized to address one of the major issues faced by the conventional use of bioimplants, which is the invasive surgery. We provide a proof-of-concept utilizing the combination of induction heating with the Field's metal-based alloys with suitable melting points. The approach enabled a contactless melting and extraction for the non-invasive removal of the bioimplant mimic from a polymer matrix, that can be potentially translated to the human body. We believe that this approach will provide fundamental insights for future biomedical applications and the design of liquid metal based non-invasive implants.
Biocompatibility, Implants, Low melting point, Post-transition metals, Zinc
Abbasi, Roozbeh
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Tang, Jianbo
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Baharfar, Mahroo
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Zhang, Chengchen
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Allioux, Francois Marie
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Zhang, Jin
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Tajik, Mohammad
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Yang, Jiong
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Biazik, Joanna
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Centurion, Franco
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Han, Jialuo
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Mofarah, Sajjad S.
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Esrafilzadeh, Dorna
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Koshy, Pramod
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Sorrell, Charles C.
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Chan, Sammy Lap Ip
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Rahim, Md Arifur
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Kalantar-Zadeh, Kourosh
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31 March 2022
Abbasi, Roozbeh
e052784f-2858-4c2d-aff8-2fee6fcd479d
Tang, Jianbo
87473905-8e35-48a1-a776-88080bb751b9
Baharfar, Mahroo
4f5e3122-2402-4c84-8513-cf24eeacf3ff
Zhang, Chengchen
abc47c06-4b99-4aed-be72-463f211e9dfa
Allioux, Francois Marie
06fa4c1f-9d93-4fa4-bff6-2b4b4d497e95
Zhang, Jin
929e49de-431b-4190-b107-f70e6beec50d
Tajik, Mohammad
29e71941-6210-47f8-ba5c-bee1e77a4947
Yang, Jiong
69a8f107-4f74-495f-9944-f15e966ef87c
Biazik, Joanna
22e0202e-d477-40ad-9f7a-edc84bd14978
Centurion, Franco
7b4b6572-ddbb-40d1-a79c-4681933fac76
Han, Jialuo
56fce4b1-540d-4619-8542-bc61548224ab
Mofarah, Sajjad S.
0b47f17e-61ca-49c1-982c-c0f11a7f30dd
Esrafilzadeh, Dorna
5b245c2f-64b0-4d63-8477-ef183d9ea152
Koshy, Pramod
5c95c336-7562-48aa-ab1f-9682f1213307
Sorrell, Charles C.
71a610d5-85e7-4079-847e-d98abdfa1965
Chan, Sammy Lap Ip
0edab805-8f68-43f6-ab36-e0406fad4af3
Rahim, Md Arifur
1a336538-113c-494c-9dd9-04e7f466f323
Kalantar-Zadeh, Kourosh
aded6a64-8612-40b7-aae9-233fbae916a6
Abbasi, Roozbeh, Tang, Jianbo, Baharfar, Mahroo, Zhang, Chengchen, Allioux, Francois Marie, Zhang, Jin, Tajik, Mohammad, Yang, Jiong, Biazik, Joanna, Centurion, Franco, Han, Jialuo, Mofarah, Sajjad S., Esrafilzadeh, Dorna, Koshy, Pramod, Sorrell, Charles C., Chan, Sammy Lap Ip, Rahim, Md Arifur and Kalantar-Zadeh, Kourosh
(2022)
Induction heating for the removal of liquid metal-based implant mimics: a proof-of-concept.
Applied Materials Today, 27, [101459].
(doi:10.1016/j.apmt.2022.101459).
Abstract
Eutectic alloys have long been investigated for their unique properties such as single point melting temperature, homogenous structures, and uniform distribution of phases. In this work, we synthesized and characterized two low melting temperature liquid metal alloys. Eutectic alloys of indium-tin-bismuth (Field's metal) and Field's metal-like alloy with traces of zinc (0.4 wt%) were studied through a series of structural, thermal, microstructural, and mechanical tests. The in vitro biocompatibility of the alloys was assessed to investigate their potential application as bioimplants. These low melting point alloys (∼62 °C and ∼60 °C for Field's metal and the alloy with zinc, respectively) were utilized to address one of the major issues faced by the conventional use of bioimplants, which is the invasive surgery. We provide a proof-of-concept utilizing the combination of induction heating with the Field's metal-based alloys with suitable melting points. The approach enabled a contactless melting and extraction for the non-invasive removal of the bioimplant mimic from a polymer matrix, that can be potentially translated to the human body. We believe that this approach will provide fundamental insights for future biomedical applications and the design of liquid metal based non-invasive implants.
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Accepted/In Press date: 19 March 2022
e-pub ahead of print date: 31 March 2022
Published date: 31 March 2022
Additional Information:
Funding Information:
The authors would like to acknowledge the Australian Research Council (ARC) Laureate Fellowship grant (FL180100053) for the financial coverage of this study. R. Abbasi thanks UNSW for the University International Postgraduate Award (UIPA) scholarship. Authors would like to acknowledge the technical assistance of the Mark Wainwright Analytical Center (Cell Culture Facility) at UNSW.
Publisher Copyright:
© 2022 Elsevier Ltd
Keywords:
Biocompatibility, Implants, Low melting point, Post-transition metals, Zinc
Identifiers
Local EPrints ID: 482907
URI: http://eprints.soton.ac.uk/id/eprint/482907
ISSN: 2352-9407
PURE UUID: aa05c406-161a-4b11-9597-1d9e9d5f0b92
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Date deposited: 17 Oct 2023 16:36
Last modified: 06 Jun 2024 02:19
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Contributors
Author:
Roozbeh Abbasi
Author:
Jianbo Tang
Author:
Mahroo Baharfar
Author:
Chengchen Zhang
Author:
Francois Marie Allioux
Author:
Jin Zhang
Author:
Mohammad Tajik
Author:
Jiong Yang
Author:
Joanna Biazik
Author:
Franco Centurion
Author:
Jialuo Han
Author:
Sajjad S. Mofarah
Author:
Dorna Esrafilzadeh
Author:
Pramod Koshy
Author:
Charles C. Sorrell
Author:
Sammy Lap Ip Chan
Author:
Md Arifur Rahim
Author:
Kourosh Kalantar-Zadeh
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