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The patient with thrombophilia

The patient with thrombophilia
The patient with thrombophilia

This chapter includes clinical cases, background, evidence-based practical management options, preventive measures, key-point summaries of thrombophilia and answers to questions patients ask. Thromboembolism is a rare complication of ovarian stimulation for IVF. Venous thrombosis is a potentially serious disorder which may often lead to post-thrombotic syndrome causing chronic morbidity. Because women undergoing IVF are generally young and active, this may afflict their lives for many years. screening for thrombophilia should be considered in women with a history of recurrent miscarriage, or personal or family history of venous thromboembolism (VTE). The management of the woman with a single previous VTE has been controversial, but data from studies of pregnancy may guide therapy in the context of IVF. Clinical reports of deep venous thrombosis occurring following IVF treatment indicate that it most frequently presents in early pregnancy between 5 and 10 weeks after human chorionic gonadotropin administration.

Deep venous thrombosis, IVF treatment, Ovarian stimulation, Thrombophilia, Venous thromboembolism
48-55
Wiley
Ranjan, Yorain Sri
6190507c-a19e-42ac-ada8-2b04299baa5e
Cheong, Ying C.
4efbba2a-3036-4dce-82f1-8b4017952c83
Sharif, Khaldoun
Coomarasamy, Arri
Ranjan, Yorain Sri
6190507c-a19e-42ac-ada8-2b04299baa5e
Cheong, Ying C.
4efbba2a-3036-4dce-82f1-8b4017952c83
Sharif, Khaldoun
Coomarasamy, Arri

Ranjan, Yorain Sri and Cheong, Ying C. (2021) The patient with thrombophilia. In, Sharif, Khaldoun and Coomarasamy, Arri (eds.) Assisted Reproduction Techniques: Challenges and Management Options. 2 ed. Wiley, pp. 48-55. (doi:10.1002/9781119622215.ch8).

Record type: Book Section

Abstract

This chapter includes clinical cases, background, evidence-based practical management options, preventive measures, key-point summaries of thrombophilia and answers to questions patients ask. Thromboembolism is a rare complication of ovarian stimulation for IVF. Venous thrombosis is a potentially serious disorder which may often lead to post-thrombotic syndrome causing chronic morbidity. Because women undergoing IVF are generally young and active, this may afflict their lives for many years. screening for thrombophilia should be considered in women with a history of recurrent miscarriage, or personal or family history of venous thromboembolism (VTE). The management of the woman with a single previous VTE has been controversial, but data from studies of pregnancy may guide therapy in the context of IVF. Clinical reports of deep venous thrombosis occurring following IVF treatment indicate that it most frequently presents in early pregnancy between 5 and 10 weeks after human chorionic gonadotropin administration.

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More information

e-pub ahead of print date: 4 June 2021
Keywords: Deep venous thrombosis, IVF treatment, Ovarian stimulation, Thrombophilia, Venous thromboembolism

Identifiers

Local EPrints ID: 483259
URI: http://eprints.soton.ac.uk/id/eprint/483259
PURE UUID: 587287b2-57e3-4836-a789-059c3c52f18e
ORCID for Ying C. Cheong: ORCID iD orcid.org/0000-0001-7687-4597

Catalogue record

Date deposited: 26 Oct 2023 17:07
Last modified: 18 Mar 2024 03:08

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Contributors

Author: Yorain Sri Ranjan
Author: Ying C. Cheong ORCID iD
Editor: Khaldoun Sharif
Editor: Arri Coomarasamy

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