High mitochondrial haplotype diversity found in three Pre-Hispanic roups from Colombia
High mitochondrial haplotype diversity found in three Pre-Hispanic roups from Colombia
The analysis of mitochondrial DNA (mtDNA) hypervariable region (HVR) sequence data from ancient human remains provides valuable insights into the genetic structure and population dynamics of ancient populations. mtDNA is particularly useful in studying ancient populations, because it is maternally inherited and has a higher mutation rate compared to nuclear DNA. To determine the genetic structure of three Colombian pre-Hispanic populations and compare them with current populations, we determined the haplotypes from human bone remains by sequencing several mitochondrial DNA segments. A wide variety of mitochondrial polymorphisms were obtained from 33 samples. Our results support a high population heterogeneity among pre-Hispanic populations in Colombia.
Colombia, ancient DNA, mtDNA HVS-I, native American ancestries, native American founding lineages, native American genetic history, pre-Hispanic
Uricoechea Patiño, Daniel
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Collins, Andrew
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García, Oscar Julián Romero
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Santos Vecino, Gustavo
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Cuenca, José Vicente Rodríguez
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Bernal, Jaime E.
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Benavides Benítez, Escilda
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Vergara Muñoz, Saray
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Briceño Balcázar, Ignacio
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October 2023
Uricoechea Patiño, Daniel
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Collins, Andrew
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García, Oscar Julián Romero
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Santos Vecino, Gustavo
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Cuenca, José Vicente Rodríguez
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Bernal, Jaime E.
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Benavides Benítez, Escilda
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Vergara Muñoz, Saray
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Briceño Balcázar, Ignacio
4bf78e12-bd86-4318-9ad4-258faf2530f2
Uricoechea Patiño, Daniel, Collins, Andrew, García, Oscar Julián Romero, Santos Vecino, Gustavo, Cuenca, José Vicente Rodríguez, Bernal, Jaime E., Benavides Benítez, Escilda, Vergara Muñoz, Saray and Briceño Balcázar, Ignacio
(2023)
High mitochondrial haplotype diversity found in three Pre-Hispanic roups from Colombia.
Genes, 14 (10), [1853].
(doi:10.3390/genes14101853).
Abstract
The analysis of mitochondrial DNA (mtDNA) hypervariable region (HVR) sequence data from ancient human remains provides valuable insights into the genetic structure and population dynamics of ancient populations. mtDNA is particularly useful in studying ancient populations, because it is maternally inherited and has a higher mutation rate compared to nuclear DNA. To determine the genetic structure of three Colombian pre-Hispanic populations and compare them with current populations, we determined the haplotypes from human bone remains by sequencing several mitochondrial DNA segments. A wide variety of mitochondrial polymorphisms were obtained from 33 samples. Our results support a high population heterogeneity among pre-Hispanic populations in Colombia.
Text
genes-14-01853
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More information
Accepted/In Press date: 18 September 2023
e-pub ahead of print date: 23 September 2023
Published date: October 2023
Additional Information:
Funding Information:
This research was funded by Universidad de La Sabana through the Convocatoria interna de 2013 (Internal Call of 2013) according to acta 809 de la comisión de asuntos generales, proyecto MED-168-2013. The APC (article processing charge) was funded by Universidad de La Sabana.
Publisher Copyright:
© 2023 by the authors.
Keywords:
Colombia, ancient DNA, mtDNA HVS-I, native American ancestries, native American founding lineages, native American genetic history, pre-Hispanic
Identifiers
Local EPrints ID: 483458
URI: http://eprints.soton.ac.uk/id/eprint/483458
ISSN: 2073-4425
PURE UUID: f1bda696-4f1c-49ef-8612-25d5a91e319d
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Date deposited: 31 Oct 2023 17:41
Last modified: 18 Mar 2024 02:38
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Contributors
Author:
Daniel Uricoechea Patiño
Author:
Oscar Julián Romero García
Author:
Gustavo Santos Vecino
Author:
José Vicente Rodríguez Cuenca
Author:
Jaime E. Bernal
Author:
Escilda Benavides Benítez
Author:
Saray Vergara Muñoz
Author:
Ignacio Briceño Balcázar
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