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Defining a childhood type 1 diabetes cohort, clinical practice measures, and outcomes within administrative data in British Columbia

Defining a childhood type 1 diabetes cohort, clinical practice measures, and outcomes within administrative data in British Columbia
Defining a childhood type 1 diabetes cohort, clinical practice measures, and outcomes within administrative data in British Columbia

Objective: we used administrative data to: 1) establish a cohort of individuals with childhood-onset type 1 diabetes (T1D) in British Columbia (BC); and 2) define T1D-related clinical practice measures. 

Methods: we applied a validated diabetes case finding definition and differentiating algorithm to linked administrative data (1992–1993 to 2019–2020). Cases were removed when they did not meet inclusion criteria for childhood-onset T1D. Clinical practice measures were defined based on clinical practice guidelines. 

Results: we developed an administrative cohort that included 5,901 individuals with childhood diagnosed T1D between April 1, 1996 and March 31, 2020. The mean age was 22.31 (standard deviation 8.21) years. Clinical practice measures derived included diabetes outpatient visits (N=4,935) and glycated hemoglobin tests (N=4,935), and screening for thyroid function (N=4,457), retinopathy (N=1,602), and nephropathy (N=2,369). 

Conclusions: we established an administrative cohort of ∼6,000 individuals with childhood-onset T1D with 20 + years of follow-up data that can be used to describe the association between clinical practice measures and clinical outcomes.

administrative health data, childhood diabetes, outcome measures
1499-2671
Fox, Danya
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Zhang, Qian
b13b310a-0eb7-4ad5-ac74-6c8b69116cfd
Islam, Nazrul
e5345196-7479-438f-b4f6-c372d2135586
Chen, Leo
c54eb6e3-a5df-4867-953e-9bac21b8a747
Leung, Joseph
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Bone, Jeffrey
2d627e72-d2a9-4800-a143-2e949ffec18d
Amed, Shazhan
c3afda99-2743-404a-ba72-38eb0fcc69dc
Fox, Danya
8aa6a667-88de-4ca4-81f2-2ce339199980
Zhang, Qian
b13b310a-0eb7-4ad5-ac74-6c8b69116cfd
Islam, Nazrul
e5345196-7479-438f-b4f6-c372d2135586
Chen, Leo
c54eb6e3-a5df-4867-953e-9bac21b8a747
Leung, Joseph
9e9b6c8c-ab7a-45e5-a6a6-0acf5af0a35e
Bone, Jeffrey
2d627e72-d2a9-4800-a143-2e949ffec18d
Amed, Shazhan
c3afda99-2743-404a-ba72-38eb0fcc69dc

Fox, Danya, Zhang, Qian, Islam, Nazrul, Chen, Leo, Leung, Joseph, Bone, Jeffrey and Amed, Shazhan (2023) Defining a childhood type 1 diabetes cohort, clinical practice measures, and outcomes within administrative data in British Columbia. Canadian Journal of Diabetes. (doi:10.1016/j.jcjd.2023.08.007).

Record type: Article

Abstract

Objective: we used administrative data to: 1) establish a cohort of individuals with childhood-onset type 1 diabetes (T1D) in British Columbia (BC); and 2) define T1D-related clinical practice measures. 

Methods: we applied a validated diabetes case finding definition and differentiating algorithm to linked administrative data (1992–1993 to 2019–2020). Cases were removed when they did not meet inclusion criteria for childhood-onset T1D. Clinical practice measures were defined based on clinical practice guidelines. 

Results: we developed an administrative cohort that included 5,901 individuals with childhood diagnosed T1D between April 1, 1996 and March 31, 2020. The mean age was 22.31 (standard deviation 8.21) years. Clinical practice measures derived included diabetes outpatient visits (N=4,935) and glycated hemoglobin tests (N=4,935), and screening for thyroid function (N=4,457), retinopathy (N=1,602), and nephropathy (N=2,369). 

Conclusions: we established an administrative cohort of ∼6,000 individuals with childhood-onset T1D with 20 + years of follow-up data that can be used to describe the association between clinical practice measures and clinical outcomes.

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Accepted/In Press date: 22 August 2023
e-pub ahead of print date: 29 August 2023
Additional Information: Funding Information: This study was funded by the BC Children’s Hospital Foundation . Access to data is subject to approval but can be requested for research projects through the data steward(s) or their designated service providers. All inferences, opinions, and conclusions drawn in this article are those of the authors, and do not reflect the opinions or policies of the data steward(s).
Keywords: administrative health data, childhood diabetes, outcome measures

Identifiers

Local EPrints ID: 483638
URI: http://eprints.soton.ac.uk/id/eprint/483638
ISSN: 1499-2671
PURE UUID: 99fadcda-8e10-4cfa-9599-ab2b55884a3e
ORCID for Nazrul Islam: ORCID iD orcid.org/0000-0003-3982-4325

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Date deposited: 02 Nov 2023 18:01
Last modified: 29 Aug 2024 04:01

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Contributors

Author: Danya Fox
Author: Qian Zhang
Author: Nazrul Islam ORCID iD
Author: Leo Chen
Author: Joseph Leung
Author: Jeffrey Bone
Author: Shazhan Amed

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