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The geometry of cell fate

The geometry of cell fate
The geometry of cell fate
Waddington's epigenetic landscape is a powerful metaphor for development. Recent work shows how molecular "noise" can shape the architecture of this landscape and how universal properties of cell fate commitment can be distilled from careful consideration of its geometry.
Cell Differentiation, Epigenesis, Genetic/genetics, Epigenomics
1-3
MacArthur, Ben D.
2c0476e7-5d3e-4064-81bb-104e8e88bb6b
MacArthur, Ben D.
2c0476e7-5d3e-4064-81bb-104e8e88bb6b

MacArthur, Ben D. (2022) The geometry of cell fate. Cell Systems, 13 (1), 1-3. (doi:10.1016/j.cels.2021.12.001).

Record type: Letter

Abstract

Waddington's epigenetic landscape is a powerful metaphor for development. Recent work shows how molecular "noise" can shape the architecture of this landscape and how universal properties of cell fate commitment can be distilled from careful consideration of its geometry.

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More information

e-pub ahead of print date: 19 January 2022
Published date: 19 January 2022
Keywords: Cell Differentiation, Epigenesis, Genetic/genetics, Epigenomics

Identifiers

Local EPrints ID: 484362
URI: http://eprints.soton.ac.uk/id/eprint/484362
PURE UUID: 715d96ab-5f49-4bb5-95d4-4d55deca1a56
ORCID for Ben D. MacArthur: ORCID iD orcid.org/0000-0002-5396-9750

Catalogue record

Date deposited: 15 Nov 2023 18:27
Last modified: 17 Mar 2024 02:51

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