Optimising nutrition during therapeutic hypothermia
Optimising nutrition during therapeutic hypothermia
There is little evidence to inform provision of enteral or parenteral nutrition to infants with hypoxic ischaemic encephalopathy (HIE) during and soon after therapeutic hypothermia; as a consequence, clinical practice is both variable and changing. A 2014 UK survey found that 79% (33 of 42) of responding neonatal units routinely withheld enteral nutrition during cooling; 3 years later, a similar survey found that 41% (20 of 49) of responding units reported withholding enteral nutrition.1 The latter study also reports wide variation in how, when and how much to feed, and in the use of parenteral nutrition. Internationally, practice is even more variable: withholding enteral feeds is practised almost universally2 in some countries, while in others, milk feeding during hypothermia is routine.3 Here we discuss the limited evidence available to inform enteral and parenteral nutrition during therapeutic hypothermia.
hypothermia induced, hypoxia-ischaemia brain, infant feeding, infant newborn, intensive care neonatal, NNRD, parenteral nutrition
F230-F231
Ojha, Shalini
adc62cc2-df92-446f-8ad2-4c0cf006d689
Dorling, Jon
e55dcb9a-a798-41a1-8753-9e9ff8aab630
Battersby, Cheryl
24ba455f-7f54-427c-8732-3007926ee5ce
Longford, Nicholas
2f3303da-6aa2-49e7-bb14-df151389aee2
Gale, Chris
210b7c81-9a39-460a-9ab3-54fe92a69f8e
Ojha, Shalini
adc62cc2-df92-446f-8ad2-4c0cf006d689
Dorling, Jon
e55dcb9a-a798-41a1-8753-9e9ff8aab630
Battersby, Cheryl
24ba455f-7f54-427c-8732-3007926ee5ce
Longford, Nicholas
2f3303da-6aa2-49e7-bb14-df151389aee2
Gale, Chris
210b7c81-9a39-460a-9ab3-54fe92a69f8e
Ojha, Shalini, Dorling, Jon, Battersby, Cheryl, Longford, Nicholas and Gale, Chris
(2018)
Optimising nutrition during therapeutic hypothermia.
Archives of Disease in Childhood: Fetal and Neonatal Edition, 104 (3), .
(doi:10.1136/archdischild-2018-315393).
Abstract
There is little evidence to inform provision of enteral or parenteral nutrition to infants with hypoxic ischaemic encephalopathy (HIE) during and soon after therapeutic hypothermia; as a consequence, clinical practice is both variable and changing. A 2014 UK survey found that 79% (33 of 42) of responding neonatal units routinely withheld enteral nutrition during cooling; 3 years later, a similar survey found that 41% (20 of 49) of responding units reported withholding enteral nutrition.1 The latter study also reports wide variation in how, when and how much to feed, and in the use of parenteral nutrition. Internationally, practice is even more variable: withholding enteral feeds is practised almost universally2 in some countries, while in others, milk feeding during hypothermia is routine.3 Here we discuss the limited evidence available to inform enteral and parenteral nutrition during therapeutic hypothermia.
Text
F230.full
- Version of Record
More information
Accepted/In Press date: 20 September 2018
e-pub ahead of print date: 15 October 2018
Additional Information:
Funding Information:
received grants and fellowships from National Institute of Heath Research (NIHR) and the Academy of Medical Sciences; he has been awarded British Association of Perinatal Medicine (BAPM) Travel Awards, which are supported by Chiesi Pharmaceuticals, to attend educational conferences outside the submitted work. CG, CB and NL work in the Neonatal Data Analysis Unit (NDAU) which houses the National Neonatal Research Database (NNRD). CG and CB do not receive salary or other financial reimbursement from the NDAU. NL is employed by the NDAU as a senior statistician. In the last 12 years, JD has received grants from National Institute of Heath Research (NIHR), Bliss and Action Medical Research.
Funding CG is funded by the UK Medical Research Council (MRC) through a Clinician Scientist Fellowship award. All authors are coinvestigators on the NIHR HTA funded project 16/79/03: Optimising newborn nutrition during therapeutic hypothermia: an observational study using routinely collected data.
Keywords:
hypothermia induced, hypoxia-ischaemia brain, infant feeding, infant newborn, intensive care neonatal, NNRD, parenteral nutrition
Identifiers
Local EPrints ID: 484985
URI: http://eprints.soton.ac.uk/id/eprint/484985
ISSN: 1359-2998
PURE UUID: 410c5999-bd30-4cc3-990b-0ffb8d3fc834
Catalogue record
Date deposited: 27 Nov 2023 17:52
Last modified: 18 Mar 2024 04:16
Export record
Altmetrics
Contributors
Author:
Shalini Ojha
Author:
Jon Dorling
Author:
Cheryl Battersby
Author:
Nicholas Longford
Author:
Chris Gale
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics