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Feeding growth restricted preterm infants with abnormal antenatal Doppler results

Feeding growth restricted preterm infants with abnormal antenatal Doppler results
Feeding growth restricted preterm infants with abnormal antenatal Doppler results

Absence or reversal of end diastolic flow (AREDF) in the umbilical artery is associated with poor outcome, and elective premature delivery is common. Feeding these infants is a challenge. They often have poor tolerance of enteral feeding, and necrotising enterocolitis may develop. This review explores current practice to see if there is evidence on which to base guidelines. The incidence of necrotising enterocolitis is increased in infants with fetal AREDF, especially when complicated by fetal growth restriction. Abnormalities of splanchnic blood Flow persist postnatally, with some recovery during the first week of life, providing justification for a delayed and careful introduction of enteral feeding. Such a policy exposes babies to the risks of parenteral nutrition, with no trials to date showing any benefit of delayed enteral nutrition. Trials are required to determine the optimum timing for introduction of enteral feeds in growth restricted infants with fetal AREDF.

1359-2998
F359-F363
Dorling, J.
e55dcb9a-a798-41a1-8753-9e9ff8aab630
Kempley, S.
b721734b-5d0c-4833-a1cc-eab0d7758c18
Leaf, A.
380f75d8-ccbd-4538-a45a-c4912fd86fc3
Dorling, J.
e55dcb9a-a798-41a1-8753-9e9ff8aab630
Kempley, S.
b721734b-5d0c-4833-a1cc-eab0d7758c18
Leaf, A.
380f75d8-ccbd-4538-a45a-c4912fd86fc3

Dorling, J., Kempley, S. and Leaf, A. (2005) Feeding growth restricted preterm infants with abnormal antenatal Doppler results. Archives of Disease in Childhood: Fetal and Neonatal Edition, 90 (5), F359-F363. (doi:10.1136/adc.2004.060350).

Record type: Review

Abstract

Absence or reversal of end diastolic flow (AREDF) in the umbilical artery is associated with poor outcome, and elective premature delivery is common. Feeding these infants is a challenge. They often have poor tolerance of enteral feeding, and necrotising enterocolitis may develop. This review explores current practice to see if there is evidence on which to base guidelines. The incidence of necrotising enterocolitis is increased in infants with fetal AREDF, especially when complicated by fetal growth restriction. Abnormalities of splanchnic blood Flow persist postnatally, with some recovery during the first week of life, providing justification for a delayed and careful introduction of enteral feeding. Such a policy exposes babies to the risks of parenteral nutrition, with no trials to date showing any benefit of delayed enteral nutrition. Trials are required to determine the optimum timing for introduction of enteral feeds in growth restricted infants with fetal AREDF.

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Published date: September 2005

Identifiers

Local EPrints ID: 485047
URI: http://eprints.soton.ac.uk/id/eprint/485047
ISSN: 1359-2998
PURE UUID: 009e5fe4-67a4-46c1-8fe7-90feb8dc950b
ORCID for J. Dorling: ORCID iD orcid.org/0000-0002-1691-3221

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Date deposited: 28 Nov 2023 18:02
Last modified: 18 Mar 2024 04:16

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Contributors

Author: J. Dorling ORCID iD
Author: S. Kempley
Author: A. Leaf

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