Prevalence of human papillomavirus infection, cervical intraepithelial neoplasia and cervical cancer in imprisoned women worldwide: a systematic review and meta-analysis
Prevalence of human papillomavirus infection, cervical intraepithelial neoplasia and cervical cancer in imprisoned women worldwide: a systematic review and meta-analysis
Background and objectives: imprisoned women have higher rates of abnormalities at cervical screening and some studies suggest that cervical cancer is the most common cancer in this population. The aim of this work was to summarise the current evidence on the prevalence of human papilloma virus (HPV) infection, cervical cancer and precancerous lesions in women in prison worldwide and to compare these rates with the general population.
Methods: we systematically searched and reviewed published and unpublished data reporting the prevalence of any HPV infection, cervical intraepithelial neoplasia (CIN) and cervical cancer in imprisoned women. We created forest plots with prevalence estimates from studies with comparable outcomes and of prevalence ratios using data from national screening programmes as a comparison group.
Findings: a total of 53 533 imprisoned women from 10 countries and 35 studies were included in the review. The prevalence of HPV among prisoners ranged from 10.5% to 55.4% with significant heterogeneity. The prevalence of CIN diagnosed by cytology in prisoners ranged from 0% to 22%. Ratios comparing the prevalence of CIN in imprisoned women to that in the community ranged from 1.13 to 5.46. Cancer prevalence estimates were at least 100 times higher than in populations participating in national screening programmes.
Conclusion: imprisoned women are at higher risk of cervical cancer than the general population. There is a high prevalence of HPV infection and precancerous lesions in this population. Targeted programmes for control of risk factors and the development of more effective cervical screening programmes are recommended.
Prospero registration number: CRD42014009690.
Adult, Female, Humans, Middle Aged, Papillomaviridae/isolation & purification, Papillomavirus Infections/diagnosis, Prevalence, Prisoners/statistics & numerical data, Prisons, Uterine Cervical Neoplasms/diagnosis, Uterine Cervical Dysplasia/diagnosis
95-102
Escobar, Nadia
39f708d2-1132-4297-b90e-36f096c789ec
Plugge, Emma
b64d2086-6cf2-4fae-98bf-6aafa3115b35
10 December 2019
Escobar, Nadia
39f708d2-1132-4297-b90e-36f096c789ec
Plugge, Emma
b64d2086-6cf2-4fae-98bf-6aafa3115b35
Escobar, Nadia and Plugge, Emma
(2019)
Prevalence of human papillomavirus infection, cervical intraepithelial neoplasia and cervical cancer in imprisoned women worldwide: a systematic review and meta-analysis.
Journal of Epidemiology and Community Health, 74, .
(doi:10.1136/jech-2019-212557).
Abstract
Background and objectives: imprisoned women have higher rates of abnormalities at cervical screening and some studies suggest that cervical cancer is the most common cancer in this population. The aim of this work was to summarise the current evidence on the prevalence of human papilloma virus (HPV) infection, cervical cancer and precancerous lesions in women in prison worldwide and to compare these rates with the general population.
Methods: we systematically searched and reviewed published and unpublished data reporting the prevalence of any HPV infection, cervical intraepithelial neoplasia (CIN) and cervical cancer in imprisoned women. We created forest plots with prevalence estimates from studies with comparable outcomes and of prevalence ratios using data from national screening programmes as a comparison group.
Findings: a total of 53 533 imprisoned women from 10 countries and 35 studies were included in the review. The prevalence of HPV among prisoners ranged from 10.5% to 55.4% with significant heterogeneity. The prevalence of CIN diagnosed by cytology in prisoners ranged from 0% to 22%. Ratios comparing the prevalence of CIN in imprisoned women to that in the community ranged from 1.13 to 5.46. Cancer prevalence estimates were at least 100 times higher than in populations participating in national screening programmes.
Conclusion: imprisoned women are at higher risk of cervical cancer than the general population. There is a high prevalence of HPV infection and precancerous lesions in this population. Targeted programmes for control of risk factors and the development of more effective cervical screening programmes are recommended.
Prospero registration number: CRD42014009690.
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More information
Accepted/In Press date: 30 September 2019
e-pub ahead of print date: 23 October 2019
Published date: 10 December 2019
Keywords:
Adult, Female, Humans, Middle Aged, Papillomaviridae/isolation & purification, Papillomavirus Infections/diagnosis, Prevalence, Prisoners/statistics & numerical data, Prisons, Uterine Cervical Neoplasms/diagnosis, Uterine Cervical Dysplasia/diagnosis
Identifiers
Local EPrints ID: 485230
URI: http://eprints.soton.ac.uk/id/eprint/485230
ISSN: 0143-005X
PURE UUID: f6df225b-3939-4689-a88a-2b2226699c99
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Date deposited: 01 Dec 2023 17:44
Last modified: 18 Mar 2024 03:57
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Author:
Nadia Escobar
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